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Related papers: Gradient Sensing via Cell Communication

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We present a systematic evaluation framework - thirty-seven analyses, 153 statistical tests, four cell types, two perturbation modalities - for assessing mechanistic interpretability in single-cell foundation models. Applying this framework…

Genomics · Quantitative Biology 2026-02-20 Ihor Kendiukhov

In this paper, we consider the bacterial point-to-point communication problem with one transmitter and one receiver by considering the ligand receptor binding process. The most commonly investigated signalling model, referred to as the…

Information Theory · Computer Science 2015-04-17 Gholamali Aminian , Mahtab Mirmohseni , Masoumeh Nasiri Kenari , Faramarz Fekri

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathematical model, we find that sufficiently strong communication…

Biological Physics · Physics 2025-12-18 Soutick Saha , Sean Fancher , Andrew Mugler

It is well known that the kinetics of an intracellular biochemical network is stochastic. This is due to intrinsic noise arising from the random timing of biochemical reactions in the network as well as due to extrinsic noise stemming from…

Subcellular Processes · Quantitative Biology 2019-06-05 Emma M. Keizer , Bjorn Bastian , Robert W. Smith , Ramon Grima , Christian Fleck

Molecular Communications (MC) uses molecules as information carriers between nanomachines. MC channel in practice can be crowded with different types of molecules, i.e., ligands, which can have similar binding properties causing severe…

Emerging Technologies · Computer Science 2019-08-13 Murat Kuscu , Ozgur B. Akan

Optical molecular sensing techniques are often limited by the refractive index change associated with the probed interactions. In this work, we present a closed form analytical model to estimate the magnitude of optical refractive index…

Applied Physics · Physics 2017-12-04 Harish Sasikumar , Manoj M. Varma

Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains. There…

Molecular Networks · Quantitative Biology 2016-12-28 Tahir I. Yusufaly , James Q. Boedicker

The "chemical bond" is a central concept in molecular sciences, but there is no consensus as to what a bond actually is. Therefore, a variety of bonding models have been developed, each defining the structure of molecules in a different…

Chemical Physics · Physics 2016-05-03 Amanda Morgenstern

Distributed deep learning has recently been attracting more attention in remote sensing (RS) applications due to the challenges posed by the increased amount of open data that are produced daily by Earth observation programs. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Weiying Xie , Zixuan Wang , Jitao Ma , Daixun Li , Yunsong Li

As generative artificial intelligence (GAI) models continue to evolve, their generative capabilities are increasingly enhanced and being used extensively in content generation. Beyond this, GAI also excels in data modeling and analysis,…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Jiacheng Wang , Hongyang Du , Dusit Niyato , Jiawen Kang , Shuguang Cui , Xuemin Shen , Ping Zhang

When cells measure concentrations of chemical signals, they may average multiple measurements over time in order to reduce noise in their measurements. However, when cells are in a environment that changes over time, past measurements may…

Cell Behavior · Quantitative Biology 2025-03-05 Aparajita Kashyap , Wei Wang , Brian A. Camley

Practitioners apply neural networks to increasingly complex problems in natural language processing, such as syntactic parsing and semantic role labeling that have rich output structures. Many such structured-prediction problems require…

Computation and Language · Computer Science 2019-04-23 Jay Yoon Lee , Sanket Vaibhav Mehta , Michael Wick , Jean-Baptiste Tristan , Jaime Carbonell

Cell-cell communication is often achieved by secreted signaling molecules that bind membrane-bound receptors. A common class of such receptors are G-protein coupled receptors, where extracellular binding induces changes on the membrane…

Subcellular Processes · Quantitative Biology 2020-03-04 Steven Blaber , David A. Sivak

In a molecular communication network, transmitters and receivers communicate by using signalling molecules. At the receivers, the signalling molecules react, via a chain of chemical reactions, to produce output molecules. The counts of…

Molecular Networks · Quantitative Biology 2020-07-23 Chun Tung Chou

When an electron is scattered by a tightly-focused laser beam in vacuum, the intensity gradient is a critical factor to influence the electron dynamics, for example, the electron energy exchange with the laser fields as have been explored…

To successfully navigate chemical gradients, microorganisms need to predict how the ligand concentration changes in space. Due to their limited size, they do not take a spatial derivative over their body length but rather a temporal…

Molecular Networks · Quantitative Biology 2024-02-09 Age J. Tjalma , Pieter Rein ten Wolde

This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-01-21 Adam Noel , Karen C. Cheung , Robert Schober

Communication is crucial in multi-agent reinforcement learning when agents are not able to observe the full state of the environment. The most common approach to allow learned communication between agents is the use of a differentiable…

Machine Learning · Computer Science 2022-04-13 Astrid Vanneste , Simon Vanneste , Kevin Mets , Tom De Schepper , Siegfried Mercelis , Steven Latré , Peter Hellinckx

Mutual information (MI) is a general measure of statistical dependence with widespread application across the sciences. However, estimating MI between multi-dimensional variables is challenging because the number of samples necessary to…

Quantitative Methods · Quantitative Biology 2025-03-06 Gokul Gowri , Xiao-Kang Lun , Allon M. Klein , Peng Yin

Leveraging the inherent connection between sensing systems and wireless communications can improve their overall performance and is the core objective of joint communications and sensing. For effective communications, one has to frequently…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Benedikt Böck , Franz Weißer , Michael Baur , Wolfgang Utschick