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In genetic studies of complex diseases, the underlying mode of inheritance is often not known. Thus, the most powerful test or other optimal procedure for one model, e.g. recessive, may be quite inefficient if another model, e.g. dominant,…

Statistics Theory · Mathematics 2007-06-13 Gang Zheng , Boris Freidlin , Joseph L. Gastwirth

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

Symbolic regression is a machine learning method with the goal to produce interpretable results. Unlike other machine learning methods such as, e.g. random forests or neural networks, which are opaque, symbolic regression aims to model and…

Machine Learning · Computer Science 2024-06-07 Yousef A. Radwan , Gabriel Kronberger , Stephan Winkler

When a Genetic Algorithm (GA), or a stochastic algorithm in general, is employed in a statistical problem, the obtained result is affected by both variability due to sampling, that refers to the fact that only a sample is observed, and…

Computation · Statistics 2019-03-07 Manuel Rizzo , Francesco Battaglia

Genomic aberrations, such as somatic copy number alterations, are frequently observed in tumor tissue. Recurrent aberrations, occurring in the same region across multiple subjects, are of interest because they may highlight genes associated…

Statistics Theory · Mathematics 2014-03-11 Vonn Walter , Fred A. Wright , Andrew B. Nobel

Genetic Programming, a kind of evolutionary computation and machine learning algorithm, is shown to benefit significantly from the application of vectorized data and the TensorFlow numerical computation library on both CPU and GPU…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-11 Kai Staats , Edward Pantridge , Marco Cavaglia , Iurii Milovanov , Arun Aniyan

The complex effect of genetic algorithm's (GA) operators and parameters to its performance has been studied extensively by researchers in the past but none studied their interactive effects while the GA is under different problem sizes. In…

Neural and Evolutionary Computing · Computer Science 2015-08-04 Jaderick P. Pabico , Elizer A. Albacea

We investigate a family of $(\mu+\lambda)$ Genetic Algorithms (GAs) which creates offspring either from mutation or by recombining two randomly chosen parents. By scaling the crossover probability, we can thus interpolate from a fully…

Neural and Evolutionary Computing · Computer Science 2021-02-16 Furong Ye , Hao Wang , Carola Doerr , Thomas Bäck

Genetic algorithms (GAs) have a long history of over four decades. GAs are adaptive heuristic search algorithms that provide solutions for optimization and search problems. The GA derives expression from the biological terminology of…

Optics · Physics 2018-12-03 Kaspar Höschel , Vasudevan Lakshminarayanan

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

There is an abundance of prior research on the optimization of production systems, but there is a research gap when it comes to optimizing which components should be included in a design, and how they should be connected. To overcome this…

Neural and Evolutionary Computing · Computer Science 2024-02-05 N. Paape , J. A. W. M. van Eekelen , M. A. Reniers

Genetic algorithms are considered as one of the most efficient search techniques. Although they do not offer an optimal solution, their ability to reach a suitable solution in considerably short time gives them their respectable role in…

Neural and Evolutionary Computing · Computer Science 2014-01-22 Ayman M. Bahaa-Eldin , A. M. A. Wahdan , H. M. K. Mahdi

Multi-model inference covers a wide range of modern statistical applications such as variable selection, model confidence set, model averaging and variable importance. The performance of multi-model inference depends on the availability of…

Statistics Theory · Mathematics 2019-06-07 Ching-Wei Cheng , Guang Cheng

We propose and analyse a variant of the recently introduced kinetic based optimization method that incorporates ideas like survival-of-the-fittest and mutation strategies well-known from genetic algorithms. Thus, we provide a first attempt…

Optimization and Control · Mathematics 2024-07-18 Giacomo Albi , Federica Ferrarese , Claudia Totzeck

Deepfakes utilise Artificial Intelligence (AI) techniques to create synthetic media where the likeness of one person is replaced with another. There are growing concerns that deepfakes can be maliciously used to create misleading and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Nyee Thoang Lim , Meng Yi Kuan , Muxin Pu , Mei Kuan Lim , Chun Yong Chong

Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and…

Machine Learning · Computer Science 2019-12-16 Siddhartha Dhar Choudhury , Shashank Pandey , Kunal Mehrotra

Genetic Programming is an evolutionary algorithm that generates computer programs, or mathematical expressions, to solve complex problems. In this Guide, we demonstrate how to use Genetic Programming to develop surrogate models to mitigate…

We recently reported that the simple genetic algorithm (SGA) is capable of performing a remarkable form of sublinear computation which has a straightforward connection with the general problem of interacting attributes in data-mining. In…

Neural and Evolutionary Computing · Computer Science 2009-05-18 Keki M. Burjorjee

Large language models (LLMs) have introduced substantial challenges to software quality assurance due to their generative, probabilistic, and open-ended nature, which intensifies the oracle problem and limits the applicability of…

Software Engineering · Computer Science 2026-05-15 Zheng Zheng , Zenghui Zhou , Yinwang Xu , Daixu Ren , Tsong Yueh Chen

Genetic algorithms are a powerful tool in optimization for single and multi-modal functions. This paper provides an overview of their fundamentals with some analytical examples. In addition, we explore how they can be used as a parameter…