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Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain…

Artificial Intelligence · Computer Science 2025-02-04 Song Wang , Zhenyu Lei , Zhen Tan , Jiaqi Ding , Xinyu Zhao , Yushun Dong , Guorong Wu , Tianlong Chen , Chen Chen , Aiying Zhang , Jundong Li

We propose Deep Feature Factorization (DFF), a method capable of localizing similar semantic concepts within an image or a set of images. We use DFF to gain insight into a deep convolutional neural network's learned features, where we…

Machine Learning · Computer Science 2018-10-09 Edo Collins , Radhakrishna Achanta , Sabine Süsstrunk

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

Quantitative Methods · Quantitative Biology 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Multi-task and multi-domain learning methods seek to learn multiple tasks/domains, jointly or one after another, using a single unified network. The primary challenge and opportunity lie in leveraging shared information across these tasks…

Machine Learning · Computer Science 2026-02-03 Yash Garg , Nebiyou Yismaw , Rakib Hyder , Ashley Prater-Bennette , M. Salman Asif

Predicting disease states from functional brain connectivity is critical for the early diagnosis of severe neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease. Existing studies commonly employ Graph Neural…

Machine Learning · Computer Science 2025-04-22 David Yang , Mostafa Abdelmegeed , John Modl , Minjeong Kim

Objective: In recent years, the functional connectivity of the human brain has been studied with graph theoretical tools. One such approach is community detection which is fundamental for uncovering the localized networks. Existing methods…

Signal Processing · Electrical Eng. & Systems 2022-09-27 Abdullah Karaaslanli , Meiby Ortiz-Bouza , Tamanna T. K. Munia , Selin Aviyente

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Deep learning has been widely used for hyperspectral pixel classification due to its ability of generating deep feature representation. However, how to construct an efficient and powerful network suitable for hyperspectral data is still…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Jingzhou Chen , Siyu Chen , Peilin Zhou , Yuntao Qian

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

A key question in brain sciences is how to identify time-evolving functional connectivity, such as that obtained from recordings of neuronal activity over time. We wish to explain the observed phenomena in terms of latent states which, in…

Methodology · Statistics 2026-05-14 Yiwei Gong , Susanna B. Mierau , Sinead A. Williamson

This work contributes to the development of a new data-driven method (D-DM) of feedforward neural networks (FNNs) learning. This method was proposed recently as a way of improving randomized learning of FNNs by adjusting the network…

Machine Learning · Computer Science 2021-07-07 Grzegorz Dudek

Nonnegative Matrix Factorization (NMF) is the problem of approximating a nonnegative matrix with the product of two low-rank nonnegative matrices and has been shown to be particularly useful in many applications, e.g., in text mining, image…

Optimization and Control · Mathematics 2012-08-13 Nicolas Gillis , François Glineur

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

In this paper we introduce a new hierarchical model for the simultaneous detection of brain activation and estimation of the shape of the hemodynamic response in multi-subject fMRI studies. The proposed approach circumvents a major…

Applications · Statistics 2015-11-13 David Degras , Martin A. Lindquist

We present a novel deep learning framework that uses dynamic functional connectivity to simultaneously localize the language and motor areas of the eloquent cortex in brain tumor patients. Our method leverages convolutional layers to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-18 Naresh Nandakumar , Niharika Shimona D'souza , Komal Manzoor , Jay J. Pillai , Sachin K. Gujar , Haris I. Sair , Archana Venkataraman

Functional brain network analysis has become an indispensable tool for brain disease analysis. It is profoundly impacted by deep learning methods, which can characterize complex connections between ROIs. However, the research on foundation…

Image and Video Processing · Electrical Eng. & Systems 2025-08-08 Yifei Tang , Hongjie Jiang , Changhong Jing , Hieu Pham , Shuqiang Wang

Nonnegative matrix factorization can be used to automatically detect topics within a corpus in an unsupervised fashion. The technique amounts to an approximation of a nonnegative matrix as the product of two nonnegative matrices of lower…

Computation and Language · Computer Science 2022-12-21 Michael R. Lindstrom , Xiaofu Ding , Feng Liu , Anand Somayajula , Deanna Needell

Supervised matrix factorization (SMF) is a classical machine learning method that simultaneously seeks feature extraction and classification tasks, which are not necessarily a priori aligned objectives. Our goal is to use SMF to learn…

Machine Learning · Statistics 2023-11-21 Joowon Lee , Hanbaek Lyu , Weixin Yao

We present a structured matrix factorization approach to analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and…

Neurons and Cognition · Quantitative Biology 2014-09-11 Eftychios A. Pnevmatikakis , Yuanjun Gao , Daniel Soudry , David Pfau , Clay Lacefield , Kira Poskanzer , Randy Bruno , Rafael Yuste , Liam Paninski
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