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Over the recent years, Graph Neural Networks have become increasingly popular in network analytic and beyond. With that, their architecture noticeable diverges from the classical multi-layered hierarchical organization of the traditional…

Machine Learning · Computer Science 2021-05-17 Stanislav Sobolevsky

Stacking is a widely used model averaging technique that asymptotically yields optimal predictions among linear averages. We show that stacking is most effective when model predictive performance is heterogeneous in inputs, and we can…

Methodology · Statistics 2021-10-29 Yuling Yao , Gregor Pirš , Aki Vehtari , Andrew Gelman

The human body is a complex organism whose gross mechanical properties are enabled by an interconnected musculoskeletal network controlled by the nervous system. The nature of musculoskeletal interconnection facilitates stability, voluntary…

Tissues and Organs · Quantitative Biology 2016-12-20 Andrew C. Murphy , Sarah F. Muldoon , David Baker , Adam Lastowka , Brittany Bennett , Muzhi Yang , Danielle S. Bassett

Geometric and structural constraints greatly restrict the selection of folds adapted by protein backbones, and yet, folded proteins show an astounding diversity in functionality. For structure to have any bearing on function, it is thus…

Biological Physics · Physics 2010-04-20 Brinda K. V. , Saraswathi Vishveshwara , Smitha Vishveshwara

Network motifs are characteristic patterns which occur in the networks essentially more frequently than the other patterns. For five motifs found in S. Itzkovitz, U. Alon, Phys. Rev.~E, 2005, 71, 026117-1, hierarchical random graphs are…

Mathematical Physics · Physics 2015-04-02 Monika Kotorowicz , Yuri Kozitsky

Matrix stiffness expressions are derived for the particle movements in an assembly of rigid granules having compliant contacts. The derivations include stiffness terms that arise from the particle shapes at their contacts. These geometric…

Soft Condensed Matter · Physics 2019-01-23 Matthew R. Kuhn , Ching S. Chang

Variable selection for models including interactions between explanatory variables often needs to obey certain hierarchical constraints. The weak or strong structural hierarchy requires that the existence of an interaction term implies at…

Statistics Theory · Mathematics 2016-11-10 Yiyuan She , Zhifeng Wang , He Jiang

Complex network theory aims to model and analyze complex systems that consist of multiple and interdependent components. Among all studies on complex networks, topological structure analysis is of the most fundamental importance, as it…

Social and Information Networks · Computer Science 2010-09-15 Bo Yang , Jiming Liu

Controlling the self-assembly of supramolecular structures is vital for living cells, and a central challenge for engineering at the nano- and microscales. Nevertheless, even particles without optimized shapes can robustly form well-defined…

Soft Condensed Matter · Physics 2018-03-09 Martin Lenz , Thomas A. Witten

Hierarchical clustering seeks to uncover nested structures in data by constructing a tree of clusters, where deeper levels reveal finer-grained relationships. Traditional methods, including linkage approaches, face three major limitations:…

Machine Learning · Computer Science 2025-11-25 Maximilien Dreveton , Matthias Grossglauser , Daichi Kuroda , Patrick Thiran

Designing strong and robust bio-inspired structures requires an understanding of how function arises from the architecture and geometry of materials found in nature. We draw from trabecular bone, a lightweight bone tissue that exhibits a…

Biological Physics · Physics 2019-10-09 Chantal Nguyen , Darin Peetz , Ahmed E. Elbanna , Jean M. Carlson

Materials that behave like machines, e.g. functional materials that are able to change shape in response to external stimuli (Bhattacharya and James, 2005), often do so by exploiting phase transitions. Shape memory materials and the tail…

Materials Science · Physics 2019-03-13 Matthew P. O'Donnell , Jonathan P. Stacey , Isaac V. Chenchiah , Alberto Pirrera

Knowledge silos emerge when structural properties of organizational interaction networks limit the diffusion of information. These structural barriers are known to take many forms at different scales - hubs in otherwise sparse…

Physics and Society · Physics 2022-03-03 Laurent Hébert-Dufresne , Guillaume St-Onge , John Meluso , James Bagrow , Antoine Allard

Anatomical connectivity between different regions in the brain can be mapped to a network representation, the connectome, where the intensities of the links, the weights, influence its structural resilience and the functional processes it…

Neurons and Cognition · Quantitative Biology 2025-04-09 Laia Barjuan , Muhua Zheng , M. Ángeles Serrano

Using each node's degree as a proxy for its importance, the topological hierarchy of a complex network is introduced and quantified. We propose a simple dynamical process used to construct networks which are either maximally or minimally…

Soft Condensed Matter · Physics 2008-06-24 Ala Trusina , Sergei Maslov , Petter Minnhagen , Kim Sneppen

Artificial neural networks used for reinforcement learning are structurally rigid, meaning that each optimized parameter of the network is tied to its specific placement in the network structure. It also means that a network only works with…

Neural and Evolutionary Computing · Computer Science 2024-05-20 Joachim Winther Pedersen , Erwan Plantec , Eleni Nisioti , Milton Montero , Sebastian Risi

In many biological materials with a hierarchical structure there is an intriguing and unique mechanism responsible for the 'propagation' of order from the molecular to the nano- or micro-scale level. Here we present a much simpler molecular…

Context-dependent nature of biological phenomena are well documented in every branch of biology. While there have been few previous attempts to (implicitly) model various facets of biological context-dependence, a formal and general…

Other Quantitative Biology · Quantitative Biology 2011-11-28 Anirban Banerji

A defining property of complex systems is that they have multiscale structure. How does this multiscale structure come about? We argue that within systems there emerges a hierarchy of scales that contribute to a system's causal workings. An…

Information Theory · Computer Science 2025-10-15 Abel Jansma , Erik Hoel

Chirality frustrates and shapes the assembly of flexible filaments in rope-like, twisted bundles and fibers by introducing gradients of both filament shape (i.e. curvature) and packing throughout the structure. Previous models of chiral…

Soft Condensed Matter · Physics 2016-12-08 Douglas M. Hall , Gregory M. Grason