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Competitive dynamics are thought to occur in many processes of learning involving synaptic plasticity. Here we show, in a game theory-inspired model of synaptic interactions, that the competition between synapses in their weak and strong…

Disordered Systems and Neural Networks · Physics 2015-05-28 Gaurang Mahajan , Anita Mehta

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

Most decisions require information gathering from a stimulus presented with different gaps. Indeed, the brain process of this integration is rarely ambiguous. Recently, it has been claimed that humans can optimally integrate the information…

Neurons and Cognition · Quantitative Biology 2018-10-29 Maryam Tohidi-Moghaddam , Sajjad Zabbah , Farzaneh Olianezhad , Reza Ebrahimpour

In the paper, elements of the system theory of time are presented, mathematical models for time are constructed, and various properties are deduced from the main principles of the system theory of time. This theory is a far-reaching…

General Physics · Physics 2007-05-23 Mark Burgin

Time is deeply woven into how people perceive, and communicate about the world. Almost unconsciously, we provide our language utterances with temporal cues, like verb tenses, and we can hardly produce sentences without such cues. Extracting…

Computation and Language · Computer Science 2020-05-18 Artuur Leeuwenberg , Marie-Francine Moens

Biological systems often choose actions without an explicit reward signal, a phenomenon known as intrinsic motivation. The computational principles underlying this behavior remain poorly understood. In this study, we investigate an…

Artificial Intelligence · Computer Science 2023-01-05 Stas Tiomkin , Ilya Nemenman , Daniel Polani , Naftali Tishby

Circadian rhythms are acquired through evolution to increase the chances for survival through synchronizing with the daylight cycle. Reliable synchronization is realized through two trade-off properties: regularity to keep time precisely,…

Biological Physics · Physics 2014-10-02 Yoshihiko Hasegawa , Masanori Arita

Brains adapt to the statistical structure of their input. In the visual system, local light intensities change rapidly, the variance of the intensity changes more slowly, and the dynamic range of contrast itself changes more slowly still.…

Neurons and Cognition · Quantitative Biology 2025-09-03 Charles J. Edelson , Sima Setayeshgar , William Bialek , Rob R. de Ruyter van Steveninck

Living organisms process information to interact and adapt to their changing environment with the goal of finding food, mates or averting hazards. The structure of their niche has profound repercussions by both selecting their internal…

Physics and Society · Physics 2017-06-07 Hannes Hornischer , Stephan Herminghaus , Marco G. Mazza

We humans seem to have an innate understanding of the asymmetric progression of time, which we use to efficiently and safely perceive and manipulate our environment. Drawing inspiration from that, we address the problem of learning an arrow…

Machine Learning · Computer Science 2019-07-03 Nasim Rahaman , Steffen Wolf , Anirudh Goyal , Roman Remme , Yoshua Bengio

Many biological systems can sense periodical variations in a stimulus input and produce well-timed, anticipatory responses after the input is removed. Such systems show memory effects for retaining timing information in the stimulus and…

Neurons and Cognition · Quantitative Biology 2015-09-09 Ying-Jen Yang , Chun-Chung Chen , Pik-Yin Lai , C. K. Chan

Understanding how biological organisms make decisions is of fundamental importance in understanding behavior. Such an understanding within evolutionary game theory so far has been sought by appealing to bounded rationality. Here, we present…

Populations and Evolution · Quantitative Biology 2025-12-16 Mohammad Salahshour

Much work has been done to investigate social jetlag, a misalignment between the biological clock and the social agenda caused by exposition to different light inputs, that causes several health issues. To investigate synchronization and…

Adaptation and Self-Organizing Systems · Physics 2021-02-24 Flávia M. Ruziska , Iberê L. Caldas

The relationship between physiological systems and modern electromechanical technologies is fast becoming intimate with high degrees of complex interaction. It can be argued that muscular function, limb movements, and touch perception serve…

Human-Computer Interaction · Computer Science 2012-03-15 Bradly Alicea

Neural activity exhibits a vast range of timescales that can be several fold larger than the membrane time constant of individual neurons. Two types of mechanisms have been proposed to explain this conundrum. One possibility is that large…

Neurons and Cognition · Quantitative Biology 2019-03-26 Manuel Beiran , Srdjan Ostojic

Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…

Neurons and Cognition · Quantitative Biology 2024-09-23 Pantelis Vafidis , Antonio Rangel

The deep connection between entropy and information is discussed in terms of both classical and quantum physics. The mechanism of information transfer between systems via entanglement is explored in the context of decoherence theory. The…

Quantum Physics · Physics 2021-01-05 Martin Paul Vaughan

Many real-life decisions involve both perceptual processes and weighing the consequences of different actions. However, the neural mechanisms underlying perceptual decisions have typically been examined separately from those underlying…

Neurons and Cognition · Quantitative Biology 2025-02-07 Xiaoyue Zhu , Jeffrey C. Erlich

Multiple interlinked positive feedback loops shape the stimulus responses of various biochemical systems, such as the cell cycle or intracellular calcium release. Recent studies with simplified models have identified two advantages of…

Molecular Networks · Quantitative Biology 2012-08-31 Paul Smolen , Douglas A. Baxter , John H. Byrne

This paper shows how a time series of measurements of an evolving system can be processed to create an inner time series that is unaffected by any instantaneous invertible, possibly nonlinear transformation of the measurements. An inner…

Methodology · Statistics 2017-03-28 David N. Levin