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The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

In this manuscript, we present a robust method for glaucoma screening from fundus images using an ensemble of convolutional neural networks (CNNs). The pipeline comprises of first segmenting the optic disk and optic cup from the fundus…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Vismay Agrawal , Avinash Kori , Varghese Alex , Ganapathy Krishnamurthi

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Hui Xie , Weiyu Xu , Xiaodong Wu

Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images…

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

Accurate isolation and quantification of intraocular dimensions in the anterior segment (AS) of the eye using optical coherence tomography (OCT) images is important in the diagnosis and treatment of many eye diseases, especially angle…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Tan Hung Pham , Sripad Krishna Devalla , Aloysius Ang , Soh Zhi Da , Alexandre H. Thiery , Craig Boote , Ching-Yu Cheng , Victor Koh , Michael J. A. Girard

Purpose: To investigate the impact of optic nerve tortuosity (ONT), and the interaction of globe proptosis and globe size on retinal ganglion cell (RGC) thickness, using Retinal Nerve Fiber Layer (RNFL) thickness, across general, glaucoma,…

Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Huazhu Fu , Jun Cheng , Yanwu Xu , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Mayank Goswami

Objective: (1) To assess whether ONH biomechanics improves prediction of three progressive visual field loss patterns in glaucoma; (2) to use explainable AI to identify strain-sensitive ONH regions contributing to these predictions.…

Optical Coherence Tomography Angiography (OCTA) is a non-invasive and non-contacting imaging technique providing visualization of microvasculature of retina and optic nerve head in human eyes in vivo. The adequate image quality of OCTA is…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Yufei Wang , Yiqing Shen , Meng Yuan , Jing Xu , Bin Yang , Chi Liu , Wenjia Cai , Weijing Cheng , Wei Wang

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Purpose: The purpose of this study was to develop and evaluate rule-based algorithms to enhance the extraction of text data, including retinal nerve fiber layer (RNFL) values and other ganglion cell count (GCC) data, from Zeiss Cirrus…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Iyad Majid , Youchen Victor Zhang , Robert Chang , Sophia Y. Wang