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Computational pathology models rarely utilise data that will not be available for inference. This means most models cannot learn from highly informative data such as additional immunohistochemical (IHC) stains and spatial transcriptomics.…
It is of great significance to diagnose Invasive Ductal Carcinoma (IDC) in early stage, which is the most common subtype of breast cancer. Although the powerful models in the Computer-Aided Diagnosis (CAD) systems provide promising results,…
Histological staining is a vital step used to diagnose various diseases and has been used for more than a century to provide contrast to tissue sections, rendering the tissue constituents visible for microscopic analysis by medical experts.…
Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…
Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…
Pathologists diagnose and grade prostate cancer by examining tissue from needle biopsies on glass slides. The cancer's severity and risk of metastasis are determined by the Gleason grade, a score based on the organization and morphology of…
Interpreting traditional B-mode ultrasound images can be challenging due to image artifacts (e.g., shadowing, speckle), leading to low sensitivity and limited diagnostic accuracy. While Magnetic Resonance Imaging (MRI) has been proposed as…
Automatic segmentation of liver tumors in medical images is crucial for the computer-aided diagnosis and therapy. It is a challenging task, since the tumors are notoriously small against the background voxels. This paper proposes a new…
In recent years, tons of research has been conducted on Single Image Super-Resolution (SISR). However, to the best of our knowledge, few of these studies are mainly focused on compressed images. A problem such as complicated compression…
Manually inspecting polyps from a colonoscopy for colorectal cancer or performing a biopsy on skin lesions for skin cancer are time-consuming, laborious, and complex procedures. Automatic medical image segmentation aims to expedite this…
The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…
Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…
Deep learning models, e.g. supervised Encoder-Decoder style networks, exhibit promising performance in medical image segmentation, but come with a high labelling cost. We propose TriSegNet, a semi-supervised semantic segmentation framework.…
Deep learning models that are trained on histopathological images obtained from a single lab and/or scanner give poor inference performance on images obtained from another scanner/lab with a different staining protocol. In recent years,…
Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…
Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream…
The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…
Background and Objective: Gastric cancer has turned out to be the fifth most common cancer globally, and early detection of gastric cancer is essential to save lives. Histopathological examination of gastric cancer is the gold standard for…
Foundation models in computational pathology promise to unlock the development of new clinical decision support systems and models for precision medicine. However, there is a mismatch between most clinical analysis, which is defined at the…
A novel deep learning architecture (XmasNet) based on convolutional neural networks was developed for the classification of prostate cancer lesions, using the 3D multiparametric MRI data provided by the PROSTATEx challenge. End-to-end…