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The general linear model (GLM) is a widely popular and convenient tool for estimating the functional brain response and identifying areas of significant activation during a task or stimulus. However, the classical GLM is based on a massive…
Protein Language Models (PLMs) have emerged as performant and scalable tools for predicting the functional impact and clinical significance of protein-coding variants, but they still lag experimental accuracy. Here, we present a novel…
Large Language Models (LLMs) are important tools for reasoning and problem-solving, while they often operate passively, answering questions without actively discovering new ones. This limitation reduces their ability to simulate human-like…
In this paper, we build a general modelling framework for memristors, suitable for the simulation of event-based systems such as hardware spiking neural networks, and more generally, neuromorphic computing systems composed of three…
Mediation analysis has become an important tool in the behavioral sciences for investigating the role of intermediate variables that lie in the path between a randomized treatment and an outcome variable. The influence of the intermediate…
With the advent of Vision-Language Models (VLMs), medical artificial intelligence (AI) has experienced significant technological progress and paradigm shifts. This survey provides an extensive review of recent advancements in Medical…
Brain network discovery aims to find nodes and edges from the spatio-temporal signals obtained by neuroimaging data, such as fMRI scans of human brains. Existing methods tend to derive representative or average brain networks, assuming…
Characterizing the relationship between neural population activity and behavioral data is a central goal of neuroscience. While latent variable models (LVMs) are successful in describing high-dimensional time-series data, they are typically…
Despite the common usage of a canonical, data-independent, hemodynamic response function (HRF), it is known that the shape of the HRF varies across brain regions and subjects. This suggests that a data-driven estimation of this function…
Power and sample size calculations for Wald tests in generalized linear models (GLMs) are often limited to specific cases like logistic regression. More general methods typically require detailed study parameters that are difficult to…
Decision diagrams (DDs) have emerged as an efficient tool for simulating quantum circuits due to their capacity to exploit data redundancies in quantum states and quantum operations, enabling the efficient computation of probability…
The application of deep learning (DL) models to neuroimaging data poses several challenges, due to the high dimensionality, low sample size and complex temporo-spatial dependency structure of these datasets. Even further, DL models act as…
Functional MRI (fMRI) has become the most common method for investigating the human brain. However, fMRI data present some complications for statistical analysis and modeling. One recently developed approach to these data focuses on…
Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…
With the increasing attention to pre-trained vision-language models (VLMs), \eg, CLIP, substantial efforts have been devoted to many downstream tasks, especially in test-time adaptation (TTA). However, previous works focus on learning…
Graph Neural Networks (GNNs) have been widely used in diverse brain network analysis tasks based on preprocessed functional magnetic resonance imaging (fMRI) data. However, their performances are constrained due to high feature sparsity and…
Functional MRI measuring BOLD signal is an increasingly important imaging modality in studying brain functions and neurological disorders. It can be acquired in either a resting-state or a task-based paradigm. Compared to resting-state…
General linear models (GLM) are often constructed and used in statistical inference at the voxel level in brain imaging. In this paper, we explore the basics of random fields and the multiple comparisons on the random fields, which are…
The technology of functional Magnetic Resonance Imaging (fMRI) based on Blood Oxygen Level Dependent (BOLD) signal has been widely used in clinical treatments and brain function researches. The BOLD signal has to be preprocessed before…
Functional Magnetic Resonance Imaging (fMRI) is an advanced neuroimaging method that enables in-depth analysis of brain activity by measuring dynamic changes in the blood oxygenation level-dependent (BOLD) signals. However, the…