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Palpation of human tissue during Minimally Invasive Surgery is hampered due to restricted access. In this extended abstract, we present a variable stiffness and dynamic force range sensor that has the potential to address this challenge.…

Medical Physics · Physics 2024-12-16 Abu Bakar Dawood , Zhenyu Zhang , Martin Angelmahr , Alberto Arezzo , Kaspar Althoefer

A consistent treatment of the coupling of surface energy and elasticity within the multi-phase- field framework is presented. The model accurately reproduces stress distribution in a number of analytically tractable, yet non-trivial, cases…

Mesoscale and Nanoscale Physics · Physics 2018-01-17 Raphael Schiedung , Ingo Steinbach , Fathollah Varnik

Living organisms have mastered the dynamic control of internal stresses to perform an array of functions, such as change shape and locomote. State-of-the-art attempts to replicate this ability in synthetic materials are rudimentary in…

Soft Condensed Matter · Physics 2021-02-16 Ido Levin , Robert Deegan , Eran Sharon

Simulations are used to examine the microscopic origins of strain hardening in polymer glasses. While traditional entropic network models can be fit to the total stress, their underlying assumptions are inconsistent with simulation results.…

Materials Science · Physics 2009-11-13 Robert S. Hoy , Mark O. Robbins

Mechanical metamaterials are usually designed to show desired responses to prescribed forces. In some applications, the desired force-response relationship might be hard to specify exactly, although examples of forces and corresponding…

Soft Condensed Matter · Physics 2020-11-10 Menachem Stern , Chukwunonso Arinze , Leron Perez , Stephanie Palmer , Arvind Murugan

Machine learning force fields possess unprecedented potential in achieving both accuracy and efficiency in molecular simulations. Nevertheless, their application in organic systems is often hindered by structural collapse during simulation…

Computational Physics · Physics 2026-02-03 Junbao Hu , Dingyu Hou , Jian Jiang

The study of cells' dynamical properties is essential to a better understanding of several physiological processes. These properties are directly associated with cells' mechanical parameters experimentally achieved through physical stress.…

Soft Condensed Matter · Physics 2022-01-26 G. Ourique , E. F. Teixeira , L. G. Brunnet

In video-records, objects moving in intracellular regions are often hardly detectable and identifiable. In order to squeeze the information on the intracellular flows, we propose an automatic method of reconstruction of intracellular flow…

Biological Physics · Physics 2022-01-13 Kirill Lonhus , Renata Rychtarikova , Ali Ghaznavi , Dalibor Stys

The constant interplay and information exchange between cells and their micro-environment are essential to their survival and ability to execute biological functions. To date, a few leading technologies such as traction force microscopy,…

Cell Behavior · Quantitative Biology 2023-06-29 Feng Xu , Shuxiang Zhang , Linjie Ma , Yong Hou , Jie Li , Andrej Denisenko , Zifu Li , Joachim Spatz , Jörg Wrachtrup , Qiang Wei , Zhiqin Chu

Development, regeneration and cancer involve drastic transitions in tissue morphology. In analogy with the behavior of inert fluids, some of these transitions have been interpreted as wetting transitions. The validity and scope of this…

This research enhances linear regression models by integrating a Kalman filter and analysing curve areas to minimize loss. The goal is to develop an optimal linear regression equation using stochastic gradient descent (SGD) for weight…

Machine Learning · Computer Science 2023-08-24 Gokulprasath R

Thin films or sheets subjected to external forces often undergo mechanical instability, leading to regular patterns of wrinkles, folds, and creases. As can be anticipated from the difficulty of flattening a curved globe, any natural…

Pattern Formation and Solitons · Physics 2025-02-13 Megha Emerse , Lucas Goehring

The design and operating of a portable holographic interferometer for residual stress analysis by creating a small scratch along with a new mathematical algorithm of calculations are discussed. Preliminary data of the stress investigations…

Actin and myosin assemble into a thin layer of a highly dynamic network underneath the membrane of eukaryotic cells. This network generates the forces that drive cell and tissue-scale morphogenetic processes. The effective material…

Biological Physics · Physics 2016-05-04 A. Saha , M. Nishikawa , M. Behrndt , C. -P. Heisenberg , F. Jülicher , S. W. Grill

Cross-sections of cell shapes in a tissue monolayer typically resemble a tiling of convex polygons. Yet, examples exist where the polygons are not convex with curved cell-cell interfaces, as seen in the adaxial epidermis. To date,…

Biological Physics · Physics 2024-06-21 Kyungeun Kim , J. M. Schwarz , Martine Ben Amar

In this paper we develop a mathematical model of the distribution of microwave electric field in heterogenous biological tissue of mammary gland. We use this model to investigate the efficiency of the medical diagnostic method based on…

Computational Physics · Physics 2017-10-10 Maxim Polyakov , Alexander Khoperskov , Andrey Svetlov

The tractions that cells exert on a gel substrate from the observed displacements is an increasingly attractive and valuable information in biomedical experiments. The computation of these tractions requires in general the solution of an…

Computational Physics · Physics 2016-08-30 Jose J Munoz

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

Mechanical properties of the tissue engineering scaffolds are known to play a crucial role in tissue regeneration. Here, we have utilized discrete network and finite element models to study fibrous scaffold mechanics and its dependence on…

Soft Condensed Matter · Physics 2025-01-15 Dhruba Jyoti Mech , Mohd Suhail Rizvi

We study the competition for space between two cell lines that differ only in the expression of the Ras oncogene. The two cell populations are initially separated and set to migrate antagonistically towards an in-between stripe of free…

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