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Analyzing time series in the frequency domain enables the development of powerful tools for investigating the second-order characteristics of multivariate processes. Parameters like the spectral density matrix and its inverse, the coherence…

Methodology · Statistics 2024-01-19 Jonas Krampe , Efstathios Paparoditis

Analysis of structural and functional connectivity (FC) of human brains is of pivotal importance for diagnosis of cognitive ability. The Human Connectome Project (HCP) provides an excellent source of neural data across different regions of…

Applications · Statistics 2020-07-10 Satwik Acharyya , Zhengwu Zhang , Anirban Bhattacharya , Debdeep Pati

Mathematical models are becoming increasingly important in magnetic resonance imaging (MRI), as they provide a mechanistic approach for making a link between tissue microstructure and signals acquired using the medical imaging instrument.…

Medical Physics · Physics 2021-06-10 Viktor Vegh , Shahrzad Moinian , Qianqian Yang , David C. Reutens

We study the distribution of brain source from the most advanced brain imaging technique, Magnetoencephalography (MEG), which measures the magnetic fields outside the human head produced by the electrical activity inside the brain. Common…

Applications · Statistics 2019-08-13 Zhigang Yao , Zengyan Fan , Masahito Hayashi , William F. Eddy

The major sources of abundant data are constantly expanding with the available data collection methodologies in various applications - medical, insurance, scientific, bio-informatics and business. These data sets may be distributed…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-24 Aruna Govada , Sanjay K. Sahay

In clinical practice and biomedical research, measurements are often collected sparsely and irregularly in time while the data acquisition is expensive and inconvenient. Examples include measurements of spine bone mineral density, cancer…

Machine Learning · Statistics 2021-08-05 Łukasz Kidziński , Trevor Hastie

A common feature of methods for analyzing samples of probability density functions is that they respect the geometry inherent to the space of densities. Once a metric is specified for this space, the Fr\'echet mean is typically used to…

Methodology · Statistics 2018-12-20 Alexander Petersen , Hans-Georg Müller

Scaling temporal dynamics in functional MRI (fMRI) signals have been evidenced for a decade as intrinsic characteristics of ongoing brain activity (Zarahn et al., 1997). Recently, scaling properties were shown to fluctuate across brain…

Statistics Theory · Mathematics 2013-08-21 P. Ciuciu , G. Varoquaux , P. Abry , S. Sadaghiani , A. Kleinschmidt

A core goal of functional neuroimaging is to study how the environment is processed in the brain. The mainstream paradigm involves concurrently measuring a broad spectrum of brain responses to a small set of environmental features…

Neurons and Cognition · Quantitative Biology 2021-06-14 Pedro F. da Costa , Rianne Haartsen , Elena Throm , Luke Mason , Anna Gui , Robert Leech , Emily J. H. Jones

Estimation of covariance matrices is a fundamental problem in multivariate statistics. Recently, growing efforts have focused on incorporating covariate effects into these matrices, facilitating subject-specific estimation. Despite these…

Methodology · Statistics 2026-04-10 Rakheon Kim , Emma Jingfei Zhang

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart

The fetal cortical plate (CP) undergoes drastic morphological changes during the in utero development. Therefore, CP growth and folding patterns are key indicator in the assessment of the brain development and maturation. Magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Priscille de Dumast , Hamza Kebiri , Vincent Dunet , Mériam Koob , Meritxell Bach Cuadra

Resting-state functional Magnetic Resonance Imaging (fMRI) is a powerful imaging technique for studying functional development of the brain in utero. However, unpredictable and excessive movement of fetuses has limited clinical application…

Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

Methodology · Statistics 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

Fr\'echet mean and variance provide a way of obtaining mean and variance for general metric space valued random variables and can be used for statistical analysis of data objects that lie in abstract spaces devoid of algebraic structure and…

Statistics Theory · Mathematics 2019-10-22 Paromita Dubey , Hans-Georg Müller

Axon diameter and myelin thickness affect the conduction velocity of action potentials in the nervous system. Imaging them non-invasively with MRI-based methods is thus valuable for studying brain microstructure and function. Electron…

Functional magnetic resonance imaging (fMRI) is a crucial technology for gaining insights into cognitive processes in humans. Data amassed from fMRI measurements result in volumetric data sets that vary over time. However, analysing such…

Neurons and Cognition · Quantitative Biology 2020-10-23 Bastian Rieck , Tristan Yates , Christian Bock , Karsten Borgwardt , Guy Wolf , Nicholas Turk-Browne , Smita Krishnaswamy

Fetal functional Magnetic Resonance Imaging (fMRI) has emerged as a powerful tool for investigating brain development in utero, holding promise for generating developmental disease biomarkers and supporting prenatal diagnosis. However, to…