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Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

The scale of functional magnetic resonance image data is rapidly increasing as large multi-subject datasets are becoming widely available and high-resolution scanners are adopted. The inherent low-dimensionality of the information in this…

Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However,…

Machine Learning · Computer Science 2026-03-11 Jingfeng Tang , Peng Cao , Guangqi Wen , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Non-negative matrix factorization (NMF) is a fundamental matrix decomposition technique that is used primarily for dimensionality reduction and is increasing in popularity in the biological domain. Although finding a unique NMF is generally…

Information Theory · Computer Science 2021-08-23 Rami Nasser , Yonina C. Eldar , Roded Sharan

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Non-negative Matrix Factorization (NMF) has proven to be a powerful unsupervised learning method for uncovering hidden features in complex and noisy data sets with applications in data mining, text recognition, dimension reduction, face…

Background: Mining gene modules from genomic data is an important step to detect gene members of pathways or other relations such as protein-protein interactions. In this work, we explore the plausibility of detecting gene modules by…

Machine Learning · Computer Science 2017-05-12 YaoGong Zhang , YingJie Xu , Xin Fan , YuXiang Hong , Jiahui Liu , ZhiCheng He , YaLou Huang , MaoQiang Xie

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

Neuronal circuits formed in the brain are complex with intricate connection patterns. Such complexity is also observed in the retina as a relatively simple neuronal circuit. A retinal ganglion cell receives excitatory inputs from neurons in…

Neurons and Cognition · Quantitative Biology 2020-03-03 Shanshan Jia , Zhaofei Yu , Arno Onken , Yonghong Tian , Tiejun Huang , Jian K. Liu

Nonnegative Matrix Factorization (NMF) is a widely used technique for data representation. Inspired by the expressive power of deep learning, several NMF variants equipped with deep architectures have been proposed. However, these methods…

Machine Learning · Computer Science 2017-11-21 Yuning Qiu , Guoxu Zhou , Kan Xie

Functional connectivity network (FCN) data from functional magnetic resonance imaging (fMRI) is increasingly used for the diagnoses of brain disorders. However, state-of-the-art studies used to build the FCN using a single brain…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Mianxin Liu , Han Zhang , Feng Shi , Dinggang Shen

Nonnegative matrix factorization is a powerful technique to realize dimension reduction and pattern recognition through single-layer data representation learning. Deep learning, however, with its carefully designed hierarchical structure,…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Zhenxing Guo , Shihua Zhang

In recent years, Deep Neural Networks (DNN) based methods have achieved remarkable performance in a wide range of tasks and have been among the most powerful and widely used techniques in computer vision. However, DNN-based methods are both…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Peisong Wang , Jian Cheng

Most functional magnetic resonance imaging studies rely on estimates of hierarchically organized functional brain networks whose segregation and integration reflect the cognitive and behavioral changes in humans. However, most existing…

Neurons and Cognition · Quantitative Biology 2026-04-17 Lingbin Bian , Nizhuan Wang , Leonardo Novelli , Jonathan Keith , Adeel Razi

Nonnegative matrix factorization (NMF) has found many applications including topic modeling and document analysis. Hierarchical NMF (HNMF) variants are able to learn topics at various levels of granularity and illustrate their hierarchical…

Machine Learning · Computer Science 2022-02-16 Joshua Vendrow , Jamie Haddock , Deanna Needell

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Dynamic functional connectivity analysis provides valuable information for understanding brain functional activity underlying different cognitive processes. Besides sliding window based approaches, a variety of methods have been developed…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Yong Fan

Nonnegative matrix factorization (NMF) has become a workhorse for signal and data analytics, triggered by its model parsimony and interpretability. Perhaps a bit surprisingly, the understanding to its model identifiability---the major…

Signal Processing · Electrical Eng. & Systems 2019-03-27 Xiao Fu , Kejun Huang , Nicholas D. Sidiropoulos , Wing-Kin Ma

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

This paper presents a deep neural-network-based hierarchical graphical model for individual and group activity recognition in surveillance scenes. Deep networks are used to recognize the actions of individual people in a scene. Next, a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-16 Zhiwei Deng , Mengyao Zhai , Lei Chen , Yuhao Liu , Srikanth Muralidharan , Mehrsan Javan Roshtkhari , Greg Mori