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The R Package IBMPopSim aims to simulate the random evolution of heterogeneous populations using stochastic Individual-Based Models (IBMs). The package enables users to simulate population evolution, in which individuals are characterized…

Populations and Evolution · Quantitative Biology 2024-02-28 Daphné Giorgi , Sarah Kaakai , Vincent Lemaire

Personalised medicine strives to identify the right treatment for the right patient at the right time, integrating different types of biological and environmental information. Such information come from a variety of sources: omics data…

Applications · Statistics 2014-01-14 Marco Scutari

Diversity measurement underpins the study of biological systems, but measures used vary across disciplines. Despite their common use and broad utility, no unified framework has emerged for measuring, comparing and partitioning diversity.…

Quantitative Methods · Quantitative Biology 2016-12-09 Richard Reeve , Tom Leinster , Christina A. Cobbold , Jill Thompson , Neil Brummitt , Sonia N. Mitchell , Louise Matthews

Deriving insights from high-dimensional data is one of the core problems in data mining. The difficulty mainly stems from the fact that there are exponentially many variable combinations to potentially consider, and there are infinitely…

Machine Learning · Statistics 2021-11-08 Jefrey Lijffijt , Bo Kang , Wouter Duivesteijn , Kai Puolamäki , Emilia Oikarinen , Tijl De Bie

Randomized experimentation (also known as A/B testing or bucket testing) is widely used in the internet industry to measure the metric impact obtained by different treatment variants. A/B tests identify the treatment variant showing the…

AI models for medical diagnosis often exhibit uneven performance across patient populations due to heterogeneity in disease prevalence, imaging appearance, and clinical risk profiles. Existing algorithmic fairness approaches typically seek…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Gelei Xu , Yuying Duan , Jun Xia , Ruining Deng , Wei Jin , Yiyu Shi

Object re-identification is of increasing importance in visual surveillance. Most existing works focus on re-identify individual from multiple cameras while the application of group re-identification (Re-ID) is rarely discussed. We redefine…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Hao Xiao

'Optimal cutpoints' for binary classification tasks are often established by testing which cutpoint yields the best discrimination, for example the Youden index, in a specific sample. This results in 'optimal' cutpoints that are highly…

Computation · Statistics 2020-02-24 Christian Thiele , Gerrit Hirschfeld

This research presents a novel multimodal data fusion methodology for pain behavior recognition, integrating statistical correlation analysis with human-centered insights. Our approach introduces two key innovations: 1) integrating…

Artificial Intelligence · Computer Science 2025-01-22 Xingrui Gu , Zhixuan Wang , Irisa Jin , Zekun Wu

There is an ongoing debate on personalization, adapting results to the unique user exploiting a user's personal history, versus customization, adapting results to a group profile sharing one or more characteristics with the user at hand.…

Information Retrieval · Computer Science 2016-09-05 Mostafa Dehghani , Hosein Azarbonyad , Jaap Kamps , Maarten Marx

Triple difference designs have become increasingly popular in empirical economics. The advantage of a triple difference design is that, within a treatment group, it allows for another subgroup of the population -- potentially less impacted…

Econometrics · Economics 2025-06-04 Laura Caron

We consider the problem of selecting the optimal subgroup to treat when data on covariates is available from a randomized trial or observational study. We distinguish between four different settings including (i) treatment selection when…

Methodology · Statistics 2018-02-28 Tyler J. VanderWeele , Alex R. Luedtke , Mark J. van der Laan , Ronald C. Kessler

Conducting research often involves managing multiple disconnected tools for survey design, data collection, response analysis, and report generation, leading to inefficiencies, increased error risks, and challenges in ensuring…

Computation · Statistics 2025-08-11 Clievins Selva

Robust estimation provides essential tools for analyzing data that contain outliers, ensuring that statistical models remain reliable even in the presence of some anomalous data. While robust methods have long been available in R, users of…

Computation · Statistics 2024-11-05 Sarah Leyder , Jakob Raymaekers , Peter J. Rousseeuw , Thomas Servotte , Tim Verdonck

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…

Quantitative Methods · Quantitative Biology 2022-03-01 Lingsong Meng , Dorina Avram , George Tseng , Zhiguang Huo

The performance of optimization algorithms relies crucially on their parameterizations. Finding good parameter settings is called algorithm tuning. The sequential parameter optimization (SPOT) package for R is a toolbox for tuning and…

Mathematical Software · Computer Science 2021-03-05 Thomas Bartz-Beielstein , Martin Zaefferer , Frederik Rehbach

Recent advances in cryptography promise to enable secure statistical computation on encrypted data, whereby a limited set of operations can be carried out without the need to first decrypt. We review these homomorphic encryption schemes in…

Machine Learning · Statistics 2015-08-27 Louis J. M. Aslett , Pedro M. Esperança , Chris C. Holmes

Estimation of heterogeneous treatment effects is an active area of research. Most of the existing methods, however, focus on estimating the conditional average treatment effects of a single, binary treatment given a set of pre-treatment…

Methodology · Statistics 2025-05-30 Max Goplerud , Kosuke Imai , Nicole E. Pashley

We extend a general approach to evaluating identification risk of synthesized variables in partially synthetic data. For multiple continuous synthesized variables, we introduce the use of a radius $r$ in the construction of identification…

Methodology · Statistics 2021-04-07 Ryan Hornby , Jingchen Hu

There is increasing interest in combining information from experimental studies, including randomized and single-group trials, with information from external experimental or observational data sources. Such efforts are usually motivated by…

Methodology · Statistics 2026-04-23 Lawson Ung , Guanbo Wang , Sebastien Haneuse , Miguel A. Hernán , Issa J. Dahabreh