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Multivariate statistics are often available as well as necessary in hypothesis tests. We study how to use such statistics to control not only false discovery rate (FDR) but also positive FDR (pFDR) with good power. We show that FDR can be…

Statistics Theory · Mathematics 2008-05-21 Zhiyi Chi

Multiple hypothesis testing, a situation when we wish to consider many hypotheses, is a core problem in statistical inference that arises in almost every scientific field. In this setting, controlling the false discovery rate (FDR), which…

Statistics Theory · Mathematics 2019-03-19 Shiyun Chen , Shiva Kasiviswanathan

High-dimensional variable selection, particularly in genomics, requires error-controlling procedures that scale to millions of predictors. The Terminating-Random Experiments (T-Rex) selector achieves false discovery rate (FDR) control by…

Methodology · Statistics 2026-04-10 Taulant Koka , Jasin Machkour , Daniel P. Palomar , Michael Muma

Deep generative models have become increasingly effective at producing realistic images from randomly sampled seeds, but using such models for controllable manipulation of existing images remains challenging. We propose the Swapping…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Taesung Park , Jun-Yan Zhu , Oliver Wang , Jingwan Lu , Eli Shechtman , Alexei A. Efros , Richard Zhang

The introduction of the false discovery rate (FDR) by Benjamini and Hochberg has spurred a great interest in developing methodologies to control the FDR in various settings. The majority of existing approaches, however, address the FDR…

Methodology · Statistics 2016-06-09 Kasra Alishahi , Ahmad Reza Ehyaei , Ali Shojaie

In real-world applications of reinforcement learning, it is often challenging to obtain a state representation that is parsimonious and satisfies the Markov property without prior knowledge. Consequently, it is common practice to construct…

Machine Learning · Statistics 2024-07-31 Tao Ma , Jin Zhu , Hengrui Cai , Zhengling Qi , Yunxiao Chen , Chengchun Shi , Eric B. Laber

Model bias is an inherent limitation of the current dominant approach to optimal quantum control, which relies on a system simulation for optimization of control policies. To overcome this limitation, we propose a circuit-based approach for…

Quantum Physics · Physics 2022-03-31 V. V. Sivak , A. Eickbusch , H. Liu , B. Royer , I. Tsioutsios , M. H. Devoret

In several physical systems, important properties characterizing the system itself are theoretically related with specific degrees of freedom. Although standard Monte Carlo simulations provide an effective tool to accurately reconstruct the…

High Energy Physics - Lattice · Physics 2017-05-29 Marco Cristoforetti , Giuseppe Jurman , Andrea I. Nardelli , Cesare Furlanello

Considering the knockoff-based multiple testing framework of Barber and Cand\`es [2015], we revisit the method of Sarkar and Tang [2022] and identify it as a specific case of an un-normalized e-value weighted Benjamini-Hochberg procedure.…

Methodology · Statistics 2026-02-13 Aniket Biswas , Aaditya Ramdas

Deep learning has become increasingly popular in both supervised and unsupervised machine learning thanks to its outstanding empirical performance. However, because of their intrinsic complexity, most deep learning methods are largely…

Machine Learning · Computer Science 2018-09-07 Yang Young Lu , Yingying Fan , Jinchi Lv , William Stafford Noble

Autoencoders and generative neural network models have recently gained popularity in fluid mechanics due to their spontaneity and low processing time instead of high fidelity CFD simulations. Auto encoders are used as model order reduction…

Fluid Dynamics · Physics 2022-03-04 Kanishk , Tanishk Nandal , Prince Tyagi , Raj Kumar Singh

False discovery rate (FDR) is a cornerstone of modern multiple testing. However, it often fails to guarantee the reliability of "marginal" discoveries that lie at the boundary of the rejection set, which are often crucial in high-precision…

Methodology · Statistics 2026-05-12 Yifan Zhang , Wentao Zhang , Changliang Zou , Haojie Ren

High-dimensional longitudinal time series data is prevalent across various real-world applications. Many such applications can be modeled as regression problems with high-dimensional time series covariates. Deep learning has been a popular…

Machine Learning · Statistics 2024-04-09 Wenxuan Zuo , Zifan Zhu , Yuxuan Du , Yi-Chun Yeh , Jed A. Fuhrman , Jinchi Lv , Yingying Fan , Fengzhu Sun

Deep generative modeling to stochastically design small molecules is an emerging technology for accelerating drug discovery and development. However, one major issue in molecular generative models is their lower frequency of drug-like…

We study the problem of estimating the optimal Q-function of $\gamma$-discounted Markov decision processes (MDPs) under the synchronous setting, where independent samples for all state-action pairs are drawn from a generative model at each…

Machine Learning · Statistics 2025-05-27 Mohammad Boveiri , Peyman Mohajerin Esfahani

Conventional multiple testing procedures often assume hypotheses for different features are exchangeable. However, in many scientific applications, additional covariate information regarding the patterns of signals and nulls are available.…

Methodology · Statistics 2020-06-12 Xianyang Zhang , Jun Chen

We apply the knockoff procedure to factor selection in finance. By building fake but realistic factors, this procedure makes it possible to control the fraction of false discovery in a given set of factors. To show its versatility, we apply…

Statistical Finance · Quantitative Finance 2021-07-07 Damien Challet , Christian Bongiorno , Guillaume Pelletier

Quantum devices need precise control to achieve their full capability. In this work, we address the problem of controlling closed quantum systems, tackling two main issues. First, in practice the control signals are usually subject to…

Quantum Physics · Physics 2024-07-16 Ahmed F. Fouad , Akram Youssry , Ahmed El-Rafei , Sherif Hammad

Urban autonomous driving decision making is challenging due to complex road geometry and multi-agent interactions. Current decision making methods are mostly manually designing the driving policy, which might result in sub-optimal solutions…

Machine Learning · Computer Science 2019-10-23 Jianyu Chen , Bodi Yuan , Masayoshi Tomizuka

As new Model-X knockoff construction techniques are developed, primarily concerned with determining the correct conditional distribution from which to sample, we focus less on deriving the correct multivariate distribution and instead ask…

Methodology · Statistics 2025-02-05 Christopher Hemmens , Stephan Robert-Nicoud
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