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Multi-contrast MRI images provide complementary contrast information about the characteristics of anatomical structures and are commonly used in clinical practice. Recently, a multi-flip-angle (FA) and multi-echo GRE method (MULTIPLEX MRI)…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 Eric Z. Chen , Yongquan Ye , Xiao Chen , Jingyuan Lyu , Zhongqi Zhang , Yichen Hu , Terrence Chen , Jian Xu , Shanhui Sun

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Image registration is used in many medical image analysis applications, such as tracking the motion of tissue in cardiac images, where cardiac kinematics can be an indicator of tissue health. Registration is a challenging problem for deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Benjamin Graham

Limited-view computed tomography (CT) presents significant potential for reducing radiation exposure and expediting the scanning process. While deep learning (DL) methods have exhibited promising results in mitigating streaking artifacts…

Medical Physics · Physics 2025-02-18 Changyu Chen , Li Zhang , Yuxiang Xing , Zhiqiang Chen

Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…

Optics · Physics 2018-05-16 Kan Liu , Hui Qiao , Jiamin Wu , Haoqian Wang , Lu Fang , Qionghai Dai

Deep learning methods for accelerated MRI achieve state-of-the-art results but largely ignore additional speedups possible with noncartesian sampling trajectories. To address this gap, we created a generative diffusion model-based…

Artificial Intelligence · Computer Science 2024-10-02 Trevor J. Chan , Chamith S. Rajapakse

Deep-learning algorithms enable precise image recognition based on high-dimensional hierarchical image features. Here, we report the development and implementation of a deep-learning-based image segmentation algorithm in an autonomous…

Image and Video Processing · Electrical Eng. & Systems 2020-03-26 Satoru Masubuchi , Eisuke Watanabe , Yuta Seo , Shota Okazaki , Takao Sasagawa , Kenji Watanabe , Takashi Taniguchi , Tomoki Machida

The noise in diffusion-weighted images (DWIs) decreases the accuracy and precision of diffusion tensor magnetic resonance imaging (DTI) derived microstructural parameters and leads to prolonged acquisition time for achieving improved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Jonathan R. Polimeni , Berkin Bilgic , David H. Salat , Susie Y. Huang

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

The problem of unsupervised learning and segmentation of hyperspectral images is a significant challenge in remote sensing. The high dimensionality of hyperspectral data, presence of substantial noise, and overlap of classes all contribute…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 James M. Murphy , Mauro Maggioni

Traditional methods for biological shape inference, such as deep learning (DL) and active contour models, face important limitations in 3D. DL approaches require large annotated datasets, which are often impractical to obtain, while active…

Biological Physics · Physics 2025-08-04 Sacha Ichbiah , Anshuman Sinha , Fabrice Delbary , Hervé Turlier

Far-field characterization of small objects is severely constrained by the diffraction limit. Existing tools achieving sub-diffraction resolution often utilize point-by-point image reconstruction via scanning or labelling. Here, we present…

While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara

Computational image reconstruction algorithms generally produce a single image without any measure of uncertainty or confidence. Regularized Maximum Likelihood (RML) and feed-forward deep learning approaches for inverse problems typically…

Machine Learning · Computer Science 2020-12-18 He Sun , Katherine L. Bouman

Deep Neural Network (DNN)-based image reconstruction, despite many successes, often exhibits uneven fidelity between high and low spatial frequency bands. In this paper we propose the Learning Synthesis by DNN (LS-DNN) approach where two…

Computer Vision and Pattern Recognition · Computer Science 2018-11-21 Mo Deng , Shuai Li , George Barbastathis

A major challenge in computed tomography is reconstructing objects from incomplete data. An increasingly popular solution for these problems is to incorporate deep learning models into reconstruction algorithms. This study introduces a…

Numerical Analysis · Mathematics 2024-02-20 Knut Salomonsson , Eric Oldgren , Emanuel Ström , Ozan Öktem

Image decomposition aims to analyze an image into elementary components, which is essential for numerous downstream tasks and also by nature provides certain interpretability to the analysis. Deep learning can be powerful for such tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Sihan Wang , Shangqi Gao , Fuping Wu , Xiahai Zhuang

Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Adrian V. Dalca , Evan Yu , Polina Golland , Bruce Fischl , Mert R. Sabuncu , Juan Eugenio Iglesias

Understanding the complex myocardial architecture is critical for diagnosing and treating heart disease. However, existing methods often struggle to accurately capture this intricate structure from Diffusion Tensor Imaging (DTI) data,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Mohini Anand , Xavier Tricoche

We propose a model-based deep learning architecture for the reconstruction of highly accelerated diffusion magnetic resonance imaging (MRI) that enables high resolution imaging. The proposed reconstruction jointly recovers all the diffusion…

Image and Video Processing · Electrical Eng. & Systems 2020-01-24 Merry P. Mani , Hemant K. Aggarwal , Sanjay Ghosh , Mathews Jacob