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In this paper we introduce a new hierarchical model for the simultaneous detection of brain activation and estimation of the shape of the hemodynamic response in multi-subject fMRI studies. The proposed approach circumvents a major…

Applications · Statistics 2015-11-13 David Degras , Martin A. Lindquist

The growing use of neuroimaging technologies generates a massive amount of biomedical data that exhibit high dimensionality. Tensor-based analysis of brain imaging data has been proved quite effective in exploiting their multiway nature.…

Numerical Analysis · Computer Science 2016-07-21 Christos Chatzichristos , Eleftherios Kofidis , Giannis Kopsinis , Sergios Theodoridis

Bilevel optimization problems are receiving increasing attention in machine learning as they provide a natural framework for hyperparameter optimization and meta-learning. A key step to tackle these problems is the efficient computation of…

Machine Learning · Statistics 2025-05-20 Riccardo Grazzi , Massimiliano Pontil , Saverio Salzo

While reinforcement learning for large language model alignment has progressed rapidly in recent years, transferring these paradigms to high-stakes medical question answering reveals a fundamental paradigm mismatch. Reinforcement Learning…

Artificial Intelligence · Computer Science 2026-03-03 Tianxiang Xu , Jiayi Liu , Yixuan Tong , Jialu Xu , Yunqing Wei , Kaiwen Feng , PanPan Hou , Kangping Yin , Jiyuan Hu , Hao Zhou , Zhenxin Ma , Jian Xu , Guanjun Jiang

An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree of heterogeneity of shape and appearance. Traditional…

Brain encoding and decoding aims to understand the relationship between external stimuli and brain activities, and is a fundamental problem in neuroscience. In this article, we study latent embedding alignment for brain encoding and…

Methodology · Statistics 2026-03-24 Shuoxun Xu , Zhanhao Yan , Lexin Li

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang

Bilevel reinforcement learning (RL), which features intertwined two-level problems, has attracted growing interest recently. The inherent non-convexity of the lower-level RL problem is, however, to be an impediment to developing bilevel…

Optimization and Control · Mathematics 2025-02-28 Yan Yang , Bin Gao , Ya-xiang Yuan

Deep learning models for semantic segmentation of images require large amounts of data. In the medical imaging domain, acquiring sufficient data is a significant challenge. Labeling medical image data requires expert knowledge.…

Machine Learning · Computer Science 2018-10-24 Micah J Sheller , G Anthony Reina , Brandon Edwards , Jason Martin , Spyridon Bakas

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

In recent years, a variety of gradient-based methods have been developed to solve Bi-Level Optimization (BLO) problems in machine learning and computer vision areas. However, the theoretical correctness and practical effectiveness of these…

Machine Learning · Computer Science 2022-01-04 Risheng Liu , Pan Mu , Xiaoming Yuan , Shangzhi Zeng , Jin Zhang

Machine learning problems with multiple objective functions appear either in learning with multiple criteria where learning has to make a trade-off between multiple performance metrics such as fairness, safety and accuracy; or, in…

Machine Learning · Computer Science 2024-03-20 Heshan Fernando , Han Shen , Miao Liu , Subhajit Chaudhury , Keerthiram Murugesan , Tianyi Chen

Magnetic resonance imaging (MRI) is known to have reduced signal-to-noise ratios (SNR) at lower field strengths, leading to signal degradation when producing a low-field MRI image from a high-field one. Therefore, reconstructing a…

Image and Video Processing · Electrical Eng. & Systems 2023-05-05 Zhuo-Xu Cui , Congcong Liu , Chentao Cao , Yuanyuan Liu , Jing Cheng , Qingyong Zhu , Yanjie Zhu , Haifeng Wang , Dong Liang

The medical image is characterized by the inter-class indistinction, high variability, and noise, where the recognition of pixels is challenging. Unlike previous self-attention based methods that capture context information from one level,…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Fei Ding , Gang Yang , Jinlu Liu , Jun Wu , Dayong Ding , Jie Xv , Gangwei Cheng , Xirong Li

The development of algorithms to accurately decode neural information has long been a research focus in the field of neuroscience. Brain decoding typically involves training machine learning models to map neural data onto a preestablished…

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Decoding visual-semantic information from brain signals, such as functional MRI (fMRI), across different subjects poses significant challenges, including low signal-to-noise ratio, limited data availability, and cross-subject variability.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Ruizhe Zheng , Lichao Sun

Semantic segmentation in very high resolution (VHR) aerial images is one of the most challenging tasks in remote sensing image understanding. Most of the current approaches are based on deep convolutional neural networks (DCNNs). However,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-16 Ruigang Niu , Xian Sun , Yu Tian , Wenhui Diao , Kaiqiang Chen , Kun Fu

Due to the substantial computational cost, training state-of-the-art deep neural networks for large-scale datasets often requires distributed training using multiple computation workers. However, by nature, workers need to frequently…

Machine Learning · Computer Science 2018-02-21 Yusuke Tsuzuku , Hiroto Imachi , Takuya Akiba

The problem of complex data analysis is a central topic of modern statistical science and learning systems and is becoming of broader interest with the increasing prevalence of high-dimensional data. The challenge is to develop statistical…

Machine Learning · Statistics 2018-03-05 Faicel Chamroukhi , Hien D. Nguyen
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