Related papers: Monodisperse versus polydisperse ultrasound contra…
Contrast-enhanced ultrasound (CEUS) presents distinct advantages in diagnostic echography. Utilizing microbubbles (MBs) as conventional contrast agents enhances vascular visualization and organ perfusion, facilitating real-time,…
Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of the encapsulated microbubbles under the action of an ultrasound field are…
Ultrasound contrast agents comprise gas microbubbles surrounded by stabilising elastic or viscoelastic shells. Microbubbles containing liquid or solid cores are referred to as antibubbles. The manufacturing process of long-lived antibubbles…
The field of contrast-enhanced ultrasound (CEUS) combines nonlinear, resonant microbubbles (MBs) with dedicated pulse sequences to reveal the vascular function of organs. Clinical ultrasound contrast agents consist of polydisperse MB…
While the acoustic properties of solid foams have been abundantly characterized, sound propagation in liquid foams remains poorly understood. Recent studies have investigated the transmission of ultrasound through three-dimensional…
Contrast microbubbles (contrast agents) were initially developed to increase the contrast of the image in ultrasound imaging. These microbubbles consist of a gas core encapsulated by a layer of protein or lipid to stabilize them against…
Acoustic characterization of ultrasound contrast agents (UCAs, coated microbubbles) relies on the attenuation theory that assumes the UCAs oscillate linearly at sufficiently low excitation pressures. Effective shell parameters of the UCAs…
In the paper, we succeeded to freeze-dry monodisperse microbubbles without degrading their size and acoustic properties. We used microfluidic technology to generate highly monodisperse (coefficient of variation, CV<5%) microbubbles and…
The scattering of ultrasound from bubbles of micrometer-sized radius, such as used in contrast enhancers for ultrasound diagnostics, is studied. We show that sound scattering and ``active'' emission of sound from oscillating bubbles are not…
Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…
Ultrasound contrast imaging is a specialized imaging technique that applies microbubble contrast agents to traditional medical sonography, providing real-time visualization of blood flow and vessels. Gas-filled microbubbles are injected…
Contrast enhanced ultrasound is a radiation-free imaging modality which uses encapsulated gas microbubbles for improved visualization of the vascular bed deep within the tissue. It has recently been used to enable imaging with unprecedented…
Subharmonics emitted from microbubble-based ultrasound contrast agents (UCA) are considered as a noninvasive indicator for diagnostic applications in medical fields. Contrast ultrasound imaging using the modality of subharmonics could be…
Monodisperse lipid-coated microbubbles are a promising route to unlock the full potential of ultrasound contrast agents for medical diagnosis and therapy. Here, we present a stand-alone lab-on-a-chip instrument that allows microbubbles to…
The oscillations of ultrasound contrast agents are of particular importance to the understanding of the propagation of acoustic waves in the bubbly liquids (suspensions of ultrasound contrast agents). Acoustic waves propagating in bubbly…
Ultrasound offers promising applications in biology and chemistry, but quantifying local ultrasound conditions remains challenging due to the lack of non-invasive measurement tools. We introduce antibubbles as novel optical reporters of…
We analyze mathematically the acoustic imaging modality using bubbles as contrast agents. These bubbles are modeled by mass densities and bulk moduli enjoying contrasting scales. These contrasting scales allow them to resonate at certain…
Results of the measurements of sound speed and attenuation in a bubbly medium are reported. Monodisperse bubble solutions are sonicated with broadband ultrasound pulses with pressure amplitudes ranging between 12.5-100 kPa. Fundamental…
Subharmonic response from contrast microbubbles as a function of ambient overpressure is numerically investigated for subharmonic aided noninvasive estimation of local organ level blood pressure. Three different interfacial rheological…
The attenuation of low-intensity acoustic waves in the suspension of ultrasound contrast agents (UCAs, microbubbles) is determined by the oscillation of the microbubbles in the medium. This bubble-induced attenuation is a linear phenomenon…