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Hyperspectral change detection (HCD) is one of the core applications of remote sensing images, holding significant research value in fields like environmental monitoring and disaster assessment. However, existing methods often suffer from…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Mingshuai Sheng , Bhatti Uzair Aslam , Junfeng Zhang , Siling Feng , Yonis Gulzar

Deep learning models lack shift invariance, making them sensitive to input shifts that cause changes in output. While recent techniques seek to address this for images, our findings show that these approaches fail to provide…

Machine Learning · Computer Science 2025-02-28 Berken Utku Demirel , Christian Holz

Histone modification is a vital epigenetic mechanism for transcriptional control in eukaryotes. High-throughput techniques have enabled whole-genome analysis of histone modifications in recent years. However, most studies assume one…

Genomics · Quantitative Biology 2014-05-12 Mengjie Chen , Haifan Lin , Hongyu Zhao

This paper deals with differentiable dynamical models congruent with neural process theories that cast brain function as the hierarchical refinement of an internal generative model explaining observations. Our work extends existing…

Machine Learning · Computer Science 2021-12-10 André Ofner , Sebastian Stober

Inverse protein folding generates valid amino acid sequences that can fold into a desired protein structure, with recent deep-learning advances showing strong potential and competitive performance. However, challenges remain, such as…

Biomolecules · Quantitative Biology 2025-07-29 Peizhen Bai , Filip Miljković , Xianyuan Liu , Leonardo De Maria , Rebecca Croasdale-Wood , Owen Rackham , Haiping Lu

We introduce Diff-DOPE, a 6-DoF pose refiner that takes as input an image, a 3D textured model of an object, and an initial pose of the object. The method uses differentiable rendering to update the object pose to minimize the visual error…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jonathan Tremblay , Bowen Wen , Valts Blukis , Balakumar Sundaralingam , Stephen Tyree , Stan Birchfield

Accurate time series prediction is challenging due to the inherent nonlinearity and sensitivity to initial conditions. We propose a novel approach that enhances neural network predictions through differential learning, which involves…

Machine Learning · Computer Science 2025-03-11 Akash Yadav , Eulalia Nualart

This paper presents NeurEPDiff, a novel network to fast predict the geodesics in deformation spaces generated by a well known Euler-Poincar\'e differential equation (EPDiff). To achieve this, we develop a neural operator that for the first…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Nian Wu , Miaomiao Zhang

Spatial transcriptomics (ST) bridges gene expression and tissue morphology but faces clinical adoption barriers due to technical complexity and prohibitive costs. While computational methods predict gene expression from H&E-stained…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ziqiao Weng , Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee AD Cooper , Weidong Cai , Bo Zhou

We present a general architecture of deep differentiable forest and its sparse attention mechanism. The differentiable forest has the advantages of both trees and neural networks. Its structure is a simple binary tree, easy to use and…

Machine Learning · Computer Science 2020-03-03 Yingshi Chen

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

Machine Learning · Computer Science 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

In many sequential tasks, a model needs to remember relevant events from the distant past to make correct predictions. Unfortunately, a straightforward application of gradient based training requires intermediate computations to be stored…

Machine Learning · Computer Science 2023-08-14 Artyom Sorokin , Nazar Buzun , Leonid Pugachev , Mikhail Burtsev

While deep learning-based methods for blind face restoration have achieved unprecedented success, they still suffer from two major limitations. First, most of them deteriorate when facing complex degradations out of their training data.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Zongsheng Yue , Chen Change Loy

Visuomotor imitation learning policies enable robots to efficiently acquire manipulation skills from visual demonstrations. However, as scene complexity and visual distractions increase, policies that perform well in simple settings often…

Artificial Intelligence · Computer Science 2025-11-11 Yuhang Dong , Haizhou Ge , Yupei Zeng , Jiangning Zhang , Beiwen Tian , Hongrui Zhu , Yufei Jia , Ruixiang Wang , Zhucun Xue , Guyue Zhou , Longhua Ma , Guanzhong Tian

Addressing uncertainty in Deep Learning (DL) is essential, as it enables the development of models that can make reliable predictions and informed decisions in complex, real-world environments where data may be incomplete or ambiguous. This…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Ayyub Alzahem , Wadii Boulila , Maha Driss , Anis Koubaa

As neural networks make their way into safety-critical systems, where misbehavior can lead to catastrophes, there is a growing interest in certifying the equivalence of two structurally similar neural networks. For example, compression…

Machine Learning · Computer Science 2020-09-22 Brandon Paulsen , Jingbo Wang , Jiawei Wang , Chao Wang

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Understanding the neural basis of behavior is a fundamental goal in neuroscience. Current research in large-scale neuro-behavioral data analysis often relies on decoding models, which quantify behavioral information in neural data but lack…

Neurons and Cognition · Quantitative Biology 2024-11-27 Yule Wang , Chengrui Li , Weihan Li , Anqi Wu

Diffusion and flow-based models have enabled significant progress in generation tasks across various modalities and have recently found applications in predictive learning. However, unlike typical generation tasks that encourage sample…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yu Zhang , Xingzhuo Guo , Haoran Xu , Jialong Wu , Mingsheng Long

Motivation: Deep learning architectures have recently demonstrated their power in predicting DNA- and RNA-binding specificities. Existing methods fall into three classes: Some are based on Convolutional Neural Networks (CNNs), others use…

Machine Learning · Computer Science 2019-01-31 Ameni Trabelsi , Mohamed Chaabane , Asa Ben Hur
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