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Migrations have played an important role in shaping the genetic diversity of human populations. Understanding genomic data thus requires careful modeling of historical gene flow. Here we consider the effect of relatively recent population…

Populations and Evolution · Quantitative Biology 2012-04-26 Simon Gravel

Over the last fifty years, geneticists have made great strides in understanding how our species' evolutionary history gave rise to current patterns of human genetic diversity classically summarized by Lewontin in his 1972 paper, 'The…

Populations and Evolution · Quantitative Biology 2022-02-14 Shyamalika Gopalan , Samuel Patillo Smith , Katharine Korunes , Iman Hamid , Sohini Ramachandran , Amy Goldberg

Time-continuous dynamical systems defined on graphs are often used to model complex systems with many interacting components in a non-spatial context. In the reverse sense attaching meaningful dynamics to given 'interaction diagrams' is a…

Molecular Networks · Quantitative Biology 2010-07-02 Markus Kirkilionis , Luca Sbano

Graphs are used to represent and analyze data in domains as diverse as physics, biology, chemistry, planetary science, and the social sciences. Across domains, random graph models relate generative processes to expected graph properties,…

Physics and Society · Physics 2025-09-12 Cole Mathis , Harrison B. Smith

Adaptive networks model social, physical, technical, or biological systems as attributed graphs evolving at the level of both their topology and data. They are naturally described by graph transformation, but the majority of authors take an…

Discrete Mathematics · Computer Science 2021-12-22 Nicolas Behr , Bello Shehu Bello , Sebastian Ehmes , Reiko Heckel

Graph learning methods have recently been receiving increasing interest as means to infer structure in datasets. Most of the recent approaches focus on different relationships between a graph and data sample distributions, mostly in…

Machine Learning · Computer Science 2020-03-23 Hermina Petric Maretic , Pascal Frossard

In a (two-type) Wright-Fisher diffusion with directional selection and two-way mutation, let $x$ denote today's frequency of the beneficial type, and given $x$, let $h(x)$ be the probability that, among all individuals of today's…

Populations and Evolution · Quantitative Biology 2015-07-10 Ute Lenz , Sandra Kluth , Ellen Baake , Anton Wakolbinger

Random graphs are more and more used for modeling real world networks such as evolutionary networks of proteins. For this purpose we look at two different models and analyze how properties like connectedness and degree distributions are…

Probability · Mathematics 2019-02-05 Klemens Taglieber , Uta Freiberg

Population structure can have a significant effect on evolution. For some systems with sufficient symmetry, analytic results can be derived within the mathematical framework of evolutionary graph theory which relate to the outcome of the…

Populations and Evolution · Quantitative Biology 2019-03-11 Christopher E. Overton , Mark Broom , Christoforos Hadjichrysanthou , Kieran J. Sharkey

Wright-Fisher diffusions describe the evolution of the type composition of an infinite haploid population with two types (say type $0$ and type $1$) subject to neutral reproductions, and possibly selection and mutations. In the present…

Probability · Mathematics 2022-12-21 Grégoire Véchambre

We introduce the Graph Mixture Density Networks, a new family of machine learning models that can fit multimodal output distributions conditioned on graphs of arbitrary topology. By combining ideas from mixture models and graph…

Machine Learning · Computer Science 2021-06-28 Federico Errica , Davide Bacciu , Alessio Micheli

Continuous mixtures of distributions are widely employed in the statistical literature as models for phenomena with highly divergent outcomes; in particular, many familiar heavy-tailed distributions arise naturally as mixtures of…

Methodology · Statistics 2017-10-10 Carter T. Butts

We propose generalizations of a number of standard network models, including the classic random graph, the configuration model, and the stochastic block model, to the case of time-varying networks. We assume that the presence and absence of…

Social and Information Networks · Computer Science 2018-05-02 Xiao Zhang , Cristopher Moore , M. E. J. Newman

Gene interaction graphs aim to capture various relationships between genes and can represent decades of biology research. When trying to make predictions from genomic data, those graphs could be used to overcome the curse of dimensionality…

In evolutionary dynamics, well-mixed populations are almost always associated with all-to-all interactions; mathematical models are based on complete graphs. In most cases, these models do not predict fixation probabilities in groups of…

Populations and Evolution · Quantitative Biology 2024-02-28 Francisco Herrerías-Azcué , Vicente Pérez-Muñuzuri , Tobias Galla

Evolution in finite populations is often modelled using the classical Moran process. Over the last ten years this methodology has been extended to structured populations using evolutionary graph theory. An important question in any such…

Populations and Evolution · Quantitative Biology 2015-05-25 Karan Pattni , Mark Broom , Jan Rychtar , Lara J. Silvers

In mathematical phylogenetics, evolutionary relationships are often represented by trees and networks. The latter are typically used whenever the relationships cannot be adequately described by a tree, which happens when so-called…

Populations and Evolution · Quantitative Biology 2025-12-05 Mirko Wilde , Mareike Fischer

Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a challenging task. In this paper, we present a statistical model…

Populations and Evolution · Quantitative Biology 2012-11-20 Joseph K. Pickrell , Jonathan K. Pritchard

Graphs are fundamental data structures which concisely capture the relational structure in many important real-world domains, such as knowledge graphs, physical and social interactions, language, and chemistry. Here we introduce a powerful…

Machine Learning · Computer Science 2018-03-12 Yujia Li , Oriol Vinyals , Chris Dyer , Razvan Pascanu , Peter Battaglia

Mixture models are probabilistic models aimed at uncovering and representing latent subgroups within a population. In the realm of network data analysis, the latent subgroups of nodes are typically identified by their connectivity…

Methodology · Statistics 2020-05-27 Giacomo De Nicola , Benjamin Sischka , Göran Kauermann
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