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In considering evolution of transcribed regions, regulatory modules, and other genomic loci of interest, we are often faced with a situation in which the number of allelic states greatly exceeds the population size. In this limit, the…

Populations and Evolution · Quantitative Biology 2016-07-27 Pavel Khromov , Constantin D. Malliaris , Alexandre V. Morozov

We are interested in modelling Darwinian evolution, resulting from the interplay of phenotypic variation and natural selection through ecological interactions. Our models are rooted in the microscopic, stochastic description of a population…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Régis Ferrière , Sylvie Méléard

Many studies have analyzed how variability in reproductive success affects fitness. However, each study tends to focus on a particular problem, leaving unclear the overall structure of variability in populations. This fractured conceptual…

Populations and Evolution · Quantitative Biology 2011-11-08 Steven A. Frank

In the absence of selection, the structure of allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical patterns of molecular variation. Along with coalescent…

Populations and Evolution · Quantitative Biology 2011-05-30 Michael M. Desai , Lauren E. Nicolaisen , Aleksandra M. Walczak , Joshua B. Plotkin

In evolutionary processes, population structure has a substantial effect on natural selection. Here, we analyze how motion of individuals affects constant selection in structured populations. Motion is relevant because it leads to changes…

Populations and Evolution · Quantitative Biology 2017-10-10 Madison S. Krieger , Alex McAvoy , Martin A. Nowak

In a geographically distributed population, assortative clustering plays an important role in evolution by modifying local environments. To examine its effects in a linear habitat, we consider a one-dimensional grid of cells, where each…

Populations and Evolution · Quantitative Biology 2021-03-16 Sunhee Chae , Nahyeon Lee , Seung Ki Baek , Hyeong-Chai Jeong

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

A probabilistic reconstruction of genealogies in a polyploid population (from 2x to 4x) is investigated, by considering genetic data analyzed as the probability of allele presence in a given genotype. Based on the likelihood of all possible…

Populations and Evolution · Quantitative Biology 2018-11-29 Frédéric Proïa , Fabien Panloup , Chiraz Trabelsi , Jérémy Clotault

We introduce a population dynamics model, where individual genomes are represented by bit-strings. Selection is described by death probabilities which depend on these genomes, and new individuals continuously replace the ones that die,…

Statistical Mechanics · Physics 2009-11-10 P. M. C. de Oliveira , J. S. Sa' Martins , D. Stauffer , S. Moss de Oliveira

We analyse a family of two-types Wright-Fisher models with selection in a random environment and skewed offspring distribution. We provide a calculable criterion to quantify the impact of different shapes of selection on the fate of the…

Probability · Mathematics 2025-02-10 Adrián González Casanova , Dario Spanò , Maite Wilke-Berenguer

Standard evolutionary theories of aging and mortality, implicitly based on assumptions of spatial averaging, hold that natural selection cannot favor shorter lifespan without direct compensating benefit to individual reproductive success.…

Populations and Evolution · Quantitative Biology 2015-06-15 Justin Werfel , Donald E. Ingber , Yaneer Bar-Yam

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

We investigate through numerical simulations the effect of selection on two summary statistics for nucleotide variation in a sample of two genes from a population of N asexually reproducing haploid individuals. One is the mean time since…

Statistical Mechanics · Physics 2009-10-31 P. R. A. Campos , M. T. Sonoda , J. F. Fontanari

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

We consider an exactly solvable model of branching random walk with random selection, which describes the evolution of a population with $N$ individuals on the real line. At each time step, every individual reproduces independently, and its…

Probability · Mathematics 2018-10-09 Aser Cortines , Bastien Mallein

This article is a presentation of specific recent results describing scaling limits of individual-based models. Thanks to them, we wish to relate the time-scales typical of demographic dynamics and natural selection to the parameters of the…

Probability · Mathematics 2023-08-01 Aurélien Velleret

A simulation model of a population having internal (genetic) structure is presented. The population is subject to selection pressure coming from the environment which is the same in the whole system but changes in time. Reproduction has a…

Adaptation and Self-Organizing Systems · Physics 2012-08-31 Andrzej Pekalski , Marcel Ausloos

A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at…

Populations and Evolution · Quantitative Biology 2015-06-16 Alexey Yanchukov , Stephen R. Proulx

We consider a neutral haploid population whose generations are not overlapping and whose size is large and constantly of $N$ individuals. Any generation is replaced by a new one and any individual has a single parent. We do not choose the…

Populations and Evolution · Quantitative Biology 2009-11-11 Maurizio Serva