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The rapid progress of generative models such as GANs and diffusion models has led to the widespread proliferation of AI-generated images, raising concerns about misinformation, privacy violations, and trust erosion in digital media.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Jiazhen Yan , Ziqiang Li , Fan Wang , Boyu Wang , Ziwen He , Zhangjie Fu

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

Automatic brain tumor segmentation method plays an extremely important role in the whole process of brain tumor diagnosis and treatment. In this paper, we propose a multi-step cascaded network which takes the hierarchical topology of the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-26 Xiangyu Li , Gongning Luo , Kuanquan Wang

Previously, image interpretation in radiology relied heavily on manual methods. However, manual classification of brain tumor medical images is time-consuming and labor-intensive. Even with shallow convolutional neural network models, the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yufeng Li , Wenchao Zhao , Bo Dang , Weimin Wang

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Although CNNs are widely considered as the state-of-the-art models in various applications of image analysis, one of the main challenges still open is the training of a CNN on high resolution images. Different strategies have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Nadia Brancati , Giuseppe De Pietro , Daniel Riccio , Maria Frucci

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Yu-Min Chung , Chuan-Shen Hu , Austin Lawson , Clifford Smyth

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

Histopathological cancer diagnosis is based on visual examination of stained tissue slides. Hematoxylin and eosin (H\&E) is a standard stain routinely employed worldwide. It is easy to acquire and cost effective, but cells and tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Zhaoyang Xu , Xingru Huang , Carlos Fernández Moro , Béla Bozóky , Qianni Zhang

Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Hematoxylin- and eosin (H&E) stained whole-slide images (WSIs) are the foundation of diagnosis of cancer. In recent years, development of deep learning-based methods in computational pathology enabled the prediction of biomarkers directly…

Deep neural networks for chest X-ray classification achieve strong average performance, yet often underperform for specific demographic subgroups, raising critical concerns about clinical safety and equity. Existing debiasing methods…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Darakshan Rashid , Raza Imam , Dwarikanath Mahapatra , Brejesh Lall

Efficient and precise classification of histological cell nuclei is of utmost importance due to its potential applications in the field of medical image analysis. It would facilitate the medical practitioners to better understand and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 S H Shabbeer Basha , Soumen Ghosh , Kancharagunta Kishan Babu , Shiv Ram Dubey , Viswanath Pulabaigari , Snehasis Mukherjee

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

Lymph node metastasis is one of the most significant diagnostic indicators in breast cancer, which is traditionally observed under the microscope by pathologists. In recent years, computerized histology diagnosis has become one of the most…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Huangjing Lin , Hao Chen , Qi Dou , Liansheng Wang , Jing Qin , Pheng-Ann Heng

In recent years, the use of deep learning (DL) methods, including convolutional neural networks (CNNs) and vision transformers (ViTs), has significantly advanced computational pathology, enhancing both diagnostic accuracy and efficiency.…

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…