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In statistics, series of ordinary least squares problems (OLS) are used to study the linear correlation among sets of variables of interest; in many studies, the number of such variables is at least in the millions, and the corresponding…

Computational Engineering, Finance, and Science · Computer Science 2015-04-30 Alvaro Frank , Diego Fabregat-Traver , Paolo Bientinesi

We present a comprehensive framework for applying rigorous statistical techniques from econometrics to analyze and improve machine learning systems. We introduce key statistical methods such as Ordinary Least Squares (OLS) regression,…

Machine Learning · Computer Science 2024-10-03 Michaël Soumm

To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatment status using an instrumental variable (IV) and conducts…

Methodology · Statistics 2026-04-03 Anqi Zhao , Peng Ding , Fan Li

Two-stage least squares (TSLS) estimators and variants thereof are widely used to infer the effect of an exposure on an outcome using instrumental variables (IVs). They belong to a wider class of two-stage IV estimators, which are based on…

Methodology · Statistics 2015-10-08 Stijn Vansteelandt , Vanessa Didelez

This paper introduces a new fixed effects estimator for linear panel data models with clustered time patterns of unobserved heterogeneity. The method avoids non-convex and combinatorial optimization by combining a preliminary consistent…

Econometrics · Economics 2025-04-21 Martin Mugnier

Consider the case that one observes a single time-series, where at each time t one observes a data record O(t) involving treatment nodes A(t), possible covariates L(t) and an outcome node Y(t). The data record at time t carries information…

Statistics Theory · Mathematics 2021-02-04 Mark J. van der Laan , Ivana Malenica

State-level policy evaluations commonly employ a difference-in-differences (DID) study design; yet within this framework, statistical model specification varies notably across studies. Motivated by applied state-level opioid policy…

An Orthogonal Least Squares (OLS) based feature selection method is proposed for both binomial and multinomial classification. The novel Squared Orthogonal Correlation Coefficient (SOCC) is defined based on Error Reduction Ratio (ERR) in…

Machine Learning · Computer Science 2021-11-09 Sikai Zhang , Zi-Qiang Lang

The statistical essence of the Transformer architecture has long remained elusive: Is it a universal approximator, or a neural network version of known computational algorithms? Through rigorous algebraic proof, we show that the latter…

Machine Learning · Computer Science 2026-04-16 Xiaojun Tan , Yuchen Zhao

Instrumental variables are widely used to deal with unmeasured confounding in observational studies and imperfect randomized controlled trials. In these studies, researchers often target the so-called local average treatment effect as it is…

Methodology · Statistics 2022-03-24 Linbo Wang , Yuexia Zhang , Thomas S. Richardson , James M. Robins

Ordinary differential equations (ODEs) can provide mechanistic models of temporally local changes of processes, where parameters are often informed by external knowledge. While ODEs are popular in systems modeling, they are less established…

Methodology · Statistics 2025-07-10 Maren Hackenberg , Astrid Pechmann , Clemens Kreutz , Janbernd Kirschner , Harald Binder

Beta coefficients for linear regression models represent the ideal form of an interpretable feature effect. However, for non-linear models and especially generalized linear models, the estimated coefficients cannot be interpreted as a…

Machine Learning · Computer Science 2022-01-24 Christian A. Scholbeck , Giuseppe Casalicchio , Christoph Molnar , Bernd Bischl , Christian Heumann

Longitudinal studies with binary or ordinal responses are widely encountered in various disciplines, where the primary focus is on the temporal evolution of the probability of each response category. Traditional approaches build from the…

Methodology · Statistics 2024-09-04 Jizhou Kang , Athanasios Kottas

Deep learning research has uncovered the phenomenon of benign overfitting for overparameterized statistical models, which has drawn significant theoretical interest in recent years. Given its simplicity and practicality, the ordinary least…

Statistics Theory · Mathematics 2024-05-31 Dennis Shen , Dogyoon Song , Peng Ding , Jasjeet S. Sekhon

We consider linear structural equation models that are associated with mixed graphs. The structural equations in these models only involve observed variables, but their idiosyncratic error terms are allowed to be correlated and…

Computation · Statistics 2017-10-10 Y. Samuel Wang , Mathias Drton

We analyze linear panel regression models with interactive fixed effects and predetermined regressors, for example lagged-dependent variables. The first-order asymptotic theory of the least squares (LS) estimator of the regression…

Econometrics · Economics 2026-05-04 Hyungsik Roger Moon , Martin Weidner

By exploiting McFadden (1974)'s results on conditional logit estimation, we show that there exists a one-to-one mapping between existence and uniqueness of conditional maximum likelihood estimates of the binary logit model with fixed…

Econometrics · Economics 2020-09-30 Martin Mugnier

Sparse linear regression, which entails finding a sparse solution to an underdetermined system of linear equations, can formally be expressed as an $l_0$-constrained least-squares problem. The Orthogonal Least-Squares (OLS) algorithm…

Machine Learning · Statistics 2016-08-01 Abolfazl Hashemi , Haris Vikalo

Log-linear models are a classical tool for the analysis of contingency tables. In particular, the subclass of graphical log-linear models provides a general framework for modelling conditional independences. However, with the exception of…

Statistics Theory · Mathematics 2010-03-04 Mathias Drton , Thomas S. Richardson

Finite mixture models are widely used in econometric analyses to capture unobserved heterogeneity. This paper shows that maximum likelihood estimation of finite mixtures of parametric densities can suffer from substantial finite-sample bias…

Methodology · Statistics 2026-02-04 Raphaël Langevin