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Imaging the structure and observing the dynamics of isolated proteins using single-particle X-ray diffractive imaging (SPI) is one of the potential applications of X-ray free-electron lasers (XFELs). Currently, SPI experiments on isolated…

Single Particle Imaging techniques at X-ray lasers have made significant strides, yet the challenge of determining the orientation of freely rotating molecules during delivery remains. In this study, we propose a novel method to partially…

Chemical Physics · Physics 2025-10-27 Tomas André , Emiliano De Santis , Nicusor Timneanu , Carl Caleman

Video frame interpolation (VFI) enables many important applications that might involve the temporal domain, such as slow motion playback, or the spatial domain, such as stop motion sequences. We are focusing on the former task, where one of…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Uğur Çoğalan , Mojtaba Bemana , Hans-Peter Seidel , Karol Myszkowski

Complex field imaging, which captures both the amplitude and phase information of input optical fields or objects, can offer rich structural insights into samples, such as their absorption and refractive index distributions. However,…

Optics · Physics 2024-05-30 Jingxi Li , Yuhang Li , Tianyi Gan , Che-Yung Shen , Mona Jarrahi , Aydogan Ozcan

We introduce a imaging modality that works by transiently masking image-subregions during a single exposure of a CCD frame. By offsetting subregion exposure time, temporal information is embedded within each stored frame, allowing…

Quantitative Methods · Quantitative Biology 2016-09-08 Gil Bub , Matthias Tecza , Michiel Helmes , Peter Lee , Peter Kohl

The structure and dynamics of isolated nanosamples in free flight can be directly visualized via single-shot coherent diffractive imaging using the intense and short pulses of X-ray free-electron lasers. Wide-angle scattering images even…

Coherent diffractive imaging (CDI) provides new opportunities for high resolution X-ray imaging with simultaneous amplitude and phase contrast. Extensions to CDI broaden the scope of the technique for use in a wide variety of experimental…

Optics · Physics 2016-01-20 Matthew H. Seaberg , Alexandre d'Aspremont , Joshua J. Turner

3D image reconstruction from a set of X-ray projections is an important image reconstruction problem, with applications in medical imaging, industrial inspection and airport security. The innovation of X-ray emitter arrays allows for a…

Medical Physics · Physics 2016-11-23 Maria Klodt , Raphael Hauser

This paper discusses the potential for enhancing the LCLS hard X-ray FEL capabilities. In the hard X-ray regime, a high longitudinal coherence will be the key to such performance upgrade. The method considered here to obtain high…

Accelerator Physics · Physics 2010-08-19 Gianluca Geloni , Vitali Kocharyan , Evgeni Saldin

Optical imaging of the intensity, phase and polarization distributions of optical field is fundamental to numerous applications. Traditional methods rely on bulky optical components and require multiple measurements. Recently,…

Optics · Physics 2024-08-19 Yanjun Bao , Baojun Li

In astronomy there are basically four kinds of observations to extract the information carried by electromagnetic radiation: photometry, imaging, spectroscopy and polarimetry. By optimal exploitation of the first three techniques, X-ray…

Imaging with undetected photons relies upon nonlinear interferometry to extract the spatial image from an infrared probe beam and reveal it in the interference pattern of an easier-to-detect visible beam. Typically, the transmission and…

Coherent diffraction imaging (CDI) of single molecules at atomic resolution is a major goal for the x-ray free electron lasers (XFELs). However, during an imaging pulse, the fast laser-induced ionization may strongly affect the recorded…

Mesoscale and Nanoscale Physics · Physics 2015-06-05 Zoltan Jurek , Robert Thiele , Beata Ziaja , Robin Santra

In support of art investigation, we propose a new source sepa- ration method that unmixes a single X-ray scan acquired from double-sided paintings. Unlike prior source separation meth- ods, which are based on statistical or structural…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Nikos Deligiannis , João F. C. Mota , Bruno Cornelis , Miguel R. D. Rodrigues , Ingrid Daubechies

Hybrid X-ray and magnetic resonance (MR) imaging promises large potential in interventional medical imaging applications due to the broad variety of contrast of MRI combined with fast imaging of X-ray-based modalities. To fully utilize the…

Image and Video Processing · Electrical Eng. & Systems 2019-11-20 Bernhard Stimpel , Christopher Syben , Tobias Würfl , Katharina Breininger , Philipp Hoelter , Arnd Dörfler , Andreas Maier

High-intensity ultrashort X-ray free-electron laser (XFEL) pulses are revolutionizing the study of fundamental nonlinear x-ray matter interactions and coupled electronic and nuclear dynamics. To fully exploit the potential of this powerful…

We describe a method aiming at increasing the dynamic range of X-ray detectors. Two X-ray exposures of an object are acquired at different dose levels and constitute the only input data. The values of the parameters which are needed to…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

X-ray free-electron lasers (XFELs) may allow to employ the single particle imaging (SPI) method to determine the structure of macromolecules that do not form stable crystals. Ultrashort pulses of 10 fs and less allow to outrun complete…

Biological Physics · Physics 2015-11-20 O. Yu. Gorobtsov , U. Lorenz , N. M. Kabachnik , I. A. Vartanyants