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Magnetic resonance (MR) image re-parameterization refers to the process of generating via simulations of an MR image with a new set of MRI scanning parameters. Different parameter values generate distinct contrast between different tissues,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 Abhijeet Narang , Abhigyan Raj , Mihaela Pop , Mehran Ebrahimi

Obtaining magnetic resonance images (MRI) with high resolution and generating quantitative image-based biomarkers for assessing tissue biochemistry is crucial in clinical and research applications. How- ever, acquiring quantitative…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Akshay Chaudhari , Zhongnan Fang , Jin Hyung Lee , Garry Gold , Brian Hargreaves

Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor problems for people with a detrimental effect on the functioning of the nervous system. In order to diagnose MS, multiple screening methods have been…

Many developmental processes, such as plasticity and aging, or pathological processes such as neurological diseases are characterized by modulations of specific cellular types and their microstructures. Diffusion-weighted Magnetic Resonance…

Medical Physics · Physics 2019-03-26 Marco Palombo , Noam Shemesh , Itamar Ronen , Julien Valette

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

Magnetic resonance imaging is a powerful imaging modality that can provide versatile information but it has a bottleneck problem "slow imaging speed". Reducing the scanned measurements can accelerate MR imaging with the aid of powerful…

Image and Video Processing · Electrical Eng. & Systems 2020-12-17 Shanshan Wang , Taohui Xiao , Qiegen Liu , Hairong Zheng

Accurate quantification of metabolites in magnetic resonance spectroscopy (MRS) is challenged by low signal-to-noise ratio (SNR), overlapping metabolites, and various artifacts. Particularly, unknown and unparameterized baseline effects…

Signal Processing · Electrical Eng. & Systems 2024-10-15 Julian P. Merkofer , Dennis M. J. van de Sande , Sina Amirrajab , Kyung Min Nam , Ruud J. G. van Sloun , Alex A. Bhogal

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

Purpose: Proton magnetic resonance spectroscopic imaging ($^1$H MRSI) enables the mapping of whole-brain metabolites concentrations in-vivo. However, a long-standing problem for its clinical applicability is the metabolic quantification,…

Surface-enhanced Raman spectroscopy (SERS) is a potential fast and inexpensive method of analyte quantification, which can be combined with deep learning to discover biomarker-disease relationships. This study aims to address present…

Quantitative Methods · Quantitative Biology 2024-11-14 Jihan K. Zaki , Jakub Tomasik , Jade A. McCune , Sabine Bahn , Pietro Liò , Oren A. Scherman

Objctives: This work aimed to statistically compare the metabolite quantification of human brain magnetic resonance spectroscopy (MRS) between the deep learning method QNet and the classical method LCModel through an easy-to-use intelligent…

Magnetic Resonance Imaging (MRI) is important in clinic to produce high resolution images for diagnosis, but its acquisition time is long for high resolution images. Deep learning based MRI super resolution methods can reduce scan time…

Image and Video Processing · Electrical Eng. & Systems 2022-09-08 Ziyan Lin , Zihao Chen

Magnetic Resonance Spectroscopic Imaging (MRSI) is a powerful tool for non-invasive mapping of brain metabolites, providing critical insights into neurological conditions. However, its utility is often limited by missing or corrupted data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Tan-Hanh Pham , Ovidiu C. Andronesi , Xianqi Li , Kim-Doang Nguyen

Since the concept of Deep Learning (DL) was formally proposed in 2006, it had a major impact on academic research and industry. Nowadays, DL provides an unprecedented way to analyze and process data with demonstrated great results in…

Medical Physics · Physics 2020-04-06 Dicheng Chen , Zi Wang , Di Guo , Vladislav Orekhov , Xiaobo Qu

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert…

Image and Video Processing · Electrical Eng. & Systems 2020-03-03 Ismail Irmakci , Syed Muhammad Anwar , Drew A. Torigian , Ulas Bagci

Quantitative MRI is highly desirable in terms of intrinsic tissue parameters such as T1, T2 and proton density. This approach promises to minimize diagnostic variability and differentiate normal and pathological tissues by comparing tissue…

Medical Physics · Physics 2018-06-21 Qing Lyu , Ge Wang

In MR fingerprinting (MRF) reconstruction, measured data is pattern-matched to simulated signals to extract quantitative tissue parameters. A critical drawback to this approach is the exponentially increasing compute time for mapping of…

Medical Physics · Physics 2024-07-17 Victoria Y. Yu , Kathryn R. Tringale , Ricardo Otazo , Ouri Cohen

Magnetic resonance spectroscopic imaging (SI) is a unique imaging technique that provides biochemical information from in vivo tissues. The 1H spectra acquired from several spatial regions are quantified to yield metabolite concentrations…

Medical Physics · Physics 2019-10-23 Zohaib Iqbal , Dan Nguyen , Gilbert Hangel , Stanislav Motyka , Wolfgang Bogner , Steve Jiang

Nuclear Magnetic Resonance (NMR) spectroscopy leverages nuclear magnetization to probe molecules' chemical environment, structure, and dynamics, with applications spanning from pharmaceuticals to the petroleum industry. Despite its utility,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-14 Sen Yan , Fabrizio Gabellieri , Etienne Goffinet , Filippo Castiglione , Thomas Launey