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The design of microfluidic devices is a cumbersome and tedious process that can be significantly improved by simulation. Methods based on Computational Fluid Dynamics (CFD) are considered state-of-the-art, but require extensive compute time…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Michel Takken , Robert Wille

We consider a finite-dimensional model for the motion of microscopic organisms whose propulsion exploits the action of a layer of cilia covering its surface. The model couples Newton's laws driving the organism, considered as a rigid body,…

Optimization and Control · Mathematics 2009-09-29 Mario Sigalotti , Jean-Claude Vivalda

The dynamics and motion of multi-ciliated microswimmers with a spherical body and a small number N (with 5 < N < 60) of cilia with length comparable to the body radius, is investigated by mesoscale hydrodynamics simulations. A metachronal…

Soft Condensed Matter · Physics 2024-06-03 Sebastian Rode , Jens Elgeti , Gerhard Gompper

Elastic filaments are vital to biological, physical and engineering systems, from cilia driving fluid in the lungs to artificial swimmers and micro-robotics. Simulating slender structures requires intricate balance of elastic, body, active,…

Biological Physics · Physics 2023-06-02 Paul Fuchter , Hermes Bloomfield-Gadêlha

Using a two-fluid model for viscoelastic polymer solutions, we study analytically fluid transport driven by a transverse, small amplitude traveling wave propagation. The pumping flow far from the waving boundary is shown to be strongly wave…

Biological Physics · Physics 2010-04-09 Hirofumi Wada

Large-scale microfluidic microsystems with complex three-dimensional (3D) configurations are highly in demand by both fundamental research and industrial application, holding the potentials for fostering a wide range of innovative…

Applied Physics · Physics 2020-01-13 Zijie Lin , Jian Xu , Yunpeng Song , Xiaolong Li , Peng Wang , Wei Chu , Zhenhua Wang , Ya Cheng

Pumps are indispensable for analytical applications and ensure controlled fluid movement. Syringe pumps are among today_s most prevalent liquid delivery systems, especially for high-pressure, stable, low-flow-rate microfluidic applications.…

Fluid Dynamics · Physics 2025-07-17 Moritz Leuthner , Oliver Hayden

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas

Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…

We consider a classical overdamped Brownian particle moving in a symmetric periodic potential. We show that a net particle flow can be produced by adiabatically changing two external periodic potentials with a spatial and a temporal phase…

Statistical Mechanics · Physics 2009-11-07 O. Usmani , E. Lutz , M. Buttiker

The performances of lubricated systems widely used in natural, biological, and artificial settings are traditionally dictated by their load bearing capacities. Here we unveil that, by exploiting a unique coupling between interfacial…

Fluid Dynamics · Physics 2022-07-26 Siddhartha Mukherjee , Jayabrata Dhar , Sunando DasGupta , Suman Chakraborty

Active swimmers are ubiquitous in nature, found in many diverse biological systems ranging from bacteria to vertebrate fish. Of particular importance are sperm cells which are swimmers that are crucial for the survival of many species…

Biological Physics · Physics 2017-11-15 James L. Kingsley , Utkan Demirci , Erkan Tuzel

Finding solutions for better mixing in microfluidics remains an important challenge, including understanding fundamental aspects of these processes. Here we investigate the magnetic micro-convection on water and miscible magnetic fluid…

To mimic the mechanical response of passive biological cilia in complex fluids, we study the bending dynamics of an anchored elastic fiber submitted to a dilute granular suspension under shear. We show that the bending fluctuations of the…

Microorganisms are able to overcome the thermal randomness of their surroundings by harvesting energy to navigate in viscous fluid environments. In a similar manner, synthetic colloidal microswimmers are capable of mimicking complex…

Amorphous glassy materials of diverse nature -- concentrated emulsions, granular materials, pastes, molecular glasses -- display complex flow properties, intermediate between solid and liquid, which are at the root of their use in many…

Materials Science · Physics 2008-07-04 J. Goyon , A. Colin , G. Ovarlez , A. Ajdari , L. Bocquet

Design of microfluidic biochips has led to newer challenges to the EDA community due to the availability of various flow-based architectures and the need for catering to diverse applications such as sample preparation, personalized…

Emerging Technologies · Computer Science 2021-07-28 Tapalina Banerjee , Sudip Poddar , Tsung-Yi Ho , Bhargab B. Bhattacharya

Contactless manipulation of small objects is essential for biomedical and chemical applications, such as cell analysis, assisted fertilisation, and precision chemistry. Established methods, including optical, acoustic, and magnetic…

Fluid Dynamics · Physics 2025-07-02 Lucas Amoudruz , Petr Karnakov , Petros Koumoutsakos

The research feld of magnonics proposes a low-energy wave-logic computation technology based on spin waves to complement the established CMOS technology and provide a basis for emerging unconventional computation architectures. However,…

Cilia and flagella are hair-like appendages that protrude from the surface of a variety of eukaryotic cells and deform in a wavelike fashion to transport fluids and propel cells. Motivated by the ubiquity of non-Newtonian fluids in biology,…

Fluid Dynamics · Physics 2014-03-19 J. Rodrigo Vélez-Cordero , Eric Lauga
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