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Most existing methods handle cell instance segmentation problems directly without relying on additional detection boxes. These methods generally fails to separate touching cells due to the lack of global understanding of the objects. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Jingru Yi , Pengxiang Wu , Qiaoying Huang , Hui Qu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Yixiong Liang , Zhihong Tang , Meng Yan , Jialin Chen , Qing Liu , Yao Xiang

Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Navid Alemi Koohababni , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

In this paper, we propose an automatic brain tumor segmentation approach (e.g., PixelNet) using a pixel-level convolutional neural network (CNN). The model extracts feature from multiple convolutional layers and concatenate them to form a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Mobarakol Islam , Hongliang Ren

In this paper we present a methodology that uses convolutional neural networks (CNNs) for segmentation by iteratively growing predicted mask regions in each coordinate direction. The CNN is used to predict class probability scores in a…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 John Lagergren , Erica Rutter , Kevin Flores

Nucleus segmentation is a challenging task due to the crowded distribution and blurry boundaries of nuclei. Recent approaches represent nuclei by means of polygons to differentiate between touching and overlapping nuclei and have…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Shengcong Chen , Changxing Ding , Minfeng Liu , Jun Cheng , Dacheng Tao

Object detection systems based on the deep convolutional neural network (CNN) have recently made ground- breaking advances on several object detection benchmarks. While the features learned by these high-capacity neural networks are…

Computer Vision and Pattern Recognition · Computer Science 2016-01-15 Yuting Zhang , Kihyuk Sohn , Ruben Villegas , Gang Pan , Honglak Lee

Spatial arrangement of cells of various types, such as tumor infiltrating lymphocytes and the advancing edge of a tumor, are important features for detecting and characterizing cancers. However, convolutional neural networks (CNNs) do not…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Shrey Gadiya , Deepak Anand , Amit Sethi

Star trackers are one of the most accurate celestial sensors used for absolute attitude determination. The devices detect stars in captured images and accurately compute their projected centroids on an imaging focal plane with subpixel…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Hongrui Zhao , Michael F. Lembeck , Adrian Zhuang , Riya Shah , Jesse Wei

Nuclear segmentation is important and frequently demanded for pathology image analysis, yet is also challenging due to nuclear crowdedness and possible occlusion. In this paper, we present a novel bottom-up method for nuclear segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Jiahui Li , Zhiqiang Hu , Shuang Yang

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Breast cancer is considered as the most fatal type of cancer among women worldwide and it is crucially important to be diagnosed at its early stages. In the current study, we aim to represent a fast and efficient framework which consists of…

Computer Vision and Pattern Recognition · Computer Science 2019-05-13 Parvin Yousefikamal

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Computerized detection of colonic polyps remains an unsolved issue because of the wide variation in the appearance, texture, color, size, and presence of the multiple polyp-like imitators during colonoscopy. In this paper, we propose a deep…

Computer Vision and Pattern Recognition · Computer Science 2020-08-18 Tariq Rahim , Syed Ali Hassan , Soo Young Shin

Instance segmentation is of great importance for many biological applications, such as study of neural cell interactions, plant phenotyping, and quantitatively measuring how cells react to drug treatment. In this paper, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Jingru Yi , Pengxiang Wu , Hui Tang , Bo Liu , Qiaoying Huang , Hui Qu , Lianyi Han , Wei Fan , Daniel J. Hoeppner , Dimitris N. Metaxas

[Abriged] Astronomical Wide Field Imaging performed with new large format CCD detectors poses data reduction problems of unprecedented scale which are difficult to deal with traditional interactive tools. We present here NExt (Neural…

Astrophysics · Physics 2009-10-31 S. Andreon , G. Gargiulo , G. Longo , R. Tagliaferri , N. Capuano

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Cell detection and segmentation is fundamental for all downstream analysis of digital pathology images. However, obtaining the pixel-level ground truth for single cell segmentation is extremely labor intensive. To overcome this challenge,…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Alireza Chamanzar , Yao Nie

Recently, deep convolutional neural networks have shown good results for image recognition. In this paper, we use convolutional neural networks with a finder module, which discovers the important region for recognition and extracts that…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Yusei Miura , Tetsuya Sakurai , Claus Aranha , Toshiya Senda , Ryuichi Kato , Yusuke Yamada