Personalised medicine strives to identify the right treatment for the right patient at the right time, integrating different types of biological and environmental information. Such information come from a variety of sources: omics data (genomic, proteomic, metabolomic, etc.), live molecular diagnostics, and other established diagnostics routinely used by medical doctors. Integrating these different kinds of data, which are all high-dimensional, presents significant challenges in knowledge representation and subsequent reasoning. The ultimate goal of such a modelling effort is to elucidate the flow of information that links genes, protein signalling and other physiological responses to external stimuli such as environmental conditions or the progress of a disease.
@article{arxiv.1401.2649,
title = {Personalised Medicine: Taking a New Look at the Patient},
author = {Marco Scutari},
journal= {arXiv preprint arXiv:1401.2649},
year = {2014}
}
Comments
Workshop on Foundations of Biomedical Knowledge Representation, October 29 - November 2, 2012 Leiden, The Netherlands