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We report a novel technique to passively create strong secondary flows at moderate to high flow rates in microchannels, accurately control them and finally, due to their deterministic nature, program them into microfluidic platforms. Based…

Fluid Dynamics · Physics 2011-10-20 Hamed Amini , Mahdokht Masaeli , Dino Di Carlo

Many microfluidic devices use macroscopic pressure differentials to overcome viscous friction and generate flows in microchannels. In this work, we investigate how the chemical and geometric properties of the channel walls can drive a net…

Motile cilia are used by many eukaryotic cells to transport flow. Cilia-driven flows are important to many physiological functions, yet a deep understanding of the interplay between the mechanical structure of cilia and their physiological…

Fluid Dynamics · Physics 2016-04-06 Hanliang Guo , Eva Kanso

We use a 3D computational model to study the fluid transport and mixing due to the beating of an infinite array of cilia. In accord with recent experiments, we observe two distinct regions: a fluid transport region above the cilia and a…

Fluid Dynamics · Physics 2014-03-24 Yang Ding , Janna Nawroth , Margaret McFall-Ngai , Eva Kanso

Micro-scale cilia play a vital role in mucociliary clearance (MCC) in the human respiratory airways. In this numerical study, we examine fluid transport driven by the active beating of a single filament immersed in a three-dimensional…

Fluid Dynamics · Physics 2026-02-02 Qian Mao , Umberto d'Ortona , Julien Favier

Motile cilia beat in an asymmetric fashion in order to propel the surrounding fluid. When many cilia are located on a surface, their beating can synchronise such that their phases form metachronal waves. Here, we computationally study a…

Soft Condensed Matter · Physics 2023-09-29 David J. Hickey , Ramin Golestanian , Andrej Vilfan

We propose to drive open microfluidic systems by shear in a covering fluid layer, e.g., oil covering water-filled chemical channels. The advantages as compared to other means of pumping are simpler forcing and prevention of evaporation of…

Soft Condensed Matter · Physics 2009-11-11 Markus Rauscher , S. Dietrich , Joel Koplik

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

Soft Condensed Matter · Physics 2016-04-20 Nicolas Bruot , Pietro Cicuta

Particle-like chiral magnetic skyrmions can flow in nanotracks and behave like chiral fluids. Using interacting flows to perform logical operations is an important topic in microfluidics and nanofluidics. Here, we report a basic nanofluidic…

Mesoscale and Nanoscale Physics · Physics 2025-11-05 Xichao Zhang , Jing Xia , Yan Zhou , Guoping Zhao , Xiaoxi Liu , Yongbing Xu , Masahito Mochizuki

When tiny soft ferromagnetic particles are placed along a liquid interface and exposed to a vertical magnetic field, the balance between capillary attraction and magnetic repulsion leads to self-organization into well-defined patterns.…

Soft Condensed Matter · Physics 2020-11-13 Ylona Collard , Galien Grosjean , Nicolas Vandewalle

In Nature, liquids often circulate in channels textured with leaflets, cilia or porous walls that deform with the flow. These soft structures are optimized to passively control flows and inspire the design of novel microfluidic and soft…

Soft Condensed Matter · Physics 2020-08-19 Martin Brandenbourger , Adrien Dangremont , Rudolf Sprik , Corentin Coulais

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

Many biological microswimmers locomote by periodically beating the densely-packed cilia on their cell surface in a wave-like fashion. While the swimming mechanisms of ciliated microswimmers have been extensively studied both from the…

Soft Condensed Matter · Physics 2023-06-22 Hanliang Guo , Hai Zhu , Ruowen Liu , Marc Bonnet , Shravan Veerapaneni

Direct mechanical coupling is known to be critical for establishing synchronization among cilia. However, the actual role of the connections is still elusive - partly because controlled experiments in live samples are challenging. Here, we…

Soft Condensed Matter · Physics 2023-12-27 Yiming Xia , Zixian Hu , Da Wei , Ke Chen , Yi Peng , Mingcheng Yang

In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this…

Biological Physics · Physics 2012-07-19 Christophe Eloy , Eric Lauga

Encapsulation of chemicals using polymer membranes enables to control their transport and delivery for applications such as agrochemistry or detergency. To rationalize the design of polymer capsules, it is necessary to understand how the…

Soft Condensed Matter · Physics 2018-12-18 Corentin Tregouët , Thomas Salez , Mathilde Reyssat , Cécile Monteux

Microorganisms develop coordinated beating patterns on surfaces lined with cilia known as metachronal waves. For a chain of cilia attached to a flat ciliate, it has been shown that hydrodynamic interactions alone can lead the system to…

Fluid Dynamics · Physics 2016-03-23 Babak Nasouri , Gwynn J. Elfring

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

Fluid Dynamics · Physics 2011-08-30 Sebastien Michelin , Eric Lauga

We present a microfluidic platform for two-dimensional manipulation of water droplets immersed in bulk oil-based ferrofluid. Although non-magnetic, the droplets are exclusively controlled by magnetic fields, without any pressure-driven…

Fluid Dynamics · Physics 2017-12-05 Georgios Katsikis , Alexandre Breant , Anatoly Rinberg , Manu Prakash

Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…