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Protein-protein interactions (PPIs) govern nearly all cellular processes, yet computational methods for identifying binding partners typically produce ranked predictions without mechanistic justification. This creates a fundamental barrier…

Quantitative Methods · Quantitative Biology 2026-05-22 Kingsley Yeon , Xuefeng Liu , Promit Ghosal

Rule learning-based models are widely used in highly interpretable scenarios due to their transparent structures. Inductive logic programming (ILP), a form of machine learning, induces rules from facts while maintaining interpretability.…

Artificial Intelligence · Computer Science 2026-02-17 Kun Gao , Katsumi Inoue , Yongzhi Cao , Hanpin Wang , Feng Yang

We focus on the problem of inducing logic programs that explain models learned by the support vector machine (SVM) algorithm. The top-down sequential covering inductive logic programming (ILP) algorithms (e.g., FOIL) apply hill-climbing…

Artificial Intelligence · Computer Science 2020-08-11 Farhad Shakerin , Gopal Gupta

Rules complement and extend ontologies on the Semantic Web. We refer to these rules as onto-relational since they combine DL-based ontology languages and Knowledge Representation formalisms supporting the relational data model within the…

Artificial Intelligence · Computer Science 2012-10-30 Francesca A. Lisi

Enzyme is the major workhorse to carry out the diverse cellular functions. It catalyzes the biological reactions with a high specificity, with its topology playing a crucial role. For ecologically safe production of numerous bioproducts…

Biomolecules · Quantitative Biology 2021-06-04 Prabha Sankara Narayanan , Ashish Runthala

We present an approach to automatically synthesise recursive predicates in Separation Logic (SL) from concrete data structure instances using Inductive Logic Programming (ILP) techniques. The main challenges to make such synthesis effective…

Programming Languages · Computer Science 2025-02-21 Ziyi Yang , Ilya Sergey

A particularly successful role for Inductive Logic Programming (ILP) is as a tool for discovering useful relational features for subsequent use in a predictive model. Conceptually, the case for using ILP to construct relational features…

Machine Learning · Computer Science 2014-09-12 Haimonti Dutta , Ashwin Srinivasan

Significant research has been conducted in recent years to extend Inductive Logic Programming (ILP) methods to induce Answer Set Programs (ASP). These methods perform an exhaustive search for the correct hypothesis by encoding an ILP…

Logic in Computer Science · Computer Science 2018-02-20 Farhad Shakerin , Gopal Gupta

My research explores integrating deep learning and logic programming to set the basis for a new generation of AI systems. By combining neural networks with Inductive Logic Programming (ILP), the goal is to construct systems that make…

Logic in Computer Science · Computer Science 2025-02-14 Talissa Dreossi

A major challenge in inductive logic programming (ILP) is learning large programs. We argue that a key limitation of existing systems is that they use entailment to guide the hypothesis search. This approach is limited because entailment is…

Artificial Intelligence · Computer Science 2020-04-23 Andrew Cropper , Sebastijan Dumančić

Answering science questions posed in natural language is an important AI challenge. Answering such questions often requires non-trivial inference and knowledge that goes beyond factoid retrieval. Yet, most systems for this task are based on…

Artificial Intelligence · Computer Science 2016-04-21 Daniel Khashabi , Tushar Khot , Ashish Sabharwal , Peter Clark , Oren Etzioni , Dan Roth

The goal of Inductive Logic Programming (ILP) is to learn a program that explains a set of examples. Until recently, most research on ILP targeted learning Prolog programs. The ILASP system instead learns Answer Set Programs (ASP). Learning…

Artificial Intelligence · Computer Science 2022-01-19 Mark Law

Common criticisms of state-of-the-art machine learning include poor generalisation, a lack of interpretability, and a need for large amounts of training data. We survey recent work in inductive logic programming (ILP), a form of machine…

Artificial Intelligence · Computer Science 2020-04-23 Andrew Cropper , Sebastijan Dumančić , Stephen H. Muggleton

Formally verifying the correctness of mathematical proofs is more accessible than ever, however, the learning curve remains steep for many of the state-of-the-art interactive theorem provers (ITP). Deriving the most appropriate subsequent…

Logic in Computer Science · Computer Science 2024-11-05 Liao Zhang , David M. Cerna , Cezary Kaliszyk

The goal of inductive logic programming is to induce a logic program (a set of logical rules) that generalises training examples. Inducing programs with many rules and literals is a major challenge. To tackle this challenge, we introduce an…

Machine Learning · Computer Science 2023-08-21 Andrew Cropper , Céline Hocquette

We propose ILP-CoT, a method that bridges Inductive Logic Programming (ILP) and Multimodal Large Language Models (MLLMs) for abductive logical rule induction. The task involves both discovering logical facts and inducing logical rules from…

Machine Learning · Computer Science 2025-09-29 Yifei Peng , Yaoli Liu , Enbo Xia , Yu Jin , Wang-Zhou Dai , Zhong Ren , Yao-Xiang Ding , Kun Zhou

Domain-specific heuristics are a crucial technique for the efficient solving of problems that are large or computationally hard. Answer Set Programming (ASP) systems support declarative specifications of domain-specific heuristics to…

Artificial Intelligence · Computer Science 2023-08-31 Richard Comploi-Taupe

Inductive logic programming (ILP) has been a deeply influential paradigm in AI, enjoying decades of research on its theory and implementations. As a natural descendent of the fields of logic programming and machine learning, it admits the…

Artificial Intelligence · Computer Science 2020-01-16 Vaishak Belle

Many inductive logic programming (ILP) methods are incapable of learning programs from probabilistic background knowledge, e.g. coming from sensory data or neural networks with probabilities. We propose Propper, which handles flawed and…

Artificial Intelligence · Computer Science 2024-09-23 Fieke Hillerstrom , Gertjan Burghouts

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai