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Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

Graphics · Computer Science 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju

Interpretable malware detection is crucial for understanding harmful behaviors and building trust in automated security systems. Traditional explainable methods for Graph Neural Networks (GNNs) often highlight important regions within a…

Cryptography and Security · Computer Science 2025-04-30 Hossein Shokouhinejad , Roozbeh Razavi-Far , Griffin Higgins , Ali A. Ghorbani

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Automated detection of sclerotic metastases (bone lesions) in Computed Tomography (CT) images has potential to be an important tool in clinical practice and research. State-of-the-art methods show performance of 79% sensitivity or…

Computer Vision and Pattern Recognition · Computer Science 2014-07-23 Holger R. Roth , Jianhua Yao , Le Lu , James Stieger , Joseph E. Burns , Ronald M. Summers

Fine-grained image classification (FGIC) is a challenging task in computer vision for due to small visual differences among inter-subcategories, but, large intra-class variations. Deep learning methods have achieved remarkable success in…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Asish Bera , Debotosh Bhattacharjee , Mita Nasipuri

Gaussian Graphical Models (GGMs) are widely used in high-dimensional data analysis to synthesize the interaction between variables. In many applications, such as genomics or image analysis, graphical models rely on sparsity and clustering…

Machine Learning · Statistics 2026-03-25 Do Edmond Sanou , Christophe Ambroise , Geneviève Robin

Recent studies in pathology foundation models have shown that scaling training data, diversifying cancer types, and increasing model size consistently improve their performance. However, giga-scale foundation models, which are trained on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Yesung Cho , Sungmin Lee , Geongyu Lee , Minkyung Lee , Jongbae Park , Dongmyung Shin

Staining is essential in cell imaging and medical diagnostics but poses significant challenges, including high cost, time consumption, labor intensity, and irreversible tissue alterations. Recent advances in deep learning have enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ziwang Xu , Lanqing Guo , Satoshi Tsutsui , Shuyan Zhang , Alex C. Kot , Bihan Wen

This paper introduces a set of cepstrum-based texture features for melanoma classification and validates their performance on dermoscopic images from the ISIC 2019 dataset. We propose applying gray-level co-occurrence matrix (GLCM)…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Keith Miller , Tristan Crawford , Jason Hagerty , William Stoecker , Ronald J. Stanley

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Vision-language models (VLMs) have shown considerable potential in digital pathology, yet their effectiveness remains limited for fine-grained, disease-specific classification tasks such as distinguishing between glomerular subtypes. The…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhenhao Guo , Rachit Saluja , Tianyuan Yao , Quan Liu , Yuankai Huo , Benjamin Liechty , David J. Pisapia , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Variously stained histology slices are routinely used by pathologists to assess extracted tissue samples from various anatomical sites and determine the presence or extent of a disease. Evaluation of sequential slides is expected to enable…

Image and Video Processing · Electrical Eng. & Systems 2019-04-29 Ludovic Venet , Sarthak Pati , Paul Yushkevich , Spyridon Bakas

Existing deep learning methods for radiology report generation enhance diagnostic efficiency but often overlook physician-informed medical priors. This leads to a suboptimal alignment between the structured explanations and disease…

Tissues and Organs · Quantitative Biology 2026-04-13 Aishik Konwer , Moinak Bhattacharya , Prateek Prasanna

In this paper, we study the problem of Generalized Category Discovery (GCD), which aims to cluster unlabeled data from both known and unknown categories using the knowledge of labeled data from known categories. Current GCD methods rely on…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Haiyang Zheng , Nan Pu , Wenjing Li , Nicu Sebe , Zhun Zhong

Detecting and segmenting dysfluencies is crucial for effective speech therapy and real-time feedback. However, most methods only classify dysfluencies at the utterance level. We introduce StutterCut, a semi-supervised framework that…

Sound · Computer Science 2025-08-05 Suhita Ghosh , Melanie Jouaiti , Jan-Ole Perschewski , Sebastian Stober

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Segmentation from renal pathological images is a key step in automatic analyzing the renal histological characteristics. However, the performance of models varies significantly in different types of stained datasets due to the appearance…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Ke Mei , Chuang Zhu , Lei Jiang , Jun Liu , Yuanyuan Qiao

Automated grading of diabetic retinopathy (DR) faces several critical challenges: subtle inter-grade visual distinctions in fine-grained lesion patterns, distributional discrepancies induced by heterogeneous imaging devices and acquisition…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Yiqun Wang

Gastrointestinal (GI) bleeding is a serious medical condition that presents significant diagnostic challenges, particularly in settings with limited access to healthcare resources. Wireless Capsule Endoscopy (WCE) has emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 S. Balasubramanian , Ammu Abhishek , Yedu Krishna , Darshan Gera

With the advancement of powerful image processing and machine learning techniques, CAD has become ever more prevalent in all fields of medicine including ophthalmology. Since optic disc is the most important part of retinal fundus image for…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Muhammad Naseer Bajwa , Muhammad Imran Malik , Shoaib Ahmed Siddiqui , Andreas Dengel , Faisal Shafait , Wolfgang Neumeier , Sheraz Ahmed