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Related papers: Magnetic Resonance Spectroscopy Quantification usi…

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Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for biomedical detection. However, it is challenging to accurately quantify metabolites with proton MRS due to serious overlaps of metabolite signals, imperfections…

Magnetic resonance spectroscopy (MRS) is an established technique for studying tissue metabolism, particularly in central nervous system disorders. While powerful and versatile, MRS is often limited by challenges associated with data…

Quantitative Methods · Quantitative Biology 2024-08-29 Christopher J. Wu , Lawrence S. Kegeles , Jia Guo

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

Magnetic Resonance Spectroscopic Imaging (MRSI) is a clinical imaging modality for measuring tissue metabolite levels in-vivo. An accurate estimation of spectral parameters allows for better assessment of spectral quality and metabolite…

Computer Vision and Pattern Recognition · Computer Science 2018-05-28 Dhritiman Das , Eduardo Coello , Rolf F Schulte , Bjoern H Menze

Quantification of metabolites from magnetic resonance spectra (MRS) has many applications in medicine and psychology, but remains a challenging task despite considerable research efforts. For example, the neurotransmitter…

Image and Video Processing · Electrical Eng. & Systems 2019-09-10 M. Chandler , C. Jenkins , S. M. Shermer , F. C. Langbein

Magnetic resonance spectroscopic imaging is a widely available imaging modality that can non-invasively provide a metabolic profile of the tissue of interest, yet is challenging to integrate clinically. One major reason is the expensive,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 John LaMaster , Dhritiman Das , Florian Kofler , Jason Crane , Yan Li , Tobias Lasser , Bjoern H Menze

Magnetic resonance spectroscopy (MRS) is used to quantify metabolites in vivo and estimate biomarkers for conditions ranging from neurological disorders to cancers. Quantifying low-concentration metabolites such as GABA…

Signal Processing · Electrical Eng. & Systems 2026-02-25 Zien Ma , S. M. Shermer , Oktay Karakuş , Frank C. Langbein

Magnetic resonance spectroscopy (MRS) is a non-invasive technique to measure the metabolic composition of tissues, offering valuable insights into neurological disorders, tumor detection, and other metabolic dysfunctions. However, accurate…

Machine Learning · Statistics 2025-05-09 Julian P. Merkofer , Dennis M. J. van de Sande , Alex A. Bhogal , Ruud J. G. van Sloun

Magnetic resonance spectroscopy (MRS) is an important clinical imaging method for diagnosis of diseases. MRS spectrum is used to observe the signal intensity of metabolites or further infer their concentrations. Although the magnetic…

Nuclear Magnetic Resonance (NMR) spectra are widely used in metabolomics to obtain profiles of metabolites dissolved in biofluids such as cell supernatants. Methods for estimating metabolite concentrations from these spectra are presently…

Methodology · Statistics 2012-05-16 William Astle , Maria De Iorio , Sylvia Richardson , David Stephens , Timothy Ebbels

Nuclear magnetic resonance (NMR) spectroscopy serves as an indispensable tool in chemistry and biology but often suffers from long experimental time. We present a proof-of-concept of application of deep learning and neural network for…

Medical Physics · Physics 2019-05-15 Xiaobo Qu , Yihui Huang , Hengfa Lu , Tianyu Qiu , Di Guo , Tatiana Agback , Vladislav Orekhov , Zhong Chen

Magnetic Resonance Spectroscopy (MRS) provides valuable information to help with the identification and understanding of brain tumors, yet MRS is not a widely available medical imaging modality. Aiming to counter this issue, this research…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Nathan J Olliverre , Guang Yang , Gregory Slabaugh , Constantino Carlos Reyes-Aldasoro , Eduardo Alonso

Nuclear magnetic resonance spectroscopy (MRS) allows for the determination of atomic structures and concentrations of different chemicals in a biochemical sample of interest. MRS is used in vivo clinically to aid in the diagnosis of several…

Medical Physics · Physics 2021-05-04 Zohaib Iqbal , Dan Nguyen , M. Albert Thomas , Steve Jiang

Magnetic Resonance Spectroscopic Imaging (MRSI) is a valuable tool for studying metabolic activities in the human body, but the current applications are limited to low spatial resolutions. The existing deep learning-based MRSI…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Siyuan Dong , Gilbert Hangel , Wolfgang Bogner , Georg Widhalm , Karl Rössler , Siegfried Trattnig , Chenyu You , Robin de Graaf , John Onofrey , James Duncan

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

Background: Magnetic resonance spectroscopy (MRS) enables non-invasive detection and measurement of biochemicals and metabolites. However, MRS has low signal-to-noise ratio (SNR) when concentrations of metabolites are in the range of the…

Medical Physics · Physics 2023-03-30 Jing Wang , Bing Ji , Yang Lei , Tian Liu , Hui Mao , Xiaofeng Yang

In vivo H nuclear magnetic resonance (NMR) spectroscopy is an important tool for performing non-invasive quantitative assessments of brain tumour glucose metabolism. Brain tumours are considered fast-growth tumours because of their high…

Biological Physics · Physics 2010-10-15 Alejandro Chinea Manrique de Lara

Detecting and quantifying products of cellular metabolism using Mass Spectrometry (MS) has already shown great promise in many biological and biomedical applications. The biggest challenge in metabolomics is annotation, where measured…

Machine Learning · Computer Science 2020-10-12 Hao Zhu , Liping Liu , Soha Hassoun

Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…

Medical Physics · Physics 2023-10-31 Dinor Nagar , Nikita Vladimirov , Christian T. Farrar , Or Perlman

Magnetic resonance imaging (MRI) is extensively used for diagnosis and image-guided therapeutics. Due to hardware, physical and physiological limitations, acquisition of high-resolution MRI data takes long scan time at high system cost, and…

Medical Physics · Physics 2018-10-17 Qing Lyu , Chenyu You , Hongming Shan , Ge Wang
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