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A prototype flash analog-to-digital readout system for cosmic ray detection at energies below 10^18 eV has been designed and tested at Columbia University Nevis Laboratories. The electronics consist of an FADC module that digitizes 16…

Instrumentation and Detectors · Physics 2007-05-23 S. BenZvi , S. Westerhoff , J. Ban , W. Sippach

Efficient imaging of biomolecules, 2D materials and electromagnetic fields depends on retrieval of the phase of transmitted electrons. We demonstrate a method to measure phase in a scanning transmission electron microscope using a…

Many lung diseases require detailed visualisation for accurate diagnosis and treatment. High-resolution computed tomography (CT) is the gold-standard technique for non-invasive lung disease detection, but it presents a risk to the patient…

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

Instrumentation and Detectors · Physics 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

Recently, X-ray interferometers with more than one phase grating have been developed for differential phase contrast (DPC) imaging. In this study, a novel framework is developed to predict such interferometers' angular sensitivity responses…

Instrumentation and Detectors · Physics 2020-06-25 Jianwei Chen , Jiecheng Yang , Peiping Zhu , Ting Su , Huitao Zhang , Hairong Zheng , Dong Liang , Yongshuai Ge

Purpose: Grating-based imaging (GBI) and edge-illumination (EI) are two promising types of XPCI as the conventional x-ray sources can be directly utilized. For GBI and EI systems, the phase-stepping acquisition with multiple exposures at a…

Medical Physics · Physics 2022-01-19 Chengpeng Wu , Yuxiang Xing , Li Zhang , Zhiqiang Chen , Xiaohua Zhu , Xi Zhang , Hewei Gao

We present a novel way of wavefront sensing using a commercially available, continuous-wave time-of-flight camera with QVGA-resolution. This CMOS phase camera is capable of sensing externally modulated light sources with frequencies up to…

Instrumentation and Detectors · Physics 2021-08-18 Erik Muñiz , Varun Srivastava , Subham Vidyant , Stefan W. Ballmer

Two-dimensional Talbot array illuminators (TAIs) were designed, fabricated, and evaluated for high-resolution high-contrast x-ray phase imaging of soft tissue at 10-20keV. The TAIs create intensity modulations with a high compression ratio…

X-ray micro tomography is a non-destructive, three-dimensional inspection technique applied across a vast range of fields and disciplines, ranging from research to industrial, encompassing engineering, biology and medical research.…

Graphene based photo-detecting has received great attentions and the performance of such detector is stretching to both ends of high sensitivity and ultra-fast response. However, limited by the current photo-gating mechanism, the price for…

Instrumentation and Detectors · Physics 2016-09-23 Xitao Guo , Wenhui Wang , Haiyan Nan , Yuanfang Yu , Jie Jiang , Weiwei Zhao , Jinhuan Li , Zainab Zafar , Nan Xiang , Zhonghua Ni , Weida Hu , Yumeng You , Zhenhua Ni

X-ray imaging, traditionally relying on attenuation contrast, struggles to differentiate materials with similar attenuation coefficients like soft tissues. X-ray phase contrast imaging (XPCI) and dark-field (DF) imaging provide enhanced…

Medical Physics · Physics 2025-06-05 Jingcheng Yuan , Mini Das

Biological soft tissues encountered in clinical and pre-clinical imaging mainly consist of light element atoms, and their composition is nearly uniform with little density variation. Thus, x-ray attenuation imaging suffers from low image…

Medical Physics · Physics 2011-06-28 Wenxiang Cong , Atsushi Momose , Ge Wang

X-ray imaging is a prevalent technique for non-invasively visualizing the interior of the human body and opaque instruments. In most commercial x-ray modalities, an image is formed by measuring the x-rays that pass through the object of…

Medical Physics · Physics 2023-05-23 A. Ben Yehuda , O. Sefi , Y. Klein , R. H Shukrun , H. Schwartz , E. Cohen , S. Shwartz

A simple optical method is presented for identifying and measuring the effective optical properties of nanometer-thick, graphene-based materials, based on the use of substrates consisting of a thin dielectric layer on silicon. High contrast…

Optical interconnects are becoming attractive alternatives to electrical wiring in intra- and inter-chip communication links. Particularly, the integration with silicon complementary metal-oxide-semiconductor (CMOS) technology has received…

Mesoscale and Nanoscale Physics · Physics 2013-09-18 Andreas Pospischil , Markus Humer , Marco M. Furchi , Dominic Bachmann , Romain Guider , Thomas Fromherz , Thomas Mueller

A Compton camera is the most promising approach for gamma-ray detection in the energy region from several hundred keV to MeV, especially for application in high energy astrophysics. In order to obtain good angular resolution, semiconductor…

Cross-grating phase microscopy (CGM) is a quantitative phase microscopy technique based on the association of a 2-dimensional diffraction grating (cross-grating) and a regular camera sensor, separated by a millimetric distance. This simple…

Optics · Physics 2024-11-04 Baptiste Marthy , Guillaume Baffou

A fully automated system for interpreting abdominal computed tomography (CT) scans with multiple phases of contrast enhancement requires an accurate classification of the phases. This work aims at developing and validating a precise, fast…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Binh T. Dao , Thang V. Nguyen , Hieu H. Pham , Ha Q. Nguyen

The integrated optical circuit is a promising architecture for the realization of complex quantum optical states and information networks. One element that is required for many of these applications is a high-efficiency photon detector…

This study describes a new approach for material decomposition in x-ray imaging, utilising phase contrast to both increase sensitivity to weakly-attenuating samples and to act as a complementary measurement to attenuation, therefore…