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The cerebral cortex performs higher-order brain functions and is thus implicated in a range of cognitive disorders. Current analysis of cortical variation is typically performed by fitting surface mesh models to inner and outer cortical…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Samuel Budd , Prachi Patkee , Ana Baburamani , Mary Rutherford , Emma C. Robinson , Bernhard Kainz

We present cortical surface parcellation using spherical deep convolutional neural networks. Traditional multi-atlas cortical surface parcellation requires inter-subject surface registration using geometric features with high processing…

Whole-brain surface extraction is an essential topic in medical imaging systems as it provides neurosurgeons with a broader view of surgical planning and abnormality detection. To solve the problem confronted in current deep learning skull…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Heng Fang , Xi Yang , Taichi Kin , Takeo Igarashi

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Brain age prediction serves as a powerful framework for assessing brain status and detecting deviations associated with neurodevelopmental and neurodegenerative disorders. However, most existing approaches emphasize whole-brain age…

Neurons and Cognition · Quantitative Biology 2026-02-10 Rongzhao He , Dalin Zhu , Ying Wang , Songhong Yue , Leilei Zhao , Yu Fu , Dan Wu , Bin Hu , Weihao Zheng

The development of automated tools for brain morphometric analysis in infants has lagged significantly behind analogous tools for adults. This gap reflects the greater challenges in this domain due to: 1) a smaller-scaled region of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Lilla Zöllei , Juan Eugenio Iglesias , Yangming Ou , P. Ellen Grant , Bruce Fischl

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

Algebraic Topology · Mathematics 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

In this paper, we review widely used statistical analysis frameworks for data defined along cortical and subcortical surfaces that have been developed in last two decades. The cerebral cortex has the topology of a 2D highly convoluted…

Neurons and Cognition · Quantitative Biology 2022-03-15 Moo K. Chung , Jamie L. Hanson , Seth D. Pollak

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

The fetal cortical plate (CP) undergoes drastic morphological changes during the in utero development. Therefore, CP growth and folding patterns are key indicator in the assessment of the brain development and maturation. Magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Priscille de Dumast , Hamza Kebiri , Vincent Dunet , Mériam Koob , Meritxell Bach Cuadra

Neuro-oncological surgery is the primary brain cancer treatment, yet it faces challenges with gliomas due to their invasiveness and the need to preserve neurological function. Hence, radical resection is often unfeasible, highlighting the…

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

Human brain connectome studies aim at extracting and analyzing relevant features associated to pathologies of interest. Usually this consists in modeling the brain connectome as a graph and in using graph metrics as features. A fine brain…

Neurons and Cognition · Quantitative Biology 2020-05-04 Félix Renard , Christian Heinrich , Marine Bouthillon , Maleka Schenck , Francis Schneider , Stéphane Kremer , Sophie Achard

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Classification and quantitative characterization of neuronal morphologies from histological neuronal reconstruction is challenging since it is still unclear how to delineate a neuronal cell class and which are the best features to define…

Neurons and Cognition · Quantitative Biology 2025-03-05 Xavier Vasques , Laurent Vanel , Guillaume Villette , Laura Cif

Brain aging is a widely studied longitudinal process throughout which the brain undergoes considerable morphological changes and various machine learning approaches have been proposed to analyze it. Within this context, brain age prediction…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Matthias Wilms , Jordan J. Bannister , Pauline Mouches , M. Ethan MacDonald , Deepthi Rajashekar , Sönke Langner , Nils D. Forkert

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Skull-stripping separates the skull region of the head from the soft brain tissues. In many cases of brain image analysis, this is an essential preprocessing step in order to improve the final result. This is true for both registration and…

Computer Vision and Pattern Recognition · Computer Science 2012-04-03 Stefan Bauer , Lutz-P. Nolte , Mauricio Reyes