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Standardized, validated questionnaires are vital tools in research and healthcare, offering dependable self-report data. Prior work has revealed that virtual agent-administered questionnaires are almost equivalent to self-administered ones…

Human-Computer Interaction · Computer Science 2024-07-09 Hye Sun Yun , Mehdi Arjmand , Phillip Sherlock , Michael K. Paasche-Orlow , James W. Griffith , Timothy Bickmore

An increasingly important goal of psychiatry is the use of brain imaging data to develop predictive models. Here we present two contributions to statistical methodology for this purpose. First, we propose and compare a set of wavelet-domain…

Applications · Statistics 2015-09-17 Philip T. Reiss , Lan Huo , Yihong Zhao , Clare Kelly , R. Todd Ogden

Functional MRI (fMRI) is widely used to examine brain functionality by detecting alteration in oxygenated blood flow that arises with brain activity. This work aims to investigate the neurological variation of human brain responses during…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Naveen Kanigiri , Manohar Suggula , Debanjali Bhattacharya , Neelam Sinha

Background: During an experimental session, behavioral performance fluctuates, yet most neuroimaging analyses of functional connectivity derive a single connectivity pattern. These conventional connectivity approaches assume that since the…

Neurons and Cognition · Quantitative Biology 2017-10-11 Antony D. Passaro , Jean M. Vettel , Jonathan McDaniel , Vernon Lawhern , Piotr J. Franaszczuk , Stephen M. Gordon

Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

Neurons and Cognition · Quantitative Biology 2025-07-14 Sungwoo Ahn , Evie A. Malaia , Leonid L Rubchinsky

Advances in neural recording present increasing opportunities to study neural activity in unprecedented detail. Latent variable models (LVMs) are promising tools for analyzing this rich activity across diverse neural systems and behaviors,…

The quality of generalized linear models (GLMs), frequently used by insurance companies, depends on the choice of interacting variables. The search for interactions is time-consuming, especially for data sets with a large number of…

Machine Learning · Statistics 2025-05-21 Yevhen Havrylenko , Julia Heger

Despite the success of Large Vision--Language Models (LVLMs), most existing architectures suffer from a representation bottleneck: they rely on static, instruction-agnostic vision encoders whose visual representations are utilized in an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Hanpeng Liu , Yaqian Li , Zidan Wang , Shuoxi Zhang , Zihao Bo , Rinyoichi Takezoe , Kaiwen Long , Kun He

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

Methodology · Statistics 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is increasingly utilized for the investigation of the brain's physiological and…

Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities across a wide range of vision-language tasks. However, their performance as embodied agents, which requires multi-round dialogue spatial reasoning and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Xunyi Zhao , Gengze Zhou , Qi Wu

Dynamic Causal Modelling (DCM) is the predominant method for inferring effective connectivity from neuroimaging data. In the 15 years since its introduction, the neural models and statistical routines in DCM have developed in parallel,…

Quantitative Methods · Quantitative Biology 2019-07-15 Peter Zeidman , Amirhossein Jafarian , Nadège Corbin , Mohamed L. Seghier , Adeel Razi , Cathy J. Price , Karl J. Friston

Recent years have seen a resurgence in interest in marketing mix models (MMMs), which are aggregate-level models of marketing effectiveness. Often these models incorporate nonlinear effects, and either implicitly or explicitly assume that…

Econometrics · Economics 2024-08-15 Ryan Dew , Nicolas Padilla , Anya Shchetkina

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

Neurons and Cognition · Quantitative Biology 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Vision-Language Models (VLMs) have demonstrated remarkable progress in multimodal tasks, but remain susceptible to hallucinations, where generated text deviates from the underlying visual content. Existing hallucination detection methods…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Feiran Zhang , Yixin Wu , Zhenghua Wang , Xiaohua Wang , Changze Lv , Xuanjing Huang , Xiaoqing Zheng

This work introduces SteerVLM, a lightweight steering module designed to guide Vision-Language Models (VLMs) towards outputs that better adhere to desired instructions. Our approach learns from the latent embeddings of paired prompts…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Anushka Sivakumar , Andrew Zhang , Zaber Hakim , Chris Thomas

We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of…

Neurons and Cognition · Quantitative Biology 2020-06-03 Yunlong Nie , Eugene Opoku , Laila Yasmin , Yin Song , Jie Wang , Sidi Wu , Vanessa Scarapicchia , Jodie Gawryluk , Liangliang Wang , Jiguo Cao , Farouk S. Nathoo

Brain network analysis is vital for understanding the neural interactions regarding brain structures and functions, and identifying potential biomarkers for clinical phenotypes. However, widely used brain signals such as Blood Oxygen Level…

Machine Learning · Computer Science 2024-05-02 Kaiqiao Han , Yi Yang , Zijie Huang , Xuan Kan , Yang Yang , Ying Guo , Lifang He , Liang Zhan , Yizhou Sun , Wei Wang , Carl Yang

Cardiac disease evaluation depends on multiple diagnostic modalities: electrocardiogram (ECG) to diagnose abnormal heart rhythms, and imaging modalities such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and echocardiography…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Evariste Njomgue Fotso , Buntheng Ly , Hubert Cochet , Maxime Sermesant

Foundation models show strong potential for large-scale, high-dimensional biomedical applications, yet their ability to capture relevant neurobiological characteristics remains underexplored. We systematically evaluate embeddings from two…

Signal Processing · Electrical Eng. & Systems 2026-04-17 Ye Tao , Bradley T. Baker , Yu Wu , Anand D. Sarwate , Sandeep Panta , Sergey Plis , Vince D. Calhoun