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Polymer properties are inherently multi-scale in nature, where delicate local interaction details play a key role in describing their global conformational behavior. In this context, deriving coarse-grained (CG) multi-scale models for…

This work presents a novel framework governing the development of an efficient, accurate, and transferable coarse-grained (CG) model of a polyether material. The proposed framework combines the two fundamentally different classical…

A hallmark of meso-scale interfacial fluids is the multi-faceted, scale-dependent interfacial energy, which often manifests different characteristics across the molecular and continuum scale. The multi-scale nature imposes a challenge to…

Computational Physics · Physics 2023-02-22 Pei Ge , Linfeng Zhang , Huan Lei

Poly(ethylene oxide)-$\textit{b}$-poly(butylmethacrylate) (PEO-$\textit{b}$-PBMA) copolymers have recently been identified as excellent building blocks for the synthesis of hierarchical nanoporous materials. Nevertheless, while experiments…

Soft Condensed Matter · Physics 2021-06-01 Gerardo Campos-Villalobos , Flor R. Siperstein , Arvin Charles , Alessandro Patti

We critically discuss and review the general ideas behind single- and multi-site coarse-grained (CG) models as applied to macromolecular solutions in the dilute and semi-dilute regime. We first consider single-site models with zero-density…

Soft Condensed Matter · Physics 2015-10-28 Giuseppe D'Adamo , Roberto Menichetti , Andrea Pelissetto , Carlo Pierleoni

The present work concerns the transferability of coarse-grained (CG) modeling in reproducing the dynamic properties of the reference atomistic systems across a range of parameters. In particular, we focus on implicit-solvent CG modeling of…

Computational Engineering, Finance, and Science · Computer Science 2021-03-22 Zhan Ma , Shu Wang , Minhee Kim , Kaibo Liu , Chun-Long Chen , Wenxiao Pan

A coarse-grained model is developed to allow large-scale molecular dynamics (MD) simulations of a branched polyetherimide derived from two backbone monomers [4,4'-bisphenol A dianhydride (BPADA) and m-phenylenediamine (MPD)], a chain…

Materials Science · Physics 2021-01-15 Chengyuan Wen , Roy Odle , Shengfeng Cheng

A temperature (T)-dependent coarse-grained (CG) Hamiltonian of polyethylene glycol/oxide (PEG/PEO) in aqueous solution is reported to be used in implicit-solvent material models in a wide temperature (i.e., solvent quality) range. The…

Chemical Physics · Physics 2017-10-26 Richard Chudoba , Jan Heyda , Joachim Dzubiella

In this paper, we present a new coarse-grained (CG) model for poly (alpha-peptoid)s that is compatible with the MARTINI CG FF. In the proposed model, CG poly (alpha-peptoid) is composed by a CG backbone (here we select polysarcosine as the…

Chemical Physics · Physics 2019-03-06 Peiyuan Gao , Alex Tartakovsky

We present a systematic coarse-graining (CG) strategy for many particle molecular systems based on cluster expansion techniques. We construct a hierarchy of coarse-grained Hamiltonians with interaction potentials consisting of two, three…

Soft Condensed Matter · Physics 2017-10-11 Anastasios Tsourtis , Vagelis Harmandaris , Dimitrios Tsagkarogiannis

Structural and thermodynamic consistency of coarse-graining models across multiple length scales is essential for the predictive role of multi-scale modeling and molecular dynamic simulations that use mesoscale descriptions. Our approach is…

Soft Condensed Matter · Physics 2014-07-04 J. McCarty , A. J. Clark , J. Copperman , M. G. Guenza

The most popular and universally predictive protein simulation models employ all-atom molecular dynamics (MD), but they come at extreme computational cost. The development of a universal, computationally efficient coarse-grained (CG) model…

We have developed a coarse-grained (CG) model of a polymer-clay system consisting of organically modified montmorillonite nanoclay as the nanoparticle in accordance with the MARTINI forcefield. We have used mechanical properties and…

Soft Condensed Matter · Physics 2019-07-16 Parvez khan , Gaurav Goel

A challenging topic in materials engineering is the development of numerical models that can accurately predict material properties with atomistic accuracy, matching the scale and level of detail achieved by experiments. In this regard,…

Soft Condensed Matter · Physics 2024-10-31 Francesco Maria Bellussi , Matteo Ricci , Matteo Fasano , Otello Maria Roscioni

Conjugated organic molecules play a central role in a wide range of optoelectronic devices, including organic light-emitting diodes, organic field-effect transistors, and organic solar cells. A major bottleneck in the computational design…

A coarse-graining strategy, previously developed for polymer solutions, is extended here to mixtures of linear polymers and hard-sphere colloids. In this approach groups of monomers are mapped onto a single pseudoatom (a blob) and the…

Soft Condensed Matter · Physics 2015-01-07 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

Compared to top-down coarse-grained (CG) models, bottom-up approaches are capable of offering higher structural fidelity. This fidelity results from the tight link to a higher-resolution reference, making the CG model chemically specific.…

Chemical Physics · Physics 2022-09-21 Kiran H. Kanekal , Joseph F. Rudzinski , Tristan Bereau

Modelling micro- and meso-scopic scale thermodynamic and transport properties of soft condensed matter hinges upon its representation. This is especially relevant for polar solvents such as water, since these require effective…

Soft Condensed Matter · Physics 2026-04-17 Michael A. Seaton , Benjamin T. Speake , Ilian T. Todorov

We present a coarse-grained model for linear polymers with a tunable number of effective atoms (blobs) per chain interacting by intra- and inter-molecular potentials obtained at zero density. We show how this model is able to accurately…

Soft Condensed Matter · Physics 2012-07-17 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

A persistent challenge in predictive molecular modeling of thermoset polymers is to capture the effects of chemical composition and degree of crosslinking (DC) on dynamical and mechanical properties with high computational efficiency. We…

Soft Condensed Matter · Physics 2021-10-15 Andrea Giuntoli , Nitin K. Hansoge , Anton van Beek , Zhaoxu Meng , Wei Chen , Sinan Keten
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