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Many modern deep learning applications require balancing multiple objectives that are often conflicting. Examples include multi-task learning, fairness-aware learning, and the alignment of Large Language Models (LLMs). This leads to…

Machine Learning · Computer Science 2025-08-07 Weiyu Chen , Baijiong Lin , Xiaoyuan Zhang , Xi Lin , Han Zhao , Qingfu Zhang , James T. Kwok

Despite the common usage of a canonical, data-independent, hemodynamic response function (HRF), it is known that the shape of the HRF varies across brain regions and subjects. This suggests that a data-driven estimation of this function…

Computational Engineering, Finance, and Science · Computer Science 2014-11-10 Fabian Pedregosa , Michael Eickenberg , Philippe Ciuciu , Bertrand Thirion , Alexandre Gramfort

Bi-level optimization, especially the gradient-based category, has been widely used in the deep learning community including hyperparameter optimization and meta-knowledge extraction. Bi-level optimization embeds one problem within another…

Machine Learning · Computer Science 2023-07-11 Can Chen , Xi Chen , Chen Ma , Zixuan Liu , Xue Liu

Multimodal neuroimaging grants a powerful in vivo window into the structure and function of the human brain. Recent methodological and conceptual advances have enabled investigations of the interplay between large-scale spatial trends, or…

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Early diagnosis of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) utilizing multi-modal magnetic resonance imaging (MRI) is a pivotal area of research. While various regional and connectivity features from functional…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Xiongri Shen , Zhenxi Song , Linling Li , Min Zhang , Lingyan Liang Honghai Liu , Demao Deng , Zhiguo Zhang

Limited amount of labelled training data are a common problem in medical imaging. This makes it difficult to train a well-generalised model and therefore often leads to failure in unknown domains. Hippocampus segmentation from magnetic…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 John Kalkhof , Camila González , Anirban Mukhopadhyay

In this paper, we propose a harmonized rotational gradient method, termed HRGrad, for simultaneously tackling multiscale time-dependent kinetic problems with varying small parameters. These parameters exhibit asymptotic transitions from…

Machine Learning · Computer Science 2026-04-28 Zhangyong Liang

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Representational Similarity Analysis (RSA) aims to explore similarities between neural activities of different stimuli. Classical RSA techniques employ the inverse of the covariance matrix to explore a linear model between the neural…

Neurons and Cognition · Quantitative Biology 2018-09-13 Xiaoliang Sheng , Muhammad Yousefnezhad , Tonglin Xu , Ning Yuan , Daoqiang Zhang

When do gradient-based explanation algorithms provide perceptually-aligned explanations? We propose a criterion: the feature attributions need to be aligned with the tangent space of the data manifold. To provide evidence for this…

Machine Learning · Computer Science 2024-07-16 Sebastian Bordt , Uddeshya Upadhyay , Zeynep Akata , Ulrike von Luxburg

Gradient-based iterative optimization methods are the workhorse of modern machine learning. They crucially rely on careful tuning of parameters like learning rate and momentum. However, one typically sets them using heuristic approaches…

Machine Learning · Computer Science 2025-12-05 Dravyansh Sharma

The joint alignment of multivariate functional data plays an important role in various fields such as signal processing, neuroscience and medicine, including the statistical analysis of data from wearable devices. Traditional methods often…

Signal Processing · Electrical Eng. & Systems 2023-12-18 Vi Thanh Pham , Jonas Bille Nielsen , Klaus Fuglsang Kofoed , Jørgen Tobias Kühl , Andreas Kryger Jensen

Decoding visual information from human brain activity has seen remarkable advancements in recent research. However, the diversity in cortical parcellation and fMRI patterns across individuals has prompted the development of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Guangyin Bao , Qi Zhang , Zixuan Gong , Jialei Zhou , Wei Fan , Kun Yi , Usman Naseem , Liang Hu , Duoqian Miao

Efficient beam alignment is fundamental to high-throughput and reliable connectivity in Vehicle-to-Everything (V2X) systems. However, conventional beam management in dynamic vehicular topologies incurs prohibitive alignment overhead and…

Signal Processing · Electrical Eng. & Systems 2026-04-24 Jiahui Liang , Shuoyao Wang , Shijian Gao

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

Decoding cognitive states from functional magnetic resonance imaging is central to understanding the functional organization of the brain. Within-subject decoding avoids between-subject correspondence problems but requires large sample…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Himanshu Aggarwal , Liza Al-Shikhley , Bertrand Thirion

Video-based person re-identification (re-ID) is an important research topic in computer vision. The key to tackling the challenging task is to exploit both spatial and temporal clues in video sequences. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-05-03 Yichao Yan , Jie Qin1 , Jiaxin Chen , Li Liu , Fan Zhu , Ying Tai , Ling Shao

Hyperparameter optimization in machine learning is often achieved using naive techniques that only lead to an approximate set of hyperparameters. Although techniques such as Bayesian optimization perform an intelligent search on a given…

Machine Learning · Computer Science 2023-06-21 Ankur Sinha , Satender Gunwal , Shivam Kumar

Gaussian Mixture Models (GMMs) are a standard tool in data analysis. However, they face problems when applied to high-dimensional data (e.g., images) due to the size of the required full covariance matrices (CMs), whereas the use of…

Machine Learning · Computer Science 2023-08-29 Alexander Gepperth