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Knowledge probing is crucial for understanding the knowledge transfer mechanism behind the pre-trained language models (PLMs). Despite the growing progress of probing knowledge for PLMs in the general domain, specialised areas such as…

Computation and Language · Computer Science 2022-05-24 Zaiqiao Meng , Fangyu Liu , Ehsan Shareghi , Yixuan Su , Charlotte Collins , Nigel Collier

Clinical predictions using clinical data by computational methods are common in bioinformatics. However, clinical predictions using information from genomics datasets as well is not a frequently observed phenomenon in research. Precision…

Genomics · Quantitative Biology 2021-06-25 Moeez M. Subhani , Ashiq Anjum

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

This research paper outlines the development and implementation of a novel Clinical Decision Support System (CDSS) that integrates AI predictive modeling with medical knowledge bases. It utilizes the quantifiable information elements in lab…

Artificial Intelligence · Computer Science 2026-03-17 Muhammad Hammad Maqsood , Mubashir Sajid , Khubaib Ahmed , Muhammad Usamah Shahid , Muddassar Farooq

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

Information Retrieval · Computer Science 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Adapting language models (LMs) to novel domains is often achieved through fine-tuning a pre-trained LM (PLM) on domain-specific data. Fine-tuning introduces new knowledge into an LM, enabling it to comprehend and efficiently perform a…

Computation and Language · Computer Science 2024-03-29 Micheal Abaho , Danushka Bollegala , Gary Leeming , Dan Joyce , Iain E Buchan

Prompt engineering is crucial for harnessing the potential of large language models (LLMs), especially in the medical domain where specialized terminology and phrasing is used. However, the efficacy of prompt engineering in the medical…

Computation and Language · Computer Science 2025-07-22 Jamil Zaghir , Marco Naguib , Mina Bjelogrlic , Aurélie Névéol , Xavier Tannier , Christian Lovis

Healthcare domain generates a lot of unstructured and semi-structured text. Natural Language processing (NLP) has been used extensively to process this data. Deep Learning based NLP especially Large Language Models (LLMs) such as BERT have…

Computation and Language · Computer Science 2023-01-11 Kunal Suri , Atul Singh , Prakhar Mishra , Swapna Sourav Rout , Rajesh Sabapathy

Language is a valuable source of clinical information in Alzheimer's Disease, as it declines concurrently with neurodegeneration. Consequently, speech and language data have been extensively studied in connection with its diagnosis. This…

Artificial Intelligence · Computer Science 2020-10-14 Sofia de la Fuente Garcia , Craig Ritchie , Saturnino Luz

Large Vision-Language Models (LVLMs) are capable of handling diverse data types such as imaging, text, and physiological signals, and can be applied in various fields. In the medical field, LVLMs have a high potential to offer substantial…

Individuals are increasingly generating substantial personal health and lifestyle data, e.g. through wearables and smartphones. While such data could transform preventative care, its integration into clinical practice is hindered by its…

Human-Computer Interaction · Computer Science 2026-02-16 Pavithren V S Pakianathan , Rania Islambouli , Diogo Branco , Albrecht Schmidt , Tiago Guerreiro , Jan David Smeddinck

Large language models (LLMs) have been widely adopted in various downstream task domains. However, their abilities to directly recall and apply factual medical knowledge remains under-explored. Most existing medical QA benchmarks assess…

Computation and Language · Computer Science 2025-08-20 Jiaxi Li , Yiwei Wang , Kai Zhang , Yujun Cai , Bryan Hooi , Nanyun Peng , Kai-Wei Chang , Jin Lu

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Precision medicine is accelerating rapidly in the field of health research. This includes fitting predictive models for individual patients based on patient similarity in an attempt to improve model performance. We propose an algorithm…

Methodology · Statistics 2025-02-07 Tatiana Krikella , Joel A. Dubin

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

Computation and Language · Computer Science 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

Large Language Models (LLMs) have ushered in a new era in Natural Language Processing, but their massive size demands effective compression techniques for practicality. Although numerous model compression techniques have been investigated,…

Computation and Language · Computer Science 2025-05-06 Hongchuan Zeng , Hongshen Xu , Lu Chen , Kai Yu

Precision Medicine (PM) transforms the traditional "one-drug-fits-all" paradigm by customising treatments based on individual characteristics, and is an emerging topic for HCI research on digital health. A key element of PM, the Polygenic…

Human-Computer Interaction · Computer Science 2025-02-03 Yuhao Sun , Albert Tenesa , John Vines

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

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