Related papers: Automatizing a non-scripting TPS for optimizing cl…
Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…
Molecular dynamics (MD) simulations are widely used to study large-scale molecular systems. HPC systems are ideal platforms to run these studies, however, reaching the necessary simulation timescale to detect rare processes is challenging,…
Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…
Reverse time migration (RTM) is an algorithm widely used in the oil and gas industry to process seismic data. It is a computationally intensive task that suits well in parallel computers. Methods such as RTM can be parallelized in shared…
Automatic Text Summarization (ATS), utilizing Natural Language Processing (NLP) algorithms, aims to create concise and accurate summaries, thereby significantly reducing the human effort required in processing large volumes of text. ATS has…
This paper proposes an efficient and semi-automated method for human-in-the-loop post-editing for machine translation (MT) corpus generation. The method is based on online training of a custom MT quality estimation metric on-the-fly as…
BACKGROUND: Radiology reports are typically written in a free-text format, making clinical information difficult to extract and use. Recently the adoption of structured reporting (SR) has been recommended by various medical societies thanks…
We propose an anatomically-informed initialisation method for interpatient CT non-rigid registration (NRR), using a learning-based model to estimate correspondences between organ structures. A thin plate spline (TPS) deformation, set up…
We present an optimization-based approach to radiation treatment planning over time. Our approach formulates treatment planning as an optimal control problem with nonlinear patient health dynamics derived from the standard linear-quadratic…
Pre-trained Language Models (PLMs), such as ChatGPT, have significantly advanced the field of natural language processing. This progress has inspired a series of innovative studies that explore the adaptation of PLMs to time series…
Performance, power, and area (PPA) optimization is a fundamental task in RTL design, requiring a precise understanding of circuit functionality and the relationship between circuit structures and PPA metrics. Recent studies attempt to…
Purpose: A Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) are presented for a modified ultra-high dose-rate electron FLASH radiotherapy (eFLASH-RT) LINAC. Methods: The gantry…
Recent advances in large language models (LLMs) have sparked growing interest in automatic RTL optimization for better performance, power, and area (PPA). However, existing methods are still far from realistic RTL optimization. Their…
The automation of ab initio simulations is essential in view of performing high-throughput (HT) computational screenings oriented to the discovery of novel materials with desired physical properties. In this work, we propose algorithms and…
In this work, we address the Text-to-Speech (TTS) task by proposing a non-autoregressive architecture called EfficientTTS. Unlike the dominant non-autoregressive TTS models, which are trained with the need of external aligners, EfficientTTS…
Development of Cyber Physical Systems (CPSs) requires close interaction between developers with expertise in many domains to achieve ever-increasing demands for improved performance, reduced cost, and more system autonomy. Each engineering…
Minimally invasive colorectal surgery is characterized by procedural variability, a difficult learning curve, and complications that impact quality and outcomes. Video-based assessment (VBA) offers an opportunity to generate data-driven…
Fluence map optimization for intensity-modulated radiation therapy planning can be formulated as a large-scale inverse problem with competing objectives and constraints associated with the tumors and organs-at-risk. Unfortunately,…
Purpose: We present a framework for robust automated treatment planning using machine learning, comprising scenario-specific dose prediction and robust dose mimicking. Methods: The scenario dose prediction pipeline is divided into the…
Chemotherapy appointment scheduling is a challenging problem due to the uncertainty in pre-medication and infusion durations. In this paper, we formulate a two-stage stochastic mixed integer programming model for the chemotherapy…