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Principles of network topology have been widely studied in the human connectome. Of particular interest is the modularity of the human brain, where the connectome is divided into subnetworks and subsequently changes with development, aging…

Neurons and Cognition · Quantitative Biology 2019-02-05 Markus D. Schirmer , Ai Wern Chung , P. Ellen Grant , Natalia S. Rost

The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the…

Neurons and Cognition · Quantitative Biology 2018-11-01 Gorka Zamora-López , Yuhan Chen , Gustavo Deco , Morten L. Kringelbach , Changsong Zhou

Brain development during adolescence is marked by substantial changes in brain structure and function, leading to a stable network topology in adulthood. However, most prior work has examined the data through the lens of brain areas…

Quantitative Methods · Quantitative Biology 2016-12-26 Shi Gu , Muzhi Yang , John D. Medaglia , Ruben C. Gur , Raquel E. Gur , Theodore D. Satterthwaite , Danielle S. Bassett

Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a…

Neurons and Cognition · Quantitative Biology 2015-12-15 Alistair Perry , Wei Wen , Anton Lord , Anbupalam Thalamuthu , Perminder Sachdev , Michael Breakspear

The diffused nature of mild traumatic brain injury (mTBI) impacts brain white-matter pathways with potentially long-term consequences, even after initial symptoms have resolved. To understand post-mTBI recovery in adolescents, longitudinal…

Neurons and Cognition · Quantitative Biology 2019-12-13 Ai Wern Chung , Rebekah Mannix , Henry A. Feldman , P. Ellen Grant , Kiho Im

With distinct advantages in power over behavioral phenotypes, brain imaging traits have become emerging endophenotypes to dissect molecular contributions to behaviors and neuropsychiatric illnesses. Among different imaging features, brain…

Applications · Statistics 2022-12-05 Yize Zhao , Changgee Chang , Jingwen Zhang , Zhengwu Zhang

A core is said to be a group of central and densely connected nodes which governs the overall behavior of a network. Profiling this meso--scale structure currently relies on a limited number of methods which are often complex, and have…

Physics and Society · Physics 2015-08-19 Athen Ma , Raul J Mondragon

Biological neural networks are shaped both by evolution across generations and by individual learning within an organism's lifetime, whereas standard artificial neural networks undergo a single, large training procedure without inherited…

Machine Learning · Computer Science 2025-05-01 Klemen Kotar , Greta Tuckute

Core-periphery networks are structures that present a set of central and densely connected nodes, namely the core, and a set of non-central and sparsely connected nodes, namely the periphery. The rich-club refers to a set in which the…

Social and Information Networks · Computer Science 2017-08-25 Matteo Cinelli , Giovanna Ferraro , Antonio Iovanella

Many scale-free networks exhibit a rich club structure, where high degree vertices form tightly interconnected subgraphs. In this paper, we explore the emergence of rich clubs in the context of shortest path based centrality metrics. We…

Social and Information Networks · Computer Science 2018-08-10 Soumya Sarkar , Animesh Mukherjee , Sanjukta Bhowmick

The human brain is liable to undergo substantial alterations, anatomically and functionally with aging. Cognitive brain aging can either be healthy or degenerative in nature. Such degeneration of cognitive ability can lead to disorders such…

Signal Processing · Electrical Eng. & Systems 2022-06-17 Prerna Singh , Tapan Kumar Gandhi , Lalan Kumar

Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

Neurons and Cognition · Quantitative Biology 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López

How self-organized networks develop, mature and degenerate is a key question for sociotechnical, cyberphysical and biological systems with potential applications from tackling violent extremism through to neurological diseases. So far, it…

Physics and Society · Physics 2017-06-05 M. Zheng , Z. Cao , Y. Vorobyeva , P. Manrique , C. Song , N. F. Johnson

The human brain is organized into large-scale functional modules that have been shown to evolve in childhood and adolescence. However, it remains unknown whether structural brain networks are similarly refined during development,…

Traditionally, there is no evidence suggesting that there are strong ties between the rich-club property and the function of complex networks. In this study, we find that whether a very small portion of rich nodes connected to each other or…

Physics and Society · Physics 2015-05-28 Xiao-ke xu , Jie Zhang , Ping Li , Michael Small

The human structural connectome has a complex internal community organization, characterized by a high degree of overlap and related to functional and cognitive phenomena. We explored connectivity properties in connectome networks and…

Disordered Systems and Neural Networks · Physics 2025-02-24 V. Tiselko , O. Dogonasheva , A. Myshkin , O. Valba

The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

Neurons and Cognition · Quantitative Biology 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

The rich club organization (the presence of highly connected hub core in a network) influences many structural and functional characteristics of networks including topology, the efficiency of paths and distribution of load. Despite its…

Physics and Society · Physics 2017-12-05 Máté Csigi , Attila Kőrösi , József Bíró , Zalán Heszberger , Yury Malkov , András Gulyás

Uncovering the hidden regularities and organizational principles of networks arising in physical systems ranging from the molecular level to the scale of large communication infrastructures is the key issue for the understanding of their…

Data Analysis, Statistics and Probability · Physics 2015-06-26 Vittoria Colizza , Alessandro Flammini , M. Angeles Serrano , Alessandro Vespignani
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