Related papers: Predicting Extubation Readiness in Extreme Preterm…
After birth, extremely preterm infants often require specialized respiratory management in the form of invasive mechanical ventilation (IMV). Protracted IMV is associated with detrimental outcomes and morbidities. Premature extubation, on…
Extremely preterm infants often require endotracheal intubation and mechanical ventilation during the first days of life. Due to the detrimental effects of prolonged invasive mechanical ventilation (IMV), clinicians aim to extubate infants…
Predicting extubation failure in intensive care is challenging due to complex data and the severe consequences of inaccurate predictions. Machine learning shows promise in improving clinical decision-making but often fails to account for…
Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to…
The complexity of mathematical models describing respiratory mechanics has grown in recent years, however, parameter identifiability of such models has only been studied in the last decade in the context of observable data. This study…
The complexity of mathematical models describing respiratory mechanics has grown in recent years to integrate with cardiovascular models and incorporate nonlinear dynamics. However, additional model complexity has rarely been studied in the…
Most pregnancies and births result in a good outcome, but complications are not uncommon and when they do occur, they can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve…
Preterm births occur at an alarming rate of 10-15%. Preemies have a higher risk of infant mortality, developmental retardation and long-term disabilities. Predicting preterm birth is difficult, even for the most experienced clinicians. The…
Although most pregnancies result in a good outcome, complications are not uncommon and can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve outcomes through better…
Around 5-10\% of newborns need assistance to start breathing. Currently, there is a lack of evidence-based research, objective data collection, and opportunities for learning from real newborn resuscitation emergency events. Generating and…
Infants born before 37 weeks of pregnancy are considered to be preterm. Typically, preterm infants have to be strictly monitored since they are highly susceptible to health problems like hypoxemia (low blood oxygen level), apnea,…
We describe an application of machine learning to the problem of predicting preterm birth. We conduct a secondary analysis on a clinical trial dataset collected by the National In- stitute of Child Health and Human Development (NICHD) while…
The development of respiratory failure is common among patients in intensive care units (ICU). Large data quantities from ICU patient monitoring systems make timely and comprehensive analysis by clinicians difficult but are ideal for…
Respiratory failure is the one of major causes of death in critical care unit. During the outbreak of COVID-19, critical care units experienced an extreme shortage of mechanical ventilation because of respiratory failure related syndromes.…
Nowadays, there is evidence that several factors may increase the risk, for an infant, to require stabilisation or resuscitation manoeuvres at birth. However, this risk factors are not completely known, and a universally applicable model…
We explore the use of traditional and contemporary hidden Markov models (HMMs) for sequential physiological data analysis and sepsis prediction in preterm infants. We investigate the use of classical Gaussian mixture model based HMM, and a…
Apnea-bradycardia is one of the major clinical early indicators of late-onset sepsis occurring in approximately 7% to 10% of all neonates and in more than 25% of very low birth weight infants in NICU. The objective of this paper was to…
Neonatal respiratory distress is a common condition that if left untreated, can lead to short- and long-term complications. This paper investigates the usage of digital stethoscope recorded chest sounds taken within 1min post-delivery, to…
Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…
Recurrent exacerbations remain a common yet preventable outcome for many children with asthma. Machine learning (ML) algorithms using electronic medical records (EMR) could allow accurate identification of children at risk for exacerbations…