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Automated fetal brain extraction from full-uterus MRI is a challenging task due to variable head sizes, orientations, complex anatomy, and prevalent artifacts. While deep-learning (DL) models trained on synthetic images have been successful…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Javid Dadashkarimi , Valeria Pena Trujillo , Camilo Jaimes , Lilla Zöllei , Malte Hoffmann

Functional magnetic resonance imaging or functional MRI (fMRI) is a very popular tool used for differing brain regions by measuring brain activity. It is affected by physiological noise, such as head and brain movement in the scanner from…

Methodology · Statistics 2023-10-30 Fangyijie Wang , Michael Salter-Townshend

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Functional Magnetic Resonance Imaging is a noninvasive tool for studying cerebral function. Many factors challenge activation detection, especially in low-signal scenarios that arise in the performance of high-level cognitive tasks. We…

Methodology · Statistics 2019-05-07 Israel Almodóvar-Rivera , Ranjan Maitra

The segregation and integration of infant brain networks undergo tremendous changes due to the rapid development of brain function and organization. Traditional methods for estimating brain modularity usually rely on group-averaged…

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Fetal brain MRI is useful for diagnosing brain abnormalities but is challenged by fetal motion. The current protocol for T2-weighted fetal brain MRI is not robust to motion so image volumes are degraded by inter- and intra- slice motion…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Junshen Xu , Sayeri Lala , Borjan Gagoski , Esra Abaci Turk , P. Ellen Grant , Polina Golland , Elfar Adalsteinsson

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

We propose a nonparametric model for time series with missing data based on low-rank matrix factorization. The model expresses each instance in a set of time series as a linear combination of a small number of shared basis functions.…

The brain is a system operating on multiple time scales, and characterisation of dynamics across time scales remains a challenge. One framework to study such dynamics is that of fractal geometry. However, currently there exists no…

Neurons and Cognition · Quantitative Biology 2018-12-12 Lucas G. S. França , José G. V. Miranda , Marco Leite , Niraj K. Sharma , Matthew C. Walker , Louis Lemieux , Yujiang Wang

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique known for its ability to capture brain activity non-invasively and at fine spatial resolution (2-3mm). Cortical surface fMRI (cs-fMRI) is a recent development of fMRI…

Applications · Statistics 2023-12-29 Huy Dang , Marzia Cremona , Nicole Lazar , Francesca Chiaromonte

Fetal brain MRI is becoming an increasingly relevant complement to neurosonography for perinatal diagnosis, allowing fundamental insights into fetal brain development throughout gestation. However, uncontrolled fetal motion and…

Covariance estimation is essential yet underdeveloped for analyzing multivariate functional data. We propose a fast covariance estimation method for multivariate sparse functional data using bivariate penalized splines. The tensor-product…

Methodology · Statistics 2019-06-11 Cai Li , Luo Xiao , Sheng Luo

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

All neuroimaging modalities have their own strengths and limitations. A current trend is toward interdisciplinary approaches that use multiple imaging methods to overcome limitations of each method in isolation. At the same time…

Methodology · Statistics 2023-03-30 Pratim Guha Niyogi , Martin A. Lindquist , Tapabrata Maiti

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Functional connectivity (FC) derived from functional magnetic resonance imaging (fMRI) data offers vital insights for understanding brain function and neurological and psychiatric disorders. Unsupervised clustering methods are desired to…

Methodology · Statistics 2025-12-04 Yixi Xu , Yi Zhao

Purpose: Functional Magnetic Resonance Imaging (fMRI) data acquired through resting-state studies have been used to obtain information about the spontaneous activations inside the brain. One of the approaches for analysis and interpretation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Harshit Parmar , Brian Nutter , Rodney Long , Sameer Antani , Sunanda Mitra