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Process Planning and Scheduling (PPS) is an essential and practical topic but a very intractable problem in manufacturing systems. Many research use iterative methods to solve such problems; however, they cannot achieve satisfactory results…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-18 Kai Sun

Quantitative myocardial perfusion mapping has advantages over qualitative assessment, including the ability to detect global flow reduction. However, it is not clinically available and remains as a research tool. Building upon the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-17 Hui Xue , Louise A. E. Brown , Sonia Nielles-Vallespin , Sven Plein , Peter Kellman

Large language models (LLMs) demonstrate impressive performance but lack the flexibility to adapt to human preferences quickly without retraining. In this work, we introduce Test-time Preference Optimization (TPO), a framework that aligns…

Computation and Language · Computer Science 2025-01-23 Yafu Li , Xuyang Hu , Xiaoye Qu , Linjie Li , Yu Cheng

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

Quantitative Methods · Quantitative Biology 2024-09-19 Qingqing Wang , Chang Chang

Current inverse treatment planning methods that optimize both catheter positions and dwell times in prostate HDR brachytherapy use surrogate linear or quadratic objective functions that have no direct interpretation in terms of dose-volume…

Medical Physics · Physics 2014-08-13 Bram L. Gorissen , Dick den Hertog , Aswin L. Hoffmann

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

Human-Computer Interaction · Computer Science 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

Medical Physics · Physics 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

In this work we demonstrate how to automate parts of the infectious disease-control policy-making process via performing inference in existing epidemiological models. The kind of inference tasks undertaken include computing the posterior…

Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…

The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostatic lesion (DIL) boost represents a significant advancement in…

The advent of Large Language Models (LLMs) has created new opportunities for the automation of scientific research spanning both experimental processes and computational simulations. This study explores the feasibility of constructing an…

Artificial Intelligence · Computer Science 2025-01-16 Zhihan Liu , Yubo Chai , Jianfeng Li

An important challenge confronting healthcare is the effective management of access to primary care. Robust appointment scheduling policies/templates can help strike an effective balance between the lead-time to an appointment (a.k.a.…

Optimization and Control · Mathematics 2019-11-14 Sina Faridimehr , Saravanan Venkatachalam , Ratna Babu Chinnam

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

Medical Physics · Physics 2015-06-15 Hamed Yarmand , David Craft

Supervised fine-tuning (SFT) is a common method to enhance the tool calling capabilities of Large Language Models (LLMs), with the training data often being synthesized. The current data synthesis process generally involves sampling a set…

Computation and Language · Computer Science 2025-03-18 Zezhong Wang , Xingshan Zeng , Weiwen Liu , Liangyou Li , Yasheng Wang , Lifeng Shang , Xin Jiang , Qun Liu , Kam-Fai Wong

Recently, many techniques have been introduced that allow the (automated) classification of the runtime complexity of term rewrite systems (TRSs for short). In earlier work, the authors have shown that for confluent TRSs, innermost…

Computational Complexity · Computer Science 2011-06-09 Martin Avanzini , Georg Moser

Accurate 3D dose calculation for Pencil Beam Scanning Proton Therapy (PBSPT) is typically performed with Monte Carlo (MC) engines, but their runtimes limit adaptive workflows and repeated evaluations. Current deep-learning proton dose…

Medical Physics · Physics 2026-02-19 Mikołaj Stryja , Danny Lathouwers , Zoltán Perkó

A novel dose calculation approach was designed based on the application of LSTM network that processes the 3D patient/phantom geometry as a sequence of 2D computed tomography input slices yielding a corresponding sequence of 2D slices that…

Medical Physics · Physics 2021-06-09 Ahmad Neishabouri , Niklas Wahl , Ulrich Köthe , Mark Bangert

Large language models (LLMs) have demonstrated exceptional reasoning capabilities, enabling them to solve various complex problems. Recently, this ability has been applied to the paradigm of tool learning. Tool learning involves providing…

Artificial Intelligence · Computer Science 2025-08-18 Yanming Liu , Xinyue Peng , Jiannan Cao , Yuwei Zhang , Xuhong Zhang , Sheng Cheng , Xun Wang , Jianwei Yin , Tianyu Du

A platform trial with a master protocol provides an infrastructure to ethically and efficiently evaluate multiple treatment options in multiple diseases. Given that certain study drugs can enter or exit a platform trial, the randomization…

Methodology · Statistics 2025-07-15 Tianyu Zhan , Jane Zhang , Lei Shu , Yihua Gu

Inspection planning, the task of planning motions that allow a robot to inspect a set of points of interest, has applications in domains such as industrial, field, and medical robotics. Inspection planning can be computationally…

Robotics · Computer Science 2019-07-02 Mengyu Fu , Alan Kuntz , Oren Salzman , Ron Alterovitz