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The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known functional modules. However, how the modular topology of the molecular…

Molecular Networks · Quantitative Biology 2007-09-07 Jing Zhao , Guo-Hui Ding , Lin Tao , Hong Yu , Zhong-Hao Yu , Jian-Hua Luo , Zhi-Wei Cao , Yi-Xue Li

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

Neurons and Cognition · Quantitative Biology 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

Signal Processing · Electrical Eng. & Systems 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

Ego-networks are fundamental structures in social graphs, yet the process of their evolution is still widely unexplored. In an online context, a key question is how link recommender systems may skew the growth of these networks, possibly…

Social and Information Networks · Computer Science 2017-02-07 Luca Maria Aiello , Nicola Barbieri

Identifying the hidden organizational principles and relevant structures of networks representing complex physical systems is fundamental to understand their properties. To this aim, uncovering the structures involving a network's prominent…

Physics and Society · Physics 2022-08-17 Nicola Pedreschi , Demian Battaglia , Alain Barrat

The connectome describes the complete set of synaptic contacts through which neurons communicate. While the architecture of the $\textit{C. elegans}$ connectome has been extensively characterized, much less is known about the organization…

Neurons and Cognition · Quantitative Biology 2025-09-18 Sophie Dvali , Caio Seguin , Richard Betzel , Andrew M. Leifer

Human brain maturation is characterized by the prolonged development of structural and functional properties of large-scale networks that extends into adulthood. However, it is not clearly understood which features change and which remain…

Neurons and Cognition · Quantitative Biology 2014-04-02 Sol Lim , Cheol E. Han , Peter J. Uhlhaas , Marcus Kaiser

The emergence of detailed maps of physical networks, like the brain connectome, vascular networks, or composite networks in metamaterials, whose nodes and links are physical entities, have demonstrated the limits of the current network…

The dynamic characteristics of functional network connectivity have been widely acknowledged and studied. Both shared and unique information has been shown to be present in the connectomes. However, very little has been known about whether…

Neurons and Cognition · Quantitative Biology 2020-06-18 Biao Cai , Gemeng Zhang , Aiying Zhang , Li Xiao , Wenxing Hu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

Rich-club ordering refers to the tendency of nodes with a high degree to be more interconnected than expected. In this paper we consider the concept of rich-club ordering when generalized to structural measures that differ from the node…

Physics and Society · Physics 2019-02-21 Matteo Cinelli

Modern neuroimaging technologies, combined with state-of-the-art data processing pipelines, have made it possible to collect longitudinal observations of an individual's brain connectome at different ages. It is of substantial scientific…

Applications · Statistics 2019-08-16 Lu Wang , Zhengwu Zhang

Brain networks can be defined and explored through their connectivity. Here, we analyzed the relationship between structural connectivity (SC) across 2,514 regions that cover the entire brain and brainstem, and their dynamic functional…

Recent studies uncovered important core/periphery network structures characterizing complex sets of cooperative and competitive interactions between network nodes, be they proteins, cells, species or humans. Better characterization of the…

Physics and Society · Physics 2013-12-03 Peter Csermely , Andras London , Ling-Yun Wu , Brian Uzzi

Recent studies have demonstrated the existence of community structure and rich club nodes, (i.e., highly interconnected, high degree hub nodes), in human brain functional networks. The cognitive relevance of the detected modules and hubs…

Social and Information Networks · Computer Science 2014-07-08 S. Sarkar , S. Chawla , H. Weng

For more than a century, cerebral cartography has been driven by investigations of structural and morphological properties of the brain across spatial scales and the temporal/functional phenomena that emerge from these underlying features.…

Neurons and Cognition · Quantitative Biology 2016-05-06 Leonardo L. Gollo , Andrew Zalesky , R. Matthew Hutchison , Martijn van den Heuvel , Michael Breakspear

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

Neurons and Cognition · Quantitative Biology 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca