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Characterizing structural and dynamic properties of proteins and large macromolecular assemblies is crucial to understand the molecular mechanisms underlying biological functions. In the field of Structural Biology, no single method…

Quantitative Methods · Quantitative Biology 2023-10-04 Samuel Hoff , Maximilian Zinke , Nadia Izadi-Pruneyre , Massimiliano Bonomi

While data science has emerged as a contentious new scientific field, enormous debates and discussions have been made on it why we need data science and what makes it as a science. In reviewing hundreds of pieces of literature which include…

Computers and Society · Computer Science 2020-07-01 Longbing Cao

Data science is the business of learning from data, which is traditionally the business of statistics. Data science, however, is often understood as a broader, task-driven and computationally-oriented version of statistics. Both the term…

Other Statistics · Statistics 2018-10-11 Iain Carmichael , J. S. Marron

The twenty-first century has ushered in the age of big data and data economy, in which data DNA, which carries important knowledge, insights and potential, has become an intrinsic constituent of all data-based organisms. An appropriate…

Computers and Society · Computer Science 2020-07-08 Longbing Cao

There has been an increasing recognition of the value of data and of data-based decision making. As a consequence, the development of data science as a field of study has intensified in recent years. However, there is no systematic and…

Other Computer Science · Computer Science 2024-01-05 M. Tamer Özsu

Data science is creating very exciting trends as well as significant controversy. A critical matter for the healthy development of data science in its early stages is to deeply understand the nature of data and data science, and to discuss…

Computers and Society · Computer Science 2020-07-01 Longbing Cao

Although data science builds on knowledge from computer science, mathematics, statistics, and other disciplines, data science is a unique field with many mysteries to unlock: challenging scientific questions and pressing questions of…

Computers and Society · Computer Science 2020-02-14 Jeannette M. Wing

Proteins, by virtue of their central role in most biological processes, represent one of the key subjects of the study of molecular evolution. Inherent to the indispensability of proteins for living cells is the fact that a given protein…

Biomolecules · Quantitative Biology 2007-05-23 Eric J. Deeds , Eugene I. Shakhnovich

Networks effectively capture interactions among components of complex systems, and have thus become a mainstay in many scientific disciplines. Growing evidence, especially from biology, suggest that networks undergo changes over time, and…

Methodology · Statistics 2020-03-10 Ali Shojaie

Causal inference from observational data is the goal of many data analyses in the health and social sciences. However, academic statistics has often frowned upon data analyses with a causal objective. The introduction of the term "data…

Machine Learning · Statistics 2019-04-11 Miguel A. Hernán , John Hsu , Brian Healy

The discipline of `theoretical biology' has been developing from its inception several decades ago almost in parallel with the advances in biology, so much so that the latter is often considered to be almost exclusively an empirical…

Biological Physics · Physics 2025-06-10 Shakti N. Menon , Sitabhra Sinha

We highlight the role of Data Science in Biomedicine. Our manuscript goes from the general to the particular, presenting a global definition of Data Science and showing the trend for this discipline together with the terms of cloud…

Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structural modeling. Protein structural modeling, such as predicting…

Biomolecules · Quantitative Biology 2020-07-17 Wenhao Gao , Sai Pooja Mahajan , Jeremias Sulam , Jeffrey J. Gray

This manuscript provides a systemic and data-centric view of what we term essential data science, as a natural ecosystem with challenges and missions stemming from the fusion of data universe with its multiple combinations of the 5D…

Machine Learning · Computer Science 2026-01-14 Emilio Porcu , Roy El Moukari , Laurent Najman , Francisco Herrera , Horst Simon

This paper introduces Surgical Data Science as an emerging scientific discipline. Key perspectives are based on discussions during an intensive two-day international interactive workshop that brought together leading researchers working in…

Biological engineering, the convergence between engineering and biology, is at the forefront of significant advances in healthcare, agriculture, and environmental sustainability, making it highly relevant to current scientific and societal…

Other Quantitative Biology · Quantitative Biology 2026-02-17 Ulrike A. Nuber , Viktor Stein

Data science has arrived, and computational statistics is its engine. As the scale and complexity of scientific and industrial data grow, the discipline of computational statistics assumes an increasingly central role among the statistical…

Other Statistics · Statistics 2022-04-13 Andrew J. Holbrook , Akihiko Nishimura , Xiang Ji , Marc A. Suchard

Data Science is currently a popular field of science attracting expertise from very diverse backgrounds. Current learning practices need to acknowledge this and adapt to it. This paper summarises some experiences relating to such learning…

General Literature · Computer Science 2018-07-11 Yehia Elkhatib

This paper tries to throw light in the usage of data structures in the field of information retrieval. Information retrieval is an area of study which is gaining momentum as the need and urge for sharing and exploring information is growing…

Information Retrieval · Computer Science 2016-02-26 V. R. Kanagavalli , G. Maheeja

Data science is gaining more and more and widespread attention, but no consensus viewpoint on what data science is has emerged. As a new science, its objects of study and scientific issues should not be covered by established sciences. Data…

Databases · Computer Science 2015-01-22 Yangyong Zhu , Yun Xiong
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