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Storage and retrieval of data in a computer memory plays a major role in system performance. Traditionally, computer memory organization is static - i.e., they do not change based on the application-specific characteristics in memory access…

Artificial Intelligence · Computer Science 2021-01-11 Prabuddha Chakraborty , Swarup Bhunia

Memory latency, bandwidth, capacity, and energy increasingly limit performance. In this paper, we reconsider proposed system architectures that consist of huge (many-terabyte to petabyte scale) memories shared among large numbers of CPUs.…

Hardware Architecture · Computer Science 2025-09-24 Samuel Dayo , Shuhan Liu , Peijing Li , Philip Levis , Subhasish Mitra , Thierry Tambe , David Tennenhouse , H. -S. Philip Wong

Scalable nonvolatile memory DIMMs will finally be commercially available with the release of the Intel Optane DC Persistent Memory Module (or just "Optane DC PMM"). This new nonvolatile DIMM supports byte-granularity accesses with access…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-13 Joseph Izraelevitz , Jian Yang , Lu Zhang , Juno Kim , Xiao Liu , Amirsaman Memaripour , Yun Joon Soh , Zixuan Wang , Yi Xu , Subramanya R. Dulloor , Jishen Zhao , Steven Swanson

Computational protein design is experiencing a transformation driven by AI/ML. However, the range of potential protein sequences and structures is astronomically vast, even for moderately sized proteins. Hence, achieving convergence between…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-09 Aymen Alsaadi , Jonathan Ash , Mikhail Titov , Matteo Turilli , Andre Merzky , Shantenu Jha , Sagar Khare

Deep Learning neural networks are pervasive, but traditional computer architectures are reaching the limits of being able to efficiently execute them for the large workloads of today. They are limited by the von Neumann bottleneck: the high…

Emerging Technologies · Computer Science 2022-06-22 Wilfried Haensch , Anand Raghunathan , Kaushik Roy , Bhaswar Chakrabarti , Charudatta M. Phatak , Cheng Wang , Supratik Guha

The byte-addressable Non-Volatile Memory (NVM) is a promising technology since it simultaneously provides DRAM-like performance, disk-like capacity, and persistency. The current NVM deployment is symmetric, where NVM devices are directly…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-31 Teng Ma , Mingxing Zhang , Kang Chen , Xuehai Qian , Yongwei Wu

Today's computing systems require moving data back-and-forth between computing resources (e.g., CPUs, GPUs, accelerators) and off-chip main memory so that computation can take place on the data. Unfortunately, this data movement is a major…

Hardware Architecture · Computer Science 2022-05-31 Geraldo F. Oliveira , Amirali Boroumand , Saugata Ghose , Juan Gómez-Luna , Onur Mutlu

This paper presents a tutorial and review of SRAM-based Compute-in-Memory (CIM) circuits, with a focus on both Digital CIM (DCIM) and Analog CIM (ACIM) implementations. We explore the fundamental concepts, architectures, and operational…

Hardware Architecture · Computer Science 2024-11-25 Kentaro Yoshioka , Shimpei Ando , Satomi Miyagi , Yung-Chin Chen , Wenlun Zhang

Modern computing systems are embracing hybrid memory comprising of DRAM and non-volatile memory (NVM) to combine the best properties of both memory technologies, achieving low latency, high reliability, and high density. A prominent…

Hardware Architecture · Computer Science 2020-05-12 Shihao Song , Anup Das , Nagarajan Kandasamy

The continuous shift of computational bottlenecks to the memory access and data transfer, especially for AI applications, poses the urgent needs of re-engineering the computer architecture fundamentals. Many edge computing applications,…

Systems and Control · Electrical Eng. & Systems 2025-01-31 Georgios Papandroulidakis , Shady Agwa , Ahmet Cirakoglu , Themis Prodromakis

Data movement between memory and processors is a major bottleneck in modern computing systems. The processing-in-memory (PIM) paradigm aims to alleviate this bottleneck by performing computation inside memory chips. Real PIM hardware (e.g.,…

Hardware Architecture · Computer Science 2023-10-04 Jinfan Chen , Juan Gómez-Luna , Izzat El Hajj , Yuxin Guo , Onur Mutlu

In this paper, we present GradPIM, a processing-in-memory architecture which accelerates parameter updates of deep neural networks training. As one of processing-in-memory techniques that could be realized in the near future, we propose an…

Machine Learning · Computer Science 2021-02-16 Heesu Kim , Hanmin Park , Taehyun Kim , Kwanheum Cho , Eojin Lee , Soojung Ryu , Hyuk-Jae Lee , Kiyoung Choi , Jinho Lee

The widespread adoption of cloud-based solutions introduces privacy and security concerns. Techniques such as homomorphic encryption (HE) mitigate this problem by allowing computation over encrypted data without the need for decryption.…

Cryptography and Security · Computer Science 2024-12-13 Mpoki Mwaisela , Joel Hari , Peterson Yuhala , Jämes Ménétrey , Pascal Felber , Valerio Schiavoni

Intel OptaneTM DC Persistent Memory resides on the memory bus and approaches DRAM in access latency. One avenue for its adoption is to employ it in place of persistent storage; another is to use it as a cheaper and denser extension of DRAM.…

Hardware Architecture · Computer Science 2022-05-30 Alexandra Fedorova , Keith Smith , Keith Bostic , Alexander Gorrod , Sue LoVerso , Michael Cahill

Raw signal genome analysis (RSGA) has emerged as a promising approach to enable real-time genome analysis by directly analyzing raw electrical signals. However, rapid advancements in sequencing technologies make it increasingly difficult…

Byte-addressable persistent memory (PM) brings hash tables the potential of low latency, cheap persistence and instant recovery. The recent advent of Intel Optane DC Persistent Memory Modules (DCPMM) further accelerates this trend. Many new…

Databases · Computer Science 2020-10-30 Baotong Lu , Xiangpeng Hao , Tianzheng Wang , Eric Lo

Compute-in-memory (CiM) is a promising approach to improving the computing speed and energy efficiency in dataintensive applications. Beyond existing CiM techniques of bitwise logic-in-memory operations and dot product operations, this…

Hardware Architecture · Computer Science 2023-01-03 Yiming Chen , Yushen Fu , Mingyen Lee , Sumitha George , Yongpan Liu , Vijaykrishnan Narayanan , Huazhong Yang , Xueqing Li

Despite the parallel in-memory search capabilities of content addressable memories (CAMs), their use in applications is constrained by their limited resolution that worsens as they are scaled to larger arrays or advanced nodes. In this work…

Emerging Technologies · Computer Science 2025-05-06 Siri Narla , Steven J. Koester , Rebecca A. Dawley , Ageeth A. Bol , Piyush Kumar , Azad Naeemi

Processing-in-memory (PIM) is a transformative architectural paradigm designed to overcome the Von Neumann bottleneck. Among PIM architectures, digital SRAM-PIM emerges as a promising solution, offering significant advantages by directly…

Hardware Architecture · Computer Science 2025-06-13 Cenlin Duan , Jianlei Yang , Yikun Wang , Yiou Wang , Yingjie Qi , Xiaolin He , Bonan Yan , Xueyan Wang , Xiaotao Jia , Weisheng Zhao

Persistent Memory (PMem), as already available, e.g., with Intel Optane DC Persistent Memory, represents a very promising, next-generation memory solution with a significant impact on database architectures. Several data structures for this…

Databases · Computer Science 2020-06-15 Philipp Götze , Arun Kumar Tharanatha , Kai-Uwe Sattler