Related papers: Kalman inversion stress microscopy
We show that the atomic force microscope can perform stress relaxation and creep compliance measurements on living cells. We propose a method to obtain the mechanical properties of the studied biomaterial: the relaxation time, the elastic…
Measuring stress fields in fluids and soft materials is crucial in various fields such as mechanical engineering, medicine, and bioengineering. However, conventional methods that calculate stress fields from velocity fields struggle to…
The connection between the properties of cell tissue and those of the single constituent cells remains to be elucidated. At the purely mechanical level, the degree of rigidity of different cellular components, such as the nucleus and the…
Mechanobiology is gaining more and more traction as the fundamental role of physical forces in biological function becomes clearer. Forces at the microscale are often measured indirectly using inverse problems such as Traction Force…
The vertex model is a popular framework for modelling tightly packed biological cells, such as confluent epithelia. Cells are described by convex polygons tiling the plane and their equilibrium is found by minimizing a global mechanical…
Knowledge of the global magnetic field distribution and its evolution on the Sun's surface is crucial for modeling the coronal magnetic field, understanding solar wind dynamics, computing the heliospheric open flux distribution and…
Coordinated cellular movements are key processes in tissue morphogenesis. Using a cell-based modeling approach we study the dynamics of epithelial layers lining surfaces with constant and varying curvature. We demonstrate that extrinsic…
By modifying and calibrating an active vertex model to experiments, we have simulated numerically a confluent cellular monolayer spreading on an empty space and the collision of two monolayers of different cells in an antagonistic migration…
The grip force required to handle an object depends on the object's mass and the friction coefficient of its surface. The control of grip force in myoelectric prosthesis is crucial for handling objects adequately. In the current paper we…
During development, epithelial tissues undergo extensive morphogenesis based on coordinated changes of cell shape and position over time. Continuum mechanics describes tissue mechanical state and shape changes in terms of strain and stress.…
We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models…
Photoelasticity is employed to investigate the stress state near stiff rectangular and rhombohedral inclusions embedded in a 'soft' elastic plate. Results show that the singular stress field predicted by the linear elastic solution for the…
Understanding the stress transfer mechanisms from a polymer matrix to two-dimensional reinforcements is essential for the preparation of high performance nanocomposites. In this study, the interfacial stress transfer from a flexible polymer…
Inferring latent dynamics from multivariate time-series defined over topological cell complexes is crucial for capturing the complex, higher-order interactions inherent in real-world systems such as in water, sensor, and transportation…
Knowing the stress within a soft material is of fundamental interest to basic research and practical applications, such as soft matter devices, biomaterial engineering, and medical sciences. However, it is challenging to measure stress…
We propose a meshless method to compute pressure fields from image velocimetry data, regardless of whether this is available on a regular grid as in cross-correlation based velocimetry or on scattered points as in tracking velocimetry. The…
Although understanding the collective migration of cells, such as that seen in epithelial sheets, is essential for understanding diseases such as metastatic cancer, this motion is not yet as well characterized as individual cell migration.…
We introduce the inverse Kalman filter, which enables exact matrix-vector multiplication between a covariance matrix from a dynamic linear model and any real-valued vector with linear computational cost. We integrate the inverse Kalman…
The present work introduces a novel numerical approach for the process modeling of fiber-reinforced thermoset polymers at the micro-scale level, that can be used to predict curing-induced residual stresses. The cure kinetics is described…
Mechanical forces such as fluid shear have been shown to enhance cell growth and differentiation, but knowledge of their mechanistic effect on cells is limited because the local flow patterns and associated metrics are not precisely known.…