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Depression is a common mental disorder worldwide which causes a range of serious outcomes. The diagnosis of depression relies on patient-reported scales and psychiatrist interview which may lead to subjective bias. In recent years, more and…
INTRODUCTION: The pharmacological treatment of Major Depressive Disorder (MDD) relies on a trial-and-error approach. We introduce an artificial intelligence (AI) model aiming to personalize treatment and improve outcomes, which was deployed…
There has been significant attention given to developing data-driven methods for tailoring patient care based on individual patient characteristics. Dynamic treatment regimes formalize this through a sequence of decision rules that map…
Model interpretability has become important to engenders appropriate user trust by providing the insight into the model prediction. However, most of the existing machine learning methods provide no interpretability for depression…
Major depressive disorder is a common mental disorder that affects almost 7% of the adult U.S. population. The 2017 Audio/Visual Emotion Challenge (AVEC) asks participants to build a model to predict depression levels based on the audio,…
Disorders of consciousness are a heterogeneous mixture of different diseases or injuries. Although some indicators and models have been proposed for prognostication, any single method when used alone carries a high risk of false prediction.…
We study a model of continuous opinion dynamics with both positive and negative mutual interaction. The model shows a continuous phase transition between a phase with consensus (order) and a phase having no consensus (disorder). The mean…
Depression poses serious public health risks, including suicide, underscoring the urgency of timely and scalable screening. Multimodal automatic depression detection (ADD) offers a promising solution; however, widely studied audio- and…
According to the World Health Organization (WHO), one in four people will be affected by mental disorders at some point in their lives. However, in many parts of the world, patients do not actively seek professional diagnosis because of…
Manic episodes of bipolar disorder can lead to uncritical behaviour and delusional psychosis, often with destructive consequences for those affected and their surroundings. Early detection and intervention of a manic episode are crucial to…
Transformer-based models have demonstrated exceptional performance across diverse domains, becoming the state-of-the-art solution for addressing sequential machine learning problems. Even though we have a general understanding of the…
The paper deals with disorders detection in the multivariate stochastic process. We consider the multidimensional Poisson process or the multivariate renewal process. This class of processes can be used as a description of the distributed…
The theory of slow manifolds is an important tool in the study of deterministic dynamical systems, giving a practical method by which to reduce the number of relevant degrees of freedom in a model, thereby often resulting in a considerable…
We present a stochastic differential equation model of suicidal progression in U.S. veterans, simulating transitions across mental health states under dynamic stress and covariate influence. Transition rates are modulated by an…
Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…
We develop a unified theory that encompasses the macroscopic dynamics of recurrent interactions of binary units within arbitrary network architectures. Using the martingale theory, our mathematical analysis provides a complete description…
Mental health is not a fixed trait but a dynamic process shaped by the interplay between individual dispositions and situational contexts. Building on interactionist and constructionist psychological theories, we develop interpretable…
The availability of mobile technologies has enabled the efficient collection prospective longitudinal, ecologically valid self-reported mood data from psychiatric patients. These data streams have potential for improving the efficiency and…
Estimating intervention effects in dynamical systems is crucial for outcome optimization. In medicine, such interventions arise in physiological regulation (e.g., cardiovascular system under fluid administration) and pharmacokinetics, among…
The abundance of data affords researchers to pursue more powerful computational tools to learn the dynamics of complex system, such as neural networks, engineered systems and social networks. Traditional machine learning approaches capture…