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Software systems continuously evolve due to new functionalities, requirements, or maintenance activities. In the context of software evolution, software refactoring has gained a strategic relevance. The space of possible software…

Software Engineering · Computer Science 2024-01-31 Vittorio Cortellessa , Daniele Di Pompeo , Michele Tucci

The design and the implementation of a genetic algorithm are described. The applicability domain is on structure-activity relationships expressed as multiple linear regressions and predictor variables are from families of structure-based…

Neural and Evolutionary Computing · Computer Science 2009-06-29 Lorentz Jantschi

The genetic algorithm is an optimization procedure motivated by biological evolution and is successfully applied to optimization problems in different areas. A statistical mechanics model for its dynamics is proposed based on the…

Statistical Mechanics · Physics 2009-10-31 Stefan Bornholdt

Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical…

Methodology · Statistics 2016-06-13 Gabriela Bettella Cybis , Marcio Valk , Silvia Regina Costa Lopes

Metamorphic Testing (MT) is a testing technique that can effectively alleviate the oracle problem. MT uses Metamorphic Relations (MRs) to determine if a test case passes or fails. MRs specify how the outputs should vary in response to…

Software Engineering · Computer Science 2023-05-19 Alejandra Duque-Torres , Dietmar Pfahl , Claus Klammer , Stefan Fischer

Metamorphic Testing (MT) addresses the test oracle problem by examining the relationships between input-output pairs in consecutive executions of the System Under Test (SUT). These relations, known as Metamorphic Relations (MRs), specify…

Software Engineering · Computer Science 2023-10-23 Alejandra Duque-Torres , Dietmar Pfahl

The application of genetic algorithms (GAs) to many optimization problems in organizations often results in good performance and high quality solutions. For successful and efficient use of GAs, it is not enough to simply apply simple GAs…

Neural and Evolutionary Computing · Computer Science 2008-12-18 Maroun Bercachi , Philippe Collard , Manuel Clergue , Sébastien Verel

Analyzing large datasets to select optimal features is one of the most important research areas in machine learning and data mining. This feature selection procedure involves dimensionality reduction which is crucial in enhancing the…

Neural and Evolutionary Computing · Computer Science 2024-09-24 Zhila Yaseen Taha , Abdulhady Abas Abdullah , Tarik A. Rashid

Proteins are the workhorses of life and gaining insight on their functions is of paramount importance for applications such as drug design. However, the experimental validation of functions of proteins is highly-resource consuming.…

Software Engineering · Computer Science 2019-04-18 Morteza Pourreza Shahri , Madhusudan Srinivasan , Gillian Reynolds , Diane Bimczok , Indika Kahanda , Upulee Kanewala

Genetic Algorithms (GA) are a class of metaheuristic global optimization methods inspired by the process of natural selection among individuals in a population. Despite their widespread use, a comprehensive theoretical analysis of these…

Optimization and Control · Mathematics 2025-02-24 Giacomo Borghi , Lorenzo Pareschi

Metamorphic testing (MT) alleviates the oracle problem by checking metamorphic relations (MRs) across multiple test executions. The fault detection effectiveness of MT is influenced not only by the choice and quality of MRs, but also by how…

Software Engineering · Computer Science 2025-12-16 Zenghui Zhou , Pak-Lok Poon , Zheng Zheng , Xiao-Yi Zhang

High-dimensional phenotypes hold promise for richer findings in association studies, but testing of several phenotype traits aggravates the grand challenge of association studies, that of multiple testing. Several methods have recently been…

Methodology · Statistics 2013-05-14 Pekka Marttinen , Jussi Gillberg , Aki Havulinna , Jukka Corander , Samuel Kaski

Symbolic regression is the process of identifying mathematical expressions that fit observed output from a black-box process. It is a discrete optimization problem generally believed to be NP-hard. Prior approaches to solving the problem…

Neural and Evolutionary Computing · Computer Science 2021-11-19 T. Nathan Mundhenk , Mikel Landajuela , Ruben Glatt , Claudio P. Santiago , Daniel M. Faissol , Brenden K. Petersen

Many statistical problems involve optimization over a discrete parameter space having an unknown dimension. In such settings, gradient-based methods often fail due to the non-differentiability of the objective function or a non-convex or…

Applications · Statistics 2026-03-19 Mo Li , QiQi Lu , Robert Lund , Xueheng Shi

It is widely recognized nowadays that complex diseases are caused by, amongst the others, multiple genetic factors. The recent advent of genome-wide association study (GWA) has triggered a wave of research aimed at discovering genetic…

Applications · Statistics 2011-09-30 Nguyen Xuan Vinh

Traditionally Genetic Algorithm has been used for optimization of unimodal and multimodal functions. Earlier researchers worked with constant probabilities of GA control operators like crossover, mutation etc. for tuning the optimization in…

Neural and Evolutionary Computing · Computer Science 2021-04-20 Avijit Basak

Genetic programming has been widely used in the engineering field. Compared with the conventional genetic programming and artificial neural network, geometric semantic genetic programming (GSGP) is superior in astringency and computing…

Neural and Evolutionary Computing · Computer Science 2017-12-06 Juncai Xu , Zhenzhong Shen , Qingwen Ren , Xin Xie , Zhengyu Yang

Identifying and selecting high-quality Metamorphic Relations (MRs) is a challenge in Metamorphic Testing (MT). While some techniques for automatically selecting MRs have been proposed, they are either domain-specific or rely on strict…

Software Engineering · Computer Science 2024-01-05 Alejandra Duque-Torres , Dietmar Pfahl , Claus Klammer , Stefan Fischer

Genetic algorithms have been used in recent decades to solve a broad variety of search problems. These algorithms simulate natural selection to explore a parameter space in search of solutions for a broad variety of problems. In this paper,…

Neural and Evolutionary Computing · Computer Science 2022-03-25 Yoshio Martinez , Katya Rodriguez , Carlos Gershenson

This paper concerns applications of genetic algorithms and genetic programming to tasks for which it is difficult to find a representation that does not map to a highly complex and discontinuous fitness landscape. In such cases the standard…

Neural and Evolutionary Computing · Computer Science 2016-05-06 Michal Gregor , Juraj Spalek
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