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Lung cancer remains one of the most common and deadliest forms of cancer worldwide. The likelihood of successful treatment depends strongly on the stage at which the disease is diagnosed. Therefore, early detection of lung cancer represents…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Volodymyr Sydorskyi

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

Classification models that provide human-interpretable explanations enhance clinicians' trust and usability in medical image diagnosis. One research focus is the integration and prediction of pathology-related visual attributes used by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Luisa Gallée , Catharina Silvia Lisson , Christoph Gerhard Lisson , Daniela Drees , Felix Weig , Daniel Vogele , Meinrad Beer , Michael Götz

Automated detection and segmentation of pulmonary nodules on lung computed tomography (CT) scans can facilitate early lung cancer diagnosis. Existing supervised approaches for automated nodule segmentation on CT scans require voxel-based…

Computer Vision and Pattern Recognition · Computer Science 2018-02-26 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

Lung cancer is the most common form of cancer found worldwide with a high mortality rate. Early detection of pulmonary nodules by screening with a low-dose computed tomography (CT) scan is crucial for its effective clinical management.…

Image and Video Processing · Electrical Eng. & Systems 2020-06-17 Rakshith Sathish , Rachana Sathish , Ramanathan Sethuraman , Debdoot Sheet

Sensitivity analysis is an effective tool for systematically identifying specific perturbations in parameters that have significant effects on the behavior of a given biosystem, at the scale investigated. In this work, using a…

Quantitative Methods · Quantitative Biology 2007-12-04 Zhihui Wang , Christina M. Birch , Thomas S. Deisboeck

Background and Objective:Computer-aided diagnosis (CAD) systems promote diagnosis effectiveness and alleviate pressure of radiologists. A CAD system for lung cancer diagnosis includes nodule candidate detection and nodule malignancy…

Image and Video Processing · Electrical Eng. & Systems 2022-01-17 Shaohua Zheng , Zhiqiang Shen , Chenhao Peia , Wangbin Ding , Haojin Lin , Jiepeng Zheng , Lin Pan , Bin Zheng , Liqin Huang

Risk stratification of lung nodules is a task of primary importance in lung cancer diagnosis. Any improvement in robust and accurate nodule characterization can assist in identifying cancer stage, prognosis, and improving treatment…

Computer Vision and Pattern Recognition · Computer Science 2017-10-27 Sarfaraz Hussein , Kunlin Cao , Qi Song , Ulas Bagci

Lung cancer is an extremely lethal disease primarily due to its late-stage diagnosis and significant mortality rate, making it the major cause of cancer-related demises globally. Machine Learning (ML) and Convolution Neural network (CNN)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Asha V , Bhavanishankar K

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Kushal Mehta , Arshita Jain , Jayalakshmi Mangalagiri , Sumeet Menon , Phuong Nguyen , David R. Chapman

Lung cancer is one of the most deadly diseases in the world. Detecting such tumors at an early stage can be a tedious task. Existing deep learning architecture for lung nodule identification used complex architecture with large number of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Shah B. Shrey , Lukman Hakim , Muthusubash Kavitha , Hae Won Kim , Takio Kurita

This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

Dense annotations, such as segmentation masks, are expensive and time-consuming to obtain, especially for 3D medical images where expert voxel-wise labeling is required. Weakly supervised approaches aim to address this limitation, but often…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Richard Petersen , Fredrik Kahl , Jennifer Alvén

Purpose To develop and demonstrate a novel tumor shell feature for predicting distant failure in non-small cell lung cancer (NSCLC) and cervical cancer (CC) patients. Patients and Methods The shell predictive model was constructed using…

The importance of radiomics features for predicting patient outcome is now well-established. Early study of prognostic features can lead to a more efficient treatment personalisation. For this reason new radiomics features obtained through…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Paul Desbordes , Diksha , Benoit Macq

Lung cancer accounts for the highest number of cancer deaths globally. Early diagnosis of lung nodules is very important to reduce the mortality rate of patients by improving the diagnosis and treatment of lung cancer. This work proposes an…

Computer Vision and Pattern Recognition · Computer Science 2016-05-27 Tizita Nesibu Shewaye , Alhayat Ali Mekonnen