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We study overdamped stochastic dynamics confined by hard reflecting boundaries and show that the combination of boundary geometry and an anisotropic diffusion tensor generically generates directed motion. At the level of individual…

Statistical Mechanics · Physics 2026-01-14 Meitar Goldfarb , Stanislav Burov

Computational modeling and simulation of fluid-structure interactions constitute a fundamental cornerstone for advancing aerospace engineering endeavors. This paper addresses the notion and implementation of the immersed boundary method for…

Computational Physics · Physics 2025-12-24 Longqing Ge , Qingdong Cai , Yonghao Zhang , Tianbai Xiao

Neural systems face the challenge of maintaining reliable representations amid variations from plasticity and spontaneous activity. In particular, the spontaneous dynamics in neuronal circuit is known to operate near a highly variable…

Neurons and Cognition · Quantitative Biology 2026-03-24 Zhuda Yang , Junhao Liang , Wing Ho Yung , Changsong Zhou

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak

A fundamental aspect of learning in biological neural networks is the plasticity property which allows them to modify their configurations during their lifetime. Hebbian learning is a biologically plausible mechanism for modeling the…

Neural and Evolutionary Computing · Computer Science 2021-03-16 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , Matt Coler , George Fletcher , Mykola Pechenizkiy

It has been proposed that adaptation in complex systems is optimized at the critical boundary between ordered and disordered dynamical regimes. Here, we review models of evolving dynamical networks that lead to self-organization of network…

Adaptation and Self-Organizing Systems · Physics 2008-11-07 Thimo Rohlf , Stefan Bornholdt

This paper proposes a solution to the problem of smooth path planning for mobile robots in dynamic and unknown environments. A novel concept of Time-Warped Grid is introduced to predict the pose of obstacles in the environment and avoid…

Robotics · Computer Science 2019-03-19 Siavash Farzan , Guilherme N. DeSouza

Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and the cell nucleus. However, it remains poorly understood how…

The proposed stochastic model for pedestrian dynamics is based on existing approaches using cellular automata, combined with substantial extensions, to compensate the deficiencies resulting of the discrete grid structure. This agent motion…

Physics and Society · Physics 2021-04-01 Michael Schultz

Dynamical criticality has been shown to enhance information processing in dynamical systems, and there is evidence for self-organized criticality in neural networks. A plausible mechanism for such self-organization is activity dependent…

Adaptation and Self-Organizing Systems · Physics 2012-09-18 Felix Droste , Anne-Ly Do , Thilo Gross

The state space of a conventional Hopfield network typically exhibits many different attractors of which only a small subset satisfy constraints between neurons in a globally optimal fashion. It has recently been demonstrated that combining…

Adaptation and Self-Organizing Systems · Physics 2014-09-02 Alexander Woodward , Tom Froese , Takashi Ikegami

Representing and reasoning about physical space is fundamental to animal survival, and the mammalian lineage expresses a wealth of specialized neural representations that encode space. Grid cells, whose discovery earned a Nobel prize, are a…

Neurons and Cognition · Quantitative Biology 2023-11-29 Rylan Schaeffer , Mikail Khona , Adrian Bertagnoli , Sanmi Koyejo , Ila Rani Fiete

Humans and other organisms make decisions choosing between different options, with the aim to maximize the reward and minimize the cost. The main theoretical framework for modeling the decision-making process has been based on the highly…

Neurons and Cognition · Quantitative Biology 2024-11-19 Olga Tapinova , Tal Finkelman , Tamar Reitich-Stolero , Rony Paz , Assaf Tal , Nir S. Gov

When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

In the absence of environmental cues, a migrating cell performs an isotropic random motion. Recently, the breaking of this isotropy has been observed when cells move in the presence of asymmetric adhesive patterns. However, up to now the…

Soft Condensed Matter · Physics 2015-06-17 M. Le Berre , Yan-Jun Liu , J. Hu , P. Maiuri , O. Bénichou , R. Voituriez , Y. Chen , M. Piel

Flexible cognition requires the ability to rapidly detect systematic functions of variables and guide future behavior based on predictions. The model described here proposes a potential framework for patterns of neural activity to detect…

Neurons and Cognition · Quantitative Biology 2018-10-17 Michael E. Hasselmo

A sufficiently large information flux in recurrent neural networks, quantified by the mutual information between successive network states, is considered a prerequisite for rich information processing capabilities. This raises the question…

Neurons and Cognition · Quantitative Biology 2026-05-15 Claus Metzner , Ali Ghebleh , Karin Prebeck , Achim Schilling , Andreas Maier , Thomas Kinfe , Patrick Krauss

Like ants, some microorganisms are known to leave trails on surfaces to communicate. We explore how trail-mediated self-interaction could affect the behavior of individual microorganisms when diffusive spreading of the trail is negligible…

Biological Physics · Physics 2016-07-15 W. Till Kranz , Anatolij Gelimson , Kun Zhao , Gerard C. L. Wong , Ramin Golestanian

Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain's neural networks. A central question is how synapses, with access to only local information about the network, can still organize collectively and…

Neural and Evolutionary Computing · Computer Science 2019-12-06 Dina Obeid , Hugo Ramambason , Cengiz Pehlevan

We develop methods for investigating protein drift-diffusion dynamics in heterogeneous cell membranes and the roles played by geometry, diffusion, chemical kinetics, and phase separation. Our hybrid stochastic numerical methods combine…

Biological Physics · Physics 2023-02-28 Patrick D. Tran , Thomas A. Blanpied , Paul J. Atzberger