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Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Open-Access and Collaborative Consumer Health Vocabulary (OAC CHV, or CHV for short), is a collection of medical terms written in plain English. It provides a list of simple, easy, and clear terms that laymen prefer to use rather than an…

Computation and Language · Computer Science 2020-04-15 Mohammed Ibrahim , Susan Gauch , Omar Salman , Mohammed Alqahatani

In this work, we consider the medical concept normalization problem, i.e., the problem of mapping a disease mention in free-form text to a concept in a controlled vocabulary, usually to the standard thesaurus in the Unified Medical Language…

Computation and Language · Computer Science 2018-11-30 Elena Tutubalina , Zulfat Miftahutdinov , Sergey Nikolenko , Valentin Malykh

Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

We present a cross-linguistic study that aims to quantify vowel harmony using data-driven computational modeling. Concretely, we define an information-theoretic measure of harmonicity based on the predictability of vowels in a natural…

Computation and Language · Computer Science 2023-08-10 Julius Steuer , Badr Abdullah , Johann-Mattis List , Dietrich Klakow

Biomedical research requires large, diverse samples to produce unbiased results. Automated methods for matching variables across datasets can accelerate this process. Research in this area has been limited, primarily focusing on lexical…

Computation and Language · Computer Science 2024-11-06 Zexu Li , Suraj P. Prabhu , Zachary T. Popp , Shubhi S. Jain , Vijetha Balakundi , Ting Fang Alvin Ang , Rhoda Au , Jinying Chen

Word embeddings are a popular approach to unsupervised learning of word relationships that are widely used in natural language processing. In this article, we present a new set of embeddings for medical concepts learned using an extremely…

Computation and Language · Computer Science 2019-08-21 Andrew L. Beam , Benjamin Kompa , Allen Schmaltz , Inbar Fried , Griffin Weber , Nathan P. Palmer , Xu Shi , Tianxi Cai , Isaac S. Kohane

In this work, we consider the medical concept normalization problem, i.e., the problem of mapping a health-related entity mention in a free-form text to a concept in a controlled vocabulary, usually to the standard thesaurus in the Unified…

Computation and Language · Computer Science 2023-11-21 Zulfat Miftahutdinov , Elena Tutubalina

A unified mathematical language for medicine and science will be presented. Using this language, models for DNA replication, protein synthesis, chemical reactions, neurons and a cardiac cycle of a heart have been built. Models for Turing…

Quantitative Methods · Quantitative Biology 2014-09-18 Patrick St-Amant

Precision Medicine (PM) is an emerging approach that appears with the impression of changing the existing paradigm of medical practice. Recent advances in technological innovations and genetics, and the growing availability of health data…

Computers and Society · Computer Science 2019-11-05 Muhammad Afzal , S. M. Riazul Islam , Maqbool Hussain , Sungyoung Lee

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

A large number of embeddings trained on medical data have emerged, but it remains unclear how well they represent medical terminology, in particular whether the close relationship of semantically similar medical terms is encoded in these…

Computation and Language · Computer Science 2020-03-26 Claudia Schulz , Damir Juric

Medical vision-language models (VLMs) combine computer vision (CV) and natural language processing (NLP) to analyze visual and textual medical data. Our paper reviews recent advancements in developing VLMs specialized for healthcare,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Iryna Hartsock , Ghulam Rasool

Medical vision-and-language models (MVLMs) have attracted substantial interest due to their capability to offer a natural language interface for interpreting complex medical data. Their applications are versatile and have the potential to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Qi Chen , Ruoshan Zhao , Sinuo Wang , Vu Minh Hieu Phan , Anton van den Hengel , Johan Verjans , Zhibin Liao , Minh-Son To , Yong Xia , Jian Chen , Yutong Xie , Qi Wu

Although traditional statistical techniques and machine learning methods have contributed significantly to genetics and, in particular, inherited disease diagnosis, they often struggle with complex, high-dimensional data, a challenge now…

Machine Learning · Computer Science 2025-08-29 Anton Changalidis , Yury Barbitoff , Yulia Nasykhova , Andrey Glotov

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

The advancement in healthcare has shifted focus toward patient-centric approaches, particularly in self-care and patient education, facilitated by access to Electronic Health Records (EHR). However, medical jargon in EHRs poses significant…

Computation and Language · Computer Science 2024-10-28 Zonghai Yao , Nandyala Siddharth Kantu , Guanghao Wei , Hieu Tran , Zhangqi Duan , Sunjae Kwon , Zhichao Yang , README annotation team , Hong Yu

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li
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